Shay McGuinness

Dr

20092022
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Research Output 2009 2019

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2019

Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Chan, M. T. V., Wallace, S., Forbes, A. & for the ATACAS investigators and the ANZCA Clinical Trials Network, Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 633-640

Research output: Contribution to journalArticleResearchpeer-review

Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial

Myles, P. S., Smith, J. A., Kasza, J., Silbert, B., Jayarajah, M., Painter, T., Cooper, D. J., Marasco, S., McNeil, J., Bussières, J. S., McGuinness, S., Byrne, K., Chan, M. T. V., Landoni, G., Wallace, S., Forbes, A. & ATACAS investigators and the ANZCA Clinical Trials Network, 1 Feb 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 2, p. 644-652 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): Study protocol

Young, P. J., Bagshaw, S. M., Forbes, A., Nichol, A., Wright, S. E., Bellomo, R., Bailey, M. J., Beasley, R. W., Eastwood, G. M., Festa, M., Gattas, D., van Haren, F., Litton, E., Mouncey, P., Navarra, L., Pilcher, D., Mackle, D., McArthur, C. J., McGuinness, S. P., Saxena, M. K. & 4 othersWebb, S., Rowan, K. M., Australian and New Zealand Intensive Care Society Clinical Trials Group & PEPTIC investigators, 1 Sep 2018, In : Critical Care and Resuscitation. 20, 3, p. 182-189 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Position paper for the organization of ECMO programs for cardiac failure in adults

Abrams, D., Garan, A. R., Abdelbary, A., Bacchetta, M., Bartlett, R. H., Beck, J., Belohlavek, J., Chen, Y. S., Fan, E., Ferguson, N. D., Fowles, J. A., Fraser, J., Gong, M., Hassan, I. F., Hodgson, C., Hou, X., Hryniewicz, K., Ichiba, S., Jakobleff, W. A., Lorusso, R. & 19 othersMacLaren, G., McGuinness, S., Mueller, T., Park, P. K., Peek, G., Pellegrino, V., Price, S., Rosenzweig, E. B., Sakamoto, T., Salazar, L., Schmidt, M., Slutsky, A. S., Spaulding, C., Takayama, H., Takeda, K., Vuylsteke, A., Combes, A., Brodie, D. & for The International ECMO Network (ECMONet) and The Extracorporeal Life Support Organization (ELSO), Jun 2018, In : Intensive Care Medicine. 44, 6, p. 717-729 13 p.

Research output: Contribution to journalArticleOtherpeer-review

Restrictive versus liberal fluid therapy for major abdominal surgery

Myles, P. S., Bellomo, R., Corcoran, T., Forbes, A., Peyton, P., Story, D., Christophi, C., Leslie, K., McGuinness, S., Parke, R., Serpell, J., Chan, M. T. V., Painter, T., McCluskey, S., Minto, G. & Wallace, S., 14 Jun 2018, In : New England Journal of Medicine. 378, 24, p. 2263-2274 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Six-Month Outcomes After High-Risk Coronary Artery Bypass Graft Surgery and Preoperative Intra-aortic Balloon Counterpulsation Use: An Inception Cohort Study

Litton, E., Bass, F., Delaney, A., Hillis, G., Marasco, S., McGuinness, S., Myles, P. S., Reid, C. M., Smith, J. A. & the PINBALL study investigators and the ANZICS CTG, 1 Oct 2018, In : Journal of Cardiothoracic and Vascular Anesthesia. 32, 5, p. 2067-2073 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Supplemental parenteral nutrition versus usual care in critically ill adults: A pilot randomized controlled study

Ridley, E. J., Davies, A. R., Parke, R., Bailey, M., McArthur, C., Gillanders, L., Cooper, D. J., McGuinness, S. & and for the Supplemental Parenteral Nutrition Clinical Investigators, 23 Jan 2018, In : Critical Care. 22, 1, 11 p., 12.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017

Protocol and statistical analysis plan for the randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial

Young, P. J., Bailey, M. J., Beasley, R. W., Freebairn, R. C., Hammond, N. E., Van Haren, F. M. P., Harward, M. L., Henderson, S. J., Mackle, D. M., McArthur, C. J., McGuinness, S. P., Myburgh, J. A., Saxena, M. K., Turner, A., Webb, S. A. R., Bellomo, R. & The ANZICS Clinical Trials Group, 2017, In : Critical Care and Resuscitation. 19, 1, p. 81-87 7 p.

Research output: Contribution to journalArticleOtherpeer-review

Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): Rationale and design for a multicentre randomised trial

Myles, P., Bellomo, R., Corcoran, T., Forbes, A., Wallace, S., Peyton, P., Christophi, C., Story, D., Leslie, K., Serpell, J., McGuinness, S., Parke, R., Australian and New Zealand College of Anaesthetists Clinical Trials Network & Australian and New Zealand Intensive Care Society Clinical Trials Group, 1 Mar 2017, In : BMJ Open. 7, 3, 9 p., e015358.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Tranexamic acid in patients undergoing coronary-artery surgery

Myles, P. S., Smith, J. A., Forbes, A., Silbert, B. & the ATACAS Investigators of the ANZCA Clinical Trials Network, 12 Jan 2017, In : New England Journal of Medicine. 376, 2, p. 136-148 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

A multicenter, randomized, controlled phase IIb trial of avoidance of hyperoxemia during cardiopulmonary bypass

McGuinness, S. P., Parke, R. L., Drummond, K., Willcox, T., Bailey, M. & SO-COOL investigators, 1 Sep 2016, In : Anesthesiology. 125, 3, p. 465-473 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of dexmedetomidine added to standard care on ventilator-free time in patients with agitated delirium: A randomized clinical trial

Reade, M. C., Eastwood, G. M., Bellomo, R., Bailey, M., Bersten, A., Cheung, B., Davies, A., Delaney, A., Ghosh, A., Van Haren, F., Harley, N., Knight, D., McGuiness, S., Mulder, J., O'Donoghue, S., Simpson, N., Young, P., DahLIA Investigators & Australian and New Zealand Intensive Care Society Clinical Trials Group, 12 Apr 2016, In : JAMA. 315, 14, p. 1460-1468 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Targeted therapeutic mild hypercapnia after cardiac arrest: A phase II multi-centre randomised controlled trial (the CCC trial)

Eastwood, G. M., Schneider, A. G., Suzuki, S., Peck, L., Young, H., Tanaka, A., Mårtensson, J., Warrillow, S., McGuinness, S., Parke, R., Gilder, E., Mccarthy, L., Galt, P., Taori, G., Eliott, S., Lamac, T., Bailey, M., Harley, N., Barge, D., Hodgson, C. L. & 8 othersMorganti-Kossmann, M. C., Pebay, A., Conquest, A., Archer, J. S., Bernard, S., Stub, D., Hart, G. K. & Bellomo, R., 1 Jul 2016, In : Resuscitation. 104, p. 83-90 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Acetaminophen for fever in critically iII patients with suspected infection

Young, P. J., Saxena, M. K., Bellomo, R., Freebairn, R. C., Hammond, N. E., Van Haren, F. M. P., Holliday, M., Henderson, S. J., Mackle, D., McArthur, C., McGuinness, S. P., Myburgh, J. A., Weatherall, M. W., Webb, S. A. R. & Beasley, R. W., 2015, In : New England Journal of Medicine. 373, 23, p. 2215 - 2224 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A Randomised feasibility study to assess a novel strategy to rationalise fluid in patients after cardiac surgery

Parke, R. L., McGuinness, S. P., Gilder, E., McCarthy, L. & Cowdrey, K. A. L., 1 Jul 2015, In : British Journal of Anaesthesia. 115, 1, p. 45-52 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: The SPLIT randomized clinical trial

Young, P. J., Bailey, M. J., Beasley, R. W., Henderson, S. J., Mackle, D., McArthur, C., McGuinness, S. P., Mehrtens, J., Myburgh, J. A., Psirides, A., Reddy, S. K. & Bellomo, R., 2015, In : JAMA. 314, 16, p. 1701 - 1710 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of very-high-flow nasal therapy on airway pressure and end-expiratory lung impedance in healthy volunteers

Parke, R. L., Bloch, A. & McGuinness, S. P., 2015, In : Respiratory care. 60, 10, p. 1397 - 1403 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Overview of the study protocols and statistical analysis plan for the saline versus Plasma-Lyte 148 for intravenous fluid therapy (SPLIT) research program

Reddy, S. K., Young, P. J., Beasley, R. W., Mackle, D., McGuinness, S. P., McArthur, C., Henderson, S. J., Weinberg, L., French, C. J., Orford, N., Bailey, M. J. & Bellomo, R., 2015, In : Critical Care and Resuscitation. 17, 1, p. 29 - 36 8 p.

Research output: Contribution to journalArticleOther

Sodium bicarbonate and renal function after cardiac surgery: a prospectively planned individual patient meta-analysis

Bailey, M. J., McGuinness, S. P., Haase, M., Haase-Fielitz, A., Parke, R. L., Hodgson, C. L., Forbes, A. B., Bagshaw, S. M. & Bellomo, R., 2015, In : Anesthesiology. 122, 2, p. 294 - 306 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Supplemental parenteral nutrition in critically ill patients: a study protocol for a phase II randomised controlled trial

Ridley, E. J., Davies, A. R., Parke, R. L., Bailey, M. J., McArthur, C., Gillanders, L., Cooper, D. J. & McGuinness, S. P., 2015, In : Trials. 16, 1, p. 1-9 9 p., 587.

Research output: Contribution to journalArticleOther

Open Access
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2014

A multicentre feasibility study evaluating stress ulcer prophylaxis using hospital-based registry data

Litton, E., Eastwood, G. M., Bellomo, R., Beasley, R. W., Bailey, M. J., Forbes, A. B., Gattas, D. J., Pilcher, D. V., Webb, S. A. R., McGuinness, S. P., Saxena, M. K., McArthur, C. & Young, P. J., 2014, In : Critical Care and Resuscitation. 16, 3, p. 158 - 163 6 p.

Research output: Contribution to journalArticleResearchpeer-review

A protocol for the 0.9% saline versus Plasma-Lyte 148 for intensive care fluid therapy (SPLIT) study

Reddy, S. K., Bailey, M. J., Beasley, R. W., Bellomo, R., Henderson, S. J., Mackle, D., McArthur, C., Mehrtens, J., Myburgh, J. A., McGuinness, S. P., Psirides, A. & Young, P. J., 2014, In : Critical Care and Resuscitation. 16, 4, p. 274 - 279 6 p.

Research output: Contribution to journalArticleOther

Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial

Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M. P., Lee, J., Lo, S., McArthur, C., McGuinness, S., Myburgh, J., Norton, R. & Scheinkestel, C., 14 Mar 2014, In : Critical Care. 18, 2, 11 p., R45.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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HyperOxic Therapy OR NormOxic Therapy after out-of-hospital cardiac arrest (HOT OR NOT): a randomised controlled feasibility trial

Young, P. J., Bailey, M. J., Bellomo, R., Bernard, S. A., Dicker, B., Freebairn, R. C., Henderson, S. J., Mackle, D., McArthur, C., McGuinness, S. P., Smith, T. N., Weatherall, M. W. & Beasley, R. W., 2014, In : Resuscitation. 85, 12, p. 1686 - 1691 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Intravenous fluid use after cardiac surgery: a multicentre, prospective, observational study

Parke, R. L., McGuinness, S. P., Gilder, E. & McCarthy, L., 2014, In : Critical Care and Resuscitation. 16, 3, p. 164 - 169 6 p.

Research output: Contribution to journalArticleResearchpeer-review

KHA-CARI guideline: KHA-CARI adaptation of the KDIGO Clinical Practice Guideline for Acute Kidney Injury

Langham, R. G., Bellomo, R., D'Intini, V., Endre, Z. H., Hickey, B., McGuinness, S. P., Phoon, R. K. S., Salamon, K., Woods, J. & Gallagher, M. P., 2014, In : Nephrology. 19, 5, p. 261 - 265 5 p.

Research output: Contribution to journalArticleOther

Long-Term Survival and Dialysis Dependency Following Acute Kidney Injury in Intensive Care: Extended Follow-up of a Randomized Controlled Trial

Gallagher, M., Cass, A., Bellomo, R., Finfer, S., Gattas, D. J., Lee, J., Lo, S., McGuinness, S., Myburgh, J., Parke, R. & Rajbhandari, D., 1 Feb 2014, In : PLoS Medicine. 11, 2, e1001601.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The relationship between hypophosphataemia and outcomes during low-intensity and high-intensity continuous renal replacement therapy

Bellomo, R., Cass, A., Cole, L., Finfer, S. R., Gallagher, M. P., Kim, I., Lee, J., Lo, S., McArthur, C., McGuinness, S. P., Norton, R., Myburgh, J. A. & Scheinkestel, C. D., 2014, In : Critical Care and Resuscitation. 16, 1, p. 34 - 41 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis

Bellomo, R., Lipcsey, M., Calzavacca, P., Haase, M., Haase-Fielitz, A., Licari, E., Tee, A., Cole, L., Cass, A., Finfer, S. R., Gallagher, M. P., Lee, J., Lo, S., McArthur, C., McGuinness, S. P., Myburgh, J. A. & Scheinkestel, C. D., 2013, In : Intensive Care Medicine. 39, p. 429-436 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Sodium bicarbonate infusion to reduce cardiac surgery-associated acute kidney injury: a phase II multicenter double-blind randomized controlled trial

McGuinness, S., Parke, R. L., Bellomo, R., Van Haren, F. M. P. & Bailey, M. J., 2013, In : Critical Care Medicine. 41, 7, p. 1599 - 1607 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Statistical analysis plan for the HEAT trial: a multicentre randomised placebo-controlled trial of intravenous paracetamol in intensive care unit patients with fever and infection

Young, P. J., Weatherall, M. W., Saxena, M. K., Bellomo, R., Freebairn, R. C., Hammond, N. E., Van Haren, F. M. P., Henderson, S. J., McArthur, C., McGuinness, S., Mackle, D., Myburgh, J. A., Webb, S. A. R. & Beasley, R. W., 2013, In : Critical Care and Resuscitation. 15, 4, p. 279 - 286 8 p.

Research output: Contribution to journalArticleOther

2012

An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial

The RENAL Replacement Therapy Study Investigators, 1 Jan 2012, In : Critical Care Medicine. 40, 6, p. 1753-1760 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Hydroxyethyl starch or saline for fluid resuscitation in intensive care

Myburgh, J. A., Finfer, S. R., Bellomo, R., Billot, L., Cass, A., Gattas, D. J., Glass, P., Lipman, J., Liu, B., McArthur, C., McGuinness, S. P., Rajbhandari, D., Taylor, C. B. & Webb, S. A. R., 2012, In : New England Journal of Medicine. 367, 20, p. 1901 - 1911 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The HEAT trial: A protocol for a multicentre randomised placebo-controlled trial of IV paracetamol in ICU patients with fever and infection

Young, P. J., Saxena, M. K., Bellomo, R., Freebairn, R. C., Hammond, N. E., van Haren, F. M. P., Henderson, S. J., McArthur, C. J., McGuinness, S. P., Mackle, D., Myburgh, J. A., Weatherall, M., Webb, S. A. R. & Beasley, R. W., 1 Dec 2012, In : Critical Care and Resuscitation. 14, 4, p. 290-296 7 p.

Research output: Contribution to journalArticleOtherpeer-review

2011

Experience with high frequency oscillation ventilation during the 2009 H1N1 influenza pandemic in Australia and New Zealand

Boots, R., Lipman, J., Lassig-Smith, M., Stephens, D., Thomas, J., Shehabi, Y., Bass, F., Anthony, A., Long, D., Seppelt, I. M., Weisbrodt, L., Erickson, S., Beca, J., Sherring, C., McGuinness, S. P., Parke, R., Stachowski, E., Boyd, R. & Howe, B., 2011, In : Anaesthesia and intensive care. 39, 5, p. 837 - 846 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The crystalloid versus hydroxyethyl starch trial: Protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality

Myburgh, J., Bellomo, R., Cass, A., French, J., Finfer, S., Gattas, D., Glass, P., Lee, J., Lipman, J., Liu, B., McArthur, C., McGuinness, S., Rajbhandari, D., Taylor, C. & Webb, S., 1 May 2011, In : Intensive Care Medicine. 37, 5, p. 816-823 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome

Davies, A., Jones, D., Bailey, M., Beca, J., Bellomo, R., Blackwell, N., Forrest, P., Gattas, D., Granger, E., Herkes, R., Jackson, A., McGuinness, S., Nair, P., Pellegrino, V., Pettila, V. Y. O., Plunkett, B., Pye, R., Torzillo, P., Webb, S., Wilson, M. & 1 othersZiegenfuss, M., 2009, In : JAMA. 302, 17, p. 1888 - 1895 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Intensity of continuous renal-replacement therapy in critically ill patients

Bellomo, R., Cass, A., Cole, L., Finfer, S. R., Gallagher, M. P., Lo, S., McArthur, C., McGuinness, S. P., Myburgh, J. A., Norton, R., Scheinkestel, C. D. & Su, S. Y-S., 2009, In : New England Journal of Medicine. 361, 17, p. 1627 - 1638 12 p.

Research output: Contribution to journalArticleResearchpeer-review