Projects per year
Personal profile
Biography
Dr. Shobi Sivathamboo is internationally recognised for her work on sudden unexpected death in epilepsy (SUDEP). She leads the SUDEP research group at Monash University, which has a focus on uncovering the incidence and biomarkers for SUDEP risk, as well as developing novel technologies for out-of-hospital seizure detection, timely alerts, and early detection of high-risk individuals.
She completed her PhD at the University of Melbourne in 2019 on cardiorespiratory function in epilepsy, which discovered that ~10% of patients with chronic drug-resistant epilepsy had serious cardiac abnormalities identified through long-term subcutaneous monitoring, that went undetected from routine epilepsy and cardiac investigations.
She has obtained funding totalling >$2.5M from competitive and industry funding bodies, and currently holds an NHMRC Emerging Leadership Grant. She has published in several leading peer-reviewed journals and been an invited speaker at various national and international forums, including the International Epilepsy Congress, Epilepsy Society of Australia, and the Canadian League Against Epilepsy. She is a member of the International League Against Epilepsy (ILAE) SUDEP Task Force. She is a principal investigator for the largest global efforts to study SUDEP risk factors and biomarkers across 86 epilepsy centres.
External positions
Research Fellow, Alfred Hospital
8 Apr 2019 → …
Research area keywords
- Sudden unexpected death in epilepsy (SUDEP)
- Cardiac disease
- Epilepsy
- Seizure detection
- Wearables
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Identifying Clinical Biomarkers and Developing Multimodal Risk Prediction Tools for SUDEP Prevention
Sivathamboo, S. (Primary Chief Investigator (PCI)), Devinsky, O. (Chief Investigator (CI)), Laze, J. (Chief Investigator (CI)), Kwan, P. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Kuhlmann, L. (Chief Investigator (CI)), Chen, Z. (Chief Investigator (CI)), Nhu, D. (Chief Investigator (CI)), Liu, J. (Chief Investigator (CI)), Harikar, M. (Chief Investigator (CI)), Bateman, L. (Associate Investigator (AI)), Nashef, L. (Associate Investigator (AI)) & Stavropoulos, L. (Associate Investigator (AI))
19/05/26 → 18/05/28
Project: Research
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Preventing sudden unexpected death in epilepsy: Discovery of predictive biomarkers and risk factors for precision-based care
Sivathamboo, S. (Primary Chief Investigator (PCI))
1/01/24 → 31/12/28
Project: Research
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Cardiorespiratory function as a non-invasive biomarker for detecting seizures with artificial intelligence: Utilising data from long-term patient recordings from an epilepsy monitoring unit
O'Brien, T. (Primary Chief Investigator (PCI)), Kwan, P. (Chief Investigator (CI)), Sivathamboo, S. (Chief Investigator (CI)), Perucca, P. (Chief Investigator (CI)), Ge, Z. (Chief Investigator (CI)), Le, T. (Chief Investigator (CI)), Phung, D. (Chief Investigator (CI)), Bonnington, P. (Chief Investigator (CI)) & Piccenna, L. (Project Manager)
8/04/19 → 8/04/20
Project: Research
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A retrospective audit of the real-world safety and effectiveness profile of eptinezumab for treatment-resistant chronic migraine in Australia
Gunasekera, L. (Leading Author), Cheng, S., Foster, E., Sivathamboo, S., O'Brien, T., Butzkueven, H., Kulkarni, J. & Hutton, E. (Leading Author), Jan 2026, In: Headache. 66, 1, p. 108-117 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Privacy-Centric Seizure Detection Using Surface Normals, Pose and Segmentation Masks
Ponnambalam, K. G., Ilyas, T., Sivathamboo, S., Ge, Z., Kwan, P., Kuhlmann, L. & Mehta, D., 2026, 38th Australasian Joint Conference on Artificial Intelligence, AI 2025 Canberra, ACT, Australia, December 1–5, 2025 Proceedings, Part II. Liu, M., Yu, X., Xu, C. & Song, Y. (eds.). Singapore Singapore: Springer, p. 322-334 13 p. (Lecture Notes in Computer Science; vol. 16371).Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review
1 Link opens in a new tab Citation (Scopus) -
Cardiac structural and molecular alterations in rodent models of temporal lobe epilepsy
Liu, Z. (Leading Author), Sivathamboo, S., Thergarajan, P., Gomes, F. M., Ali, I., Powell, K. L., Perucca, P., Jones, N. C., O'Brien, T. J. & Casillas-Espinosa, P. (Leading Author), Jun 2025, In: Epilepsia Open. 10, 3, p. 809-821 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Channel-annotated deep learning for enhanced interpretability in EEG-based seizure detection
Wong, S., Simmons, A., Rivera-Villicana, J., Barnett, S., Sivathamboo, S., Perucca, P., Ge, Z., Kwan, P., Kuhlmann, L. & O'Brien, T. J., May 2025, In: Biomedical Signal Processing and Control. 103, 17 p., 107484.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Link opens in a new tab Citations (Scopus) -
Stop and sniff the roses: Insights into the voluntary control of respiration
Simpson, H. D., Sivathamboo, S. & Bateman, L. M., 15 Feb 2025, In: The Journal of Physiology. 603, 4, p. 779-780 2 p.Research output: Contribution to journal › Article › Other › peer-review
Prizes
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Bridging Postdoctoral Fellowship 2020
Sivathamboo, S. (Recipient), 11 Dec 2019
Prize: Competitive Fellowships
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Developing Predictive Biomarkers of Epilepsy Seizures
Sivathamboo, S. (Recipient), O'Brien, T. (Recipient), Kwan, P. (Recipient), Vasa, R. (Recipient), Mouzakis, K. (Recipient), Jones, N. (Recipient), Goldin, J. (Recipient), Pastorello, N. (Recipient) & Mitrevska, M. (Recipient), 20 Dec 2016
Prize: Prize (including medals and awards)