If you made any changes in Pure these will be visible here soon.

Research Output 2000 2019

2019

Glycine microparticles loaded with functionalized nanoparticles for pulmonary delivery

Chakraborty, A., Royce, S. G., Plebanski, M. & Selomulya, C., 30 Oct 2019, In : International Journal of Pharmaceutics. 570, 9 p., 118654.

Research output: Contribution to journalArticleResearchpeer-review

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: Novel therapeutic target?

Garg, M., Royce, S. G., Tikellis, C., Shallue, C., Batu, D., Velkoska, E., Burrell, L. M., Patel, S. K., Beswick, L., Jackson, A., Britto, K., Lukies, M., Sluka, P., Wardan, H., Hirokawa, Y., Tan, C. W., Faux, M., Burgess, A. W., Hosking, P., Monagle, S. & 3 others, Thomas, M., Gibson, P. R. & Lubel, J., 13 Aug 2019, (Accepted/In press) In : Gut. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Relaxin and fibrosis: Emerging targets, challenges, and future directions

Kanai, A. J., Konieczko, E. M., Bennett, R. G., Samuel, C. S. & Royce, S. G., 1 May 2019, In : Molecular and Cellular Endocrinology. 487, p. 66-74 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Serelaxin enhances the therapeutic effects of human amnion epithelial cell-derived exosomes in experimental models of lung disease

Royce, S. G., Patel, K. P., Mao, W., Zhu, D., Lim, R. & Samuel, C. S., Jul 2019, In : British Journal of Pharmacology. 176, 13, p. 2195-2208 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in mouse model of acute myocardial infarction

McDonald, H., Peart, J., Kurniawan, N., Galloway, G., Royce, S., Samuel, C. S. & Chen, C., 13 May 2018, In : Physiological Reports. 6, 9, 14 p., e13699.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Insights into endotoxin-mediated lung inflammation and future treatment strategies

Chakraborty, A., Boer, J. C., Selomulya, C., Plebanski, M. & Royce, S. G., 2 Nov 2018, In : Expert Review of Respiratory Medicine. 12, 11, p. 941-955 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Serelaxin as a novel therapeutic opposing fibrosis and contraction in lung diseases

Lam, M., Royce, S. G., Samuel, C. S. & Bourke, J. E., Jul 2018, In : Pharmacology and Therapeutics. 187, p. 61-70 10 p.

Research output: Contribution to journalArticleOtherpeer-review

2017

Anti-fibrotic actions of relaxin

Samuel, C. S., Royce, S. G., Hewitson, T. D., Denton, K. M., Cooney, T. E. & Bennett, R. G., 1 May 2017, In : British Journal of Pharmacology. 174, 10, p. 962-976 15 p.

Research output: Contribution to journalArticleOtherpeer-review

2016

Airway remodeling and hyperreactivity in a model of bronchopulmonary dysplasia and their modulation by IL-1Ra

Royce, S. G., Nold, M. F., Bui, C. B-Q., Donovan, C., Lam, M., Lamanna, E., Rudloff, I., Bourke, J. E. & Nold-Petry, C. A., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 858-868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A prospective open clinical trial of a proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis

Philpott, H., Nandurkar, S., Royce, S. G., Thien, F. & Gibson, P. R., 1 May 2016, In : Alimentary Pharmacology and Therapeutics. 43, 9, p. 985-993 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1

Hossain, M. A., Kocan, M., Yao, S. T., Royce, S. G., Nair, V. B., Siwek, C., Patil, N. A., Harrison, I. P., Rosengren, K. J., Selemidis, S., Summers, R. J., Wade, J. D., Bathgate, R. A. D. & Samuel, C. S., 2016, In : Chemical Science. 7, 6, p. 3805-3819 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Combining an epithelial repair factor and anti-fibrotic with a corticosteroid offers optimal treatment for allergic airways disease

Patel, K. P., Giraud, A. S., Samuel, C. S. & Royce, S. G., 2016, In : British Journal of Pharmacology. 173, 12, p. 2016 - 2029 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

FitzPatrick, M., Royce, S. G., Langenbach, S., McQualter, J., Reading, P. C., Wijburg, O., Anderson, G. P., Stewart, A., Bourke, J. & Bozinovski, S., 2016, In : Scientific Reports. 6, p. 1 - 12 12 p., 22751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Promise and limitations of relaxin-based therapies in chronic fibrotic lung diseases

Royce, S. G., Bathgate, R. A. D. & Samuel, C. S., 1 Dec 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 11, p. 1434-1435 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Serelaxin elicits bronchodilation and enhances β-Adrenoceptor-mediated airway relaxation

Lam, M., Royce, S. G., Donovan, C., Jelinic, M., Parry, L. J., Samuel, C. S. & Bourke, J. E., 27 Oct 2016, In : Frontiers in Pharmacology. 7, 406, 18 p., 406.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Serelaxin improves the therapeutic efficacy of RXFP1-expressing human amnion epithelial cells in experimental allergic airway disease

Royce, S. G., Tominaga, A. M., Shen, M., Patel, K. P., Huuskes, B., Lim, R., Ricardo, S. D. & Samuel, C. S., 2016, In : Clinical Science. 130, 23, p. 2151-2165 15 p.

Research output: Contribution to journalArticleResearchpeer-review

The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2–Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation

Schuliga, M., Royce, S. G., Langenbach, S., Berhan, A., Harris, T., Keenan, C. R. & Stewart, A. G., 2016, In : American Journal of Respiratory Cell and Molecular Biology. 54, 2, p. 200-209 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Ultrathin unsedated transnasal gastroscopy in monitoring eosinophilic esophagitis

Philpott, H., Nandurkar, S., Royce, S. G. & Gibson, P. R., 1 Mar 2016, In : Journal of Gastroenterology and Hepatology. 31, 3, p. 590-594 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Alteration of airway reactivity and reduction of ryanodine receptor expression by cigarette smoke in mice

Donovan, C., Seow, H. J., Royce, S. G., Bourke, J. E. & Vlahos, R., 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 4, p. 471 - 478 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Dietary sulforaphane in cancer chemoprevention: the role of epigenetic regulation and HDAC inhibition

Tortorella, S., Royce, S. G., Licciardi, P. V. & Karagiannis, T. C., 2015, In : Antioxidants and Redox Signaling. 22, 16, p. 1382 - 1424 43 p.

Research output: Contribution to journalArticleResearchpeer-review

Electrophysiological, electroanatomical, and structural remodeling of the atria as consequences of sustained obesity

Mahajan, R., Lau, D. H., Brooks, A. G., Shipp, N. J., Manavis, J., Wood, J. P. M., Finnie, J. W., Samuel, C. S., Royce, S. G., Twomey, D. J., Thanigaimani, S., Kalman, J. M. & Sanders, P., 2015, In : Journal of the American College of Cardiology. 66, 1, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Eosinophilic esophagitis: A clinicopathological review

Philpott, H., Nandurkar, S., Thien, F., Gibson, P. R. & Royce, S. G., 2015, In : Pharmacology and Therapeutics. 146, p. 12 - 22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

IgG and EoE: Too soon for a paradigm shift away from IgE

Philpott, H., Royce, S. G., Nandurkar, S., Thien, F. C. K. & Gibson, P. R., 2015, In : Gastroenterology. 148, 2, p. 453 - 454 2 p.

Research output: Contribution to journalLetterOther

Lipopolysaccharide does not alter small airway reactivity in mouse lung slices

Donovan, C., Royce, S. G., Vlahos, R. & Bourke, J. E., 2015, In : PLoS ONE. 10, 3, 16 p., e0122069.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Mesenchymal stem cells and serelaxin synergistically abrogate established airway fibrosis in an experimental model of chronic allergic airways disease

Royce, S. G., Shen, M., Patel, K. P., Huuskes, B., Ricardo, S. D. & Samuel, C. S., 2015, In : Stem Cell Research. 15, 3, p. 495 - 505 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease

Donovan, C., Bailey, S. R., Tran, J., Haitsma, G., Ibrahim, Z. A., Foster, S. R., Tang, M. L. K., Royce, S. G. & Bourke, J. E., 2015, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 309, 10, p. 1219 - 1228 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Seasonal recurrence of food bolus obstruction in eosinophilic esophagitis

Philpott, H., Nandurkar, S., Thien, F. C. K., Bloom, S. D., Lin, E., Goldberg, R., Boyapati, R., Finch, A., Royce, S. G. & Gibson, P. R., 2015, In : Internal Medicine Journal. 45, 9, p. 939 - 943 5 p.

Research output: Contribution to journalArticleResearchpeer-review

What gastroenterologists should know about testing patients with eosinophilic esophagitis for food allergies

Philpott, H., Royce, S. G., Thien, F. C. K., Nandurkar, S. & Gibson, P. R., 2015, In : Clinical Gastroenterology and Hepatology. 13, 5, p. 1029 - 1030 2 p.

Research output: Contribution to journalLetterOtherpeer-review

2014

Cell cycle effects of L-sulforaphane, a major antioxidant from cruciferous vegetables: The role of the anaphase promoting complex

Li, Z. S., Royce, S. G., Ververis, K. & Karagiannis, T. C., 2014, In : Hellenic Journal of Nuclear Medicine. 17, p. 11-16 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma

Royce, S. G., Patel, K. P. & Samuel, C. S., 2014, In : Laboratory Investigation. 94, 12, p. 1326 - 1339 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Intranasally administered serelaxin abrogates airway remodelling and attenuates airway hyperresponsiveness in allergic airways disease

Royce, S. G., Lim, C., Patel, K. P., Wang, B., Samuel, C. S. & Tang, M. L. K., 2014, In : Clinical and Experimental Allergy. 44, 11, p. 1399 - 1408 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mechanistic insights into the contribution of epithelial damage to airway remodeling. Novel therapeutic targets for asthma

Royce, S. G., Li, X., Tortorella, S., Goodings, L. M., Chow, B. SM., Giraud, A. S., Tang, M. L. K. & Samuel, C. S., 2014, In : American Journal of Respiratory Cell and Molecular Biology. 50, 1, p. 180 - 192 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular mechanisms in the development and progression of asthma: The role of epigenetic regulation and the airway epithelium

Tortorella, S., Royce, S. G. & Karagiannis, T. C., 1 Feb 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Maulik, N. & Karagiannis, T. (eds.). New York NY USA: Springer, p. 219-245 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis

Royce, S. G., Moodley, Y. & Samuel, C. S., 2014, In : Pharmacology and Therapeutics. 141, 3, p. 250 - 260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Risk factors for eosinophilic esophagitis

Philpott, H., Nandurkar, S., Royce, S. G., Thien, F. & Gibson, P. R., 2014, In : Clinical and Experimental Allergy. 44, 8, p. 1012 - 1019 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of caveolin-1 in asthma and chronic inflammatory respiratory diseases

Royce, S. G. & Le Saux, C. J., 2014, In : Expert Review of Respiratory Medicine. 8, 3, p. 339 - 347 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Serelaxin is a more efficacious antifibrotic than enalapril in an experimental model of heart disease

Samuel, C. S., Bodaragama, H., Chew, J., Widdop, R. E., Royce, S. G. & Hewitson, T. D., 2014, In : Hypertension. 64, 2, p. 315 - 322 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of gas exchange on multiple-breath nitrogen washout measures of ventilation inhomogeneity in the mouse

Dharmakumara, M., Prisk, G. K., Royce, S. G., Tawhai, M. & Thompson, B. R., 2014, In : Journal of Applied Physiology. 117, 9, p. 1049 - 1054 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/- mice

Gabehart, K. E., Royce, S. G., Maselli, D. J., Miyasato, S. K., Davis, E. C., Tang, M. L. K. & Jourdan Le Saux, C., 21 Oct 2013, In : Respiratory Research. 14, 1, p. 1-11 11 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Differential effects of allergen challenge on large and small airway reactivity in mice

Donovan, C., Royce, S. G., Esposito, J., Tran, J., Ibrahim, Z. A., Tang, M. L. K., Bailey, S. & Bourke, J. E., 6 Sep 2013, In : PLoS ONE. 8, 9, p. 1-8 8 p., e74101.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation

Abed, H. S., Samuel, C. S., Lau, D. H., Kelly, D. J., Royce, S. G., Alasady, M., Mahajan, R., Kuklik, P., Zhang, Y. M., Brooks, A. G., Nelson, A. J., Worthley, S. G., Abhayaratna, W., Kalman, J., Wittert, G. G. & Sanders, P., 2013, In : Heart Rhythm. 10, 1, p. 90 - 100 11 p.

Research output: Contribution to journalArticleResearchpeer-review