20092020
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Research Output 2009 2018

2018
5 Citations (Scopus)

GeNets: a unified web platform for network-based genomic analyses

Li, T., Kim, A., Rosenbluh, J., Horn, H., Greenfeld, L., An, D., Zimmer, A., Liberzon, A., Bistline, J., Natoli, T., Li, Y., Tsherniak, A., Narayan, R., Subramanian, A., Liefeld, T., Wong, B., Thompson, D., Calvo, S., Carr, S., Boehm, J. & 5 others, Jaffe, J., Mesirov, J., Hacohen, N., Regev, A. & Lage, K., 18 Jun 2018, In : Nature Methods. 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
26 Citations (Scopus)

Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression

Rosenbluh, J., Xu, H., Harrington, W., Gill, S., Wang, X., Vazquez, F., Root, D. E., Tsherniak, A. & Hahn, W., 23 May 2017, In : Nature Communications. 8, 8 p., 15403.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016
32 Citations (Scopus)

Characterizing genomic alterations in cancer by complementary functional associations

Kim, J. W., Botvinnik, O. B., Abudayyeh, O., Birger, C., Rosenbluh, J., Shrestha, Y., Abazeed, M. E., Hammerman, P. S., DiCara, D., Konieczkowski, D. J., Johannessen, C. M., Liberzon, A., Alizad-Rahvar, A. R., Alexe, G., Aguirre, A., Ghandi, M., Greulich, H., Vazquez, F., Weir, B. A., Van Allen, E. M. & 15 others, Tsherniak, A., Shao, D. D., Zack, T. I., Noble, M., Getz, G., Beroukhim, R., Garraway, L. A., Ardakani, M., Romualdi, C., Sales, G., Barbie, D. A., Boehm, J. S., Hahn, W. C., Mesirov, J. P. & Tamayo, P., 18 Apr 2016, In : Nature Biotechnology. 34, 5, p. 539-546 8 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Genetic and proteomic interrogation of lower confidence candidate genes reveals signaling networks in β-catenin-active cancers

Rosenbluh, J., Mercer, J., Shrestha, Y., Oliver, R., Tamayo, P., Doench, J. G., Tirosh, I., Piccioni, F., Hartenian, E., Horn, H., Fagbami, L., Root, D. E., Jaffe, J., Lage, K., Boehm, J. S. & Hahn, W. C., 28 Sep 2016, In : Cell Systems. 3, 3, p. 302-316 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014
68 Citations (Scopus)

Genomic insights into WNT/β-catenin signaling

Rosenbluh, J., Wang, X. & Hahn, W. C., Feb 2014, In : Trends in Pharmacological Sciences. 35, 2, p. 103-109 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

319 Citations (Scopus)

KRAS and YAP1 converge to regulate EMT and tumor survival

Shao, D. D., Xue, W., Krall, E. B., Bhutkar, A., Piccioni, F., Wang, X., Schinzel, A. C., Sood, S., Rosenbluh, J., Kim, J. W., Zwang, Y., Roberts, T. M., Root, D. E., Jacks, T. & Hahn, W. C., 3 Jul 2014, In : Cell. 158, 1, p. 171-184 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
167 Citations (Scopus)

RNF43 is frequently mutated in colorectal and endometrial cancers

Giannakis, M., Hodis, E., Mu, X. J., Yamauchi, M., Rosenbluh, J., Cibulskis, K., Saksena, G., Lawrence, M. S., Qian, Z. R., Nishihara, R., Van Allen, E. M., Hahn, W. C., Gabriel, S. B., Lander, E. S., Getz, G., Ogino, S., Fuchs, C. S. & Garraway, L. A., 26 Oct 2014, In : Nature Genetics. 46, 12, p. 1264-1266 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
4 Citations (Scopus)

Erratum: β-catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

Rosenbluh, J., Nijhawan, D., Cox, A. G., Li, X., Neal, J. T., Schafer, E. J., Zack, T. I., Wang, X., Tsherniak, A., Schinzel, A. C., Shao, D. D., Schumacher, S. E., Weir, B. A., Vazquez, F., Cowley, G. S., Root, D. E., Mesirov, J. P., Beroukhim, R., Kuo, C. J., Goessling, W. & 1 others, Hahn, W. C., 28 Mar 2013, In : Cell. 153, 1, p. 267-270 4 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

43 Citations (Scopus)

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers

Hagerstrand, D., Tong, A., Schumacher, S. E., Ilic, N., Shen, R. R., Cheung, H. W., Vazquez, F., Shrestha, Y., Kim, S. Y., Giacomelli, A. O., Rosenbluh, J., Schinzel, A. C., Spardy, N. A., Barbie, D. A., Mermel, C. H., Weir, B. A., Garraway, L. A., Tamayo, P., Mesirov, J. P., Beroukhim, R. & 1 others, Hahn, W. C., Sep 2013, In : Cancer Discovery. 3, 9, p. 1044-1057 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012
114 Citations (Scopus)

Cancer vulnerabilities unveiled by genomic loss

Nijhawan, D., Zack, T. I., Ren, Y., Strickland, M. R., Lamothe, R., Schumacher, S. E., Tsherniak, A., Besche, H. C., Rosenbluh, J., Shehata, S., Cowley, G. S., Weir, B. A., Goldberg, A. L., Mesirov, J. P., Root, D. E., Bhatia, S. N., Beroukhim, R. & Hahn, W. C., 17 Aug 2012, In : Cell. 150, 4, p. 842-854 13 p.

Research output: Contribution to journalArticleResearchpeer-review

270 Citations (Scopus)

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of Telomeres pathway

Lovejoy, C. A., Li, W., Reisenweber, S., Thongthip, S., Bruno, J., de Lange, T., De, S., Petrini, J. H. J., Sung, P. A., Jasin, M., Rosenbluh, J., Zwang, Y., Weir, B. A., Hatton, C., Ivanova, E., Macconaill, L., Hanna, M., Hahn, W. C., Lue, N. F., Reddel, R. R. & 5 others, Jiao, Y., Kinzler, K., Vogelstein, B., Papadopoulos, N. & Meeker, A. K., Jul 2012, In : PLoS Genetics. 8, 7, p. 1-16 16 p., e1002772.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
352 Citations (Scopus)

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

Rosenbluh, J., Nijhawan, D., Cox, A. G., Li, X., Neal, J. T., Schafer, E. J., Zack, T. I., Wang, X., Tsherniak, A., Schinzel, A. C., Shao, D. D., Schumacher, S. E., Weir, B. A., Vazquez, F., Cowley, G. S., Root, D. E., Mesirov, J. P., Beroukhim, R., Kuo, C. J., Goessling, W. & 1 others, Hahn, W. C., 21 Dec 2012, In : Cell. 151, 7, p. 1457-1473 17 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
26 Citations (Scopus)

RMRP is a non-coding RNA essential for early murine development

Rosenbluh, J., Nijhawan, D., Chen, Z., Wong, K-K., Masutomi, K. & Hahn, W. C., Oct 2011, In : PLoS ONE. 6, 10, p. 1-5 5 p., e26270.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2010
8 Citations (Scopus)

BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat

Bugatti, A., Chiodelli, P., Rosenbluh, J., Loyter, A. & Rusnati, M., Jul 2010, In : Antiviral Research. 87, 1, p. 30-39 10 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Integration of HIV-1 DNA is regulated by interplay between viral Rev and cellular LEDGF/p75 proteins

Levin, A., Rosenbluh, J., Hayouka, Z., Friedler, A. & Loyter, A., Jan 2010, In : Molecular Medicine. 16, 1-2, p. 34-44 11 p.

Research output: Contribution to journalArticleResearchpeer-review

134 Citations (Scopus)

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

Wiedemeyer, W. R., Dunn, I. F., Quayle, S. N., Zhang, J., Chheda, M. G., Dunn, G. P., Zhuang, L., Rosenbluh, J., Chen, S., Xiao, Y., Shapiro, G. I., Hahn, W. C. & Chin, L., 22 Jun 2010, In : Proceedings of the National Academy of Sciences. 107, 25, p. 11501-11506 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
20 Citations (Scopus)

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

Levin, A., Armon-Omer, A., Rosenbluh, J., Melamed-Book, N., Graessmann, A., Waigmann, E. & Loyter, A., 5 Dec 2009, In : Retrovirology. 6, 112.

Research output: Contribution to journalArticleResearchpeer-review

Regulating TERT: Location, location, location

Rosenbluh, J., Nijhawan, D. & Hahn, W. C., 15 Oct 2009, In : Cell Cycle. 8, 20, p. 3257 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review