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Personal profile

Research interests

Neuroscience, neurodegneration,neuropharmacology,  Alzheimer disease, Epilepsy, traumatic brain injury, stroke, biochemistry, cellular biology, molecular biology and morphology


Postdoctoral Research Fellow, the Afred Center, Monash University, Melbourne, Australia, 2018-present

Postdoctoral Research Fellow, Royal Melbourne Hospital, University of Melbourne. Melbourne, Australia, 2011.5-2017.12

Postdoctoral Research Fellow, Menizes Research Institute, University of Tasmania, Hobart, Australia, 2008.5-2011.4

Postdoctoral Research Fellow, The Burnham institute for medical research (Sandford Burnham Prebys Medical Discovery Institute), La Jolla, California, USA, 2005.10-2008.4

Postdoctoral Research Fellow, Physiopathologie du Système Nerveus, INSERM, Strasbourg, France, 2004.9-2005.8

Assistant Professor, Xinqiao Hosptial, The Thrid Medical Univiersity, Chongqing, China, 2003.6-2004.6

Postdoctoral Research Fellow, Tongji Medical College, Huazhong Univeristy of Science and Technology, Wuhan, China, 2000.10-2003.6





Research area keywords

  • Alzheimer's Disease
  • epilepsy, seizure, EEG, semiology
  • Traumatic brain injury
  • Stroke
  • Neuroscience
  • Biochemistry and Cell Biology
  • Molecular Cell Biology
  • Neurological Disorders

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Research Output 2002 2019

3 Citations (Scopus)

Targeting neurodegeneration to prevent post-traumatic epilepsy

Ali, I., de Castro e Silva, J., Liu, S., Shultz, S. R., Kwan, P., Jones, N. C. & O'Brien, T. J., Mar 2019, In : Neurobiology of Disease. 123, p. 100-109 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury

Tan, X. L., Sun, M., Brady, R. D., Liu, S., Llanos, R. M., Cheung, S., Wright, D. K., Casillas-Espinosa, P. M., Sashindranath, M., O'Brien, T. J., McDonald, S. J., Turner, B. J. & Shultz, S., 1 Jan 2019, In : Journal of Neurotrauma. 36, 1, p. 87-99 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice

Liu, S., Shen, Y., Shultz, S. R., Nguyen, A., Hovens, C., Adlard, P. A., Bush, A. I., Chan, J., Kwan, P., O'Brien, T. J. & Jones, N. C., 1 Sep 2017, In : Epilepsia. 58, 9, p. e136-e141 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Traumatic brain injury results in cellular, structural and functional changes resembling motor neuron disease

Wright, D. K., Liu, S., Van Der Poel, C., McDonald, S. J., Brady, R. D., Taylor, L., Yang, L., Gardner, A. J., Ordidge, R., O'Brien, T. J., Johnston, L. A. & Shultz, S. R., 2017, In : Cerebral Cortex. 27, 9, p. 4503-4515 13 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes

Tan, X. L., Wright, D. K., Liu, S., Hovens, C., O'Brien, T. J. & Shultz, S. R., 1 Sep 2016, In : Neuropharmacology. 108, p. 382-393 12 p.

Research output: Contribution to journalArticleResearchpeer-review


The mechanisms of hyperphosphorlated tau in Alzheimer disease, State Natural Science Award, The second prize in China

Shijie Liu (Recipient), Jian-Zhi Wang (Recipient), Hong-Lian Li (Recipient), Dan-Ling Wang (Recipient) & Zhou-Hua Zhang (Recipient), 2010

Prize: Prize (including medals and awards)