Senthil Arumugam

Dr

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20082024

Research activity per year

Personal profile

Biography

Dr Senthil Arumugam obtained his PhD training in the lab of Prof Petra Schwille at the Max Planck Institute for Cell Biology and Genetics in Dresden, Germany, focusing on self-organisation of proteins involved in bacterial cell division.His post-doctoral work in the labs of Prof Patricia Bassereau and Prof Ludger Johannes at the Curie Institute, Paris, France, focused on protein-membrane interactions and cellular trafficking.Dr Arumugam joined Single Molecule Science at the University of New South Wales as an independent group leader in September 2016 and established the Lattice Light-Sheet Imaging infrastructure with his research focused on endosomal trafficking.Since October 2019, he is an EMBL Australia Group Leader at the Monash Biomedicine Discovery Institute, with the lab focussing on fundamental questions in intracellular trafficking and their role in cell fate specification and pattern formation in development using LLSM and MOSAIC. 

Research interests

We aim to understand how complex properties arise out of molecules and their interactions, with a primary focus on endosomal trafficking at the level of single cells and in the context of intercellular communications in development. To enable this, we use advanced fluorescence imaging and spectroscopy methods that include Lattice Light Sheets, Adaptive Optics based light sheets, single molecule imaging and other related techniques, complemented by computational data analysis and mathematical modelling. Our broad areas of interests are:

  • Cell biology and developmental biology
  • Advanced fluorescence imaging, optogenetics, image and data analysis
  • Self-organisation, and pattern formation

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 13 - Climate Action
  • SDG 15 - Life on Land
  • SDG 17 - Partnerships for the Goals

Education/Academic qualification

Biophysics, PhD, Reconsitution of Bacterial Cell Division, Max Planck Institut fur molekulare Zellbiologie und Genetik (Max Planck Institute of Molecular Cell Biology and Genetics)

Award Date: 7 Nov 2012

Biophysics, M.Sc, Imaging Somatic Exocytosis in Serotonergic Neurons, Tata Institute of Fundamental Research (TIFR)

Award Date: 30 Jun 2008

Chemistry, B.Sc

Award Date: 30 Jun 2006

Physiology Course - 2011, Marine Biological Laboratory (MBL)

External positions

Group Leader, University of New South Wales (UNSW)

29 Aug 20164 Oct 2019

Visiting Researcher, National Centre for Biological Sciences

1 Jun 20167 Aug 2016

Post doctoral Researcher, L'institut Curie (Curie Institute)

7 Jan 201331 Mar 2016

Research area keywords

  • Biophysics
  • Self-organization and Self-assembly
  • cell biology
  • Imaging Biological Processes
  • Lattice Light Sheet Microscopy
  • Adaptive Optics

Collaborations and top research areas from the last five years

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