Personal profile
Education/Academic qualification
Epigenetics / Bioinformatics, PhD, Biochemical characterisation of MeCP2 in the brain
7 Mar 2007 → 12 Dec 2017
Award Date: 12 Dec 2017
Research area keywords
- Epigenetics
- Bioinformatics
- Diabetes
- Cardiovascular Disease
- Epilepsy
- DNA Methylation
- RNA-Seq
- Gene Regulation
- Diabetic Complications
- Single Cell Genomics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
Projects
- 1 Curtailed
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Cytosine methylation predicts diabetic nephropathy progression
El-Osta, S. (Primary Chief Investigator (PCI)), Groop, P.-H. (Chief Investigator (CI)), Khurana, I. (Chief Investigator (CI)) & Maxwell, S. S. (Chief Investigator (CI))
1/01/21 → 28/04/23
Project: Research
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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors
Al-Hasani, K., Marikar, S. N., Kaipananickal, H., Maxwell, S., Okabe, J., Khurana, I., Karagiannis, T., Liang, J. J., Mariana, L., Loudovaris, T., Kay, T. & El-Osta, A., 1 Jan 2024, In: Signal Transduction and Targeted Therapy. 9, 1, 14 p., 2.Research output: Contribution to journal › Article › Research › peer-review
Open Access19 Citations (Scopus) -
Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation
Sourris, K. C., Ding, Y., Maxwell, S. S., Al-Sharea, A., Kantharidis, P., Mohan, M., Rosado, C., Penfold, S., Haase, C. G., Xu, Y., Forbes, J. M., Crawford, S. A., Ramm, G., Harcourt, B. E., Jandeleit-Dahm, K. A. M., Advani, A., Murphy, A. J., Timmermann, D. B., Karihaloo, A. & Knudsen, L. B. & 4 others, , Jan 2024, In: Kidney International. 105, 1, p. 132-149 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access91 Citations (Scopus) -
Set7 Methyltransferase and Phenotypic Switch in Diabetic Glomerular Endothelial Cells
Maxwell, S., Okabe, J., Kaipananickal, H., Rodriguez, H., Khurana, I., Al-Hasani, K., Chow, B. S. M., Pitsillou, E., Karagiannis, T. C., Jandeleit-Dahm, K., Ma, R. C. W., Huang, Y., Chan, J. C. N., Cooper, M. E. & El-Osta, A., Jun 2024, In: Journal of the American Society of Nephrology. 35, 6, p. 733-748 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus) -
The Role of Activator Protein-1 Complex in Diabetes-Associated Atherosclerosis: Insights From Single-Cell RNA Sequencing
Khan, A. W., Aziz, M., Sourris, K. C., Lee, M. K. S., Dai, A., Watson, A. M. D., Maxwell, S., Sharma, A., Zhou, Y., Cooper, M. E., Calkin, A. C., Murphy, A. J., Baratchi, S. & Jandeleit-Dahm, K. A. M., Sept 2024, In: Diabetes. 73, 9, p. 1495-1512 18 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus) -
Characterization of K562 cells: uncovering novel chromosomes, assessing transferrin receptor expression, and probing pharmacological therapies
Karagiannis, T. C., Wall, M., Ververis, K., Pitsillou, E., Tortorella, S. M., Wood, P. A., Rafehi, H., Khurana, I., Maxwell, S. S., Hung, A., Vongsvivut, J. & El-Osta, A., Sept 2023, In: Cellular and Molecular Life Sciences. 80, 9, 16 p., 248.Research output: Contribution to journal › Article › Research › peer-review
14 Citations (Scopus)