Dr Senthil Arumugam obtained his PhD training in the lab of Prof Petra Schwille at the Max Planck Institute for Cell Biology and Genetics in Dresden, Germany, focusing on self-organisation of proteins involved in bacterial cell division.His post-doctoral work in the labs of Prof Patricia Bassereau and Prof Ludger Johannes at the Curie Institute, Paris, France, focused on protein-membrane interactions and cellular trafficking.Dr Arumugam joined Single Molecule Science at the University of New South Wales as an independent group leader in September 2016 and established the Lattice Light-Sheet Imaging infrastructure with his research focused on endosomal trafficking.Since October 2019, he is an EMBL Australia Group Leader at the Monash Biomedicine Discovery Institute, with the lab focussing on fundamental questions in intracellular trafficking and their role in cell fate specification and pattern formation in development using LLSM and MOSAIC. 

We aim to understand how complex properties arise out of molecules and their interactions, with a primary focus on endosomal trafficking at the level of single cells and in the context of intercellular communications in development. To enable this, we use advanced fluorescence imaging and spectroscopy methods that include Lattice Light Sheets, Adaptive Optics based light sheets, single molecule imaging and other related techniques, complemented by computational data analysis and mathematical modelling. Our broad areas of interests are:

• Cell biology and developmental biology
• Advanced fluorescence imaging, optogenetics, image and data analysis
• Self-organisation, and pattern formation