Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Epigenetics / Bioinformatics, PhD, Biochemical characterisation of MeCP2 in the brain
7 Mar 2007 → 12 Dec 2017
Award Date: 12 Dec 2017
Research area keywords
- Epigenetics
- Bioinformatics
- Diabetes
- Cardiovascular Disease
- Epilepsy
- DNA Methylation
- RNA-Seq
- Gene Regulation
- Diabetic Complications
- Single Cell Genomics
Collaborations and top research areas from the last five years
Projects
- 1 Curtailed
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Cytosine methylation predicts diabetic nephropathy progression
El-Osta, S., Groop, P., Khurana, I. & Maxwell, S. S.
1/01/21 → 28/04/23
Project: Research
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Pharmacological inhibition of human EZH2 can influence a regenerative β-like cell capacity with in vitro insulin release in pancreatic ductal cells
Naina Marikar, S., Al-Hasani, K., Khurana, I., Kaipananickal, H., Okabe, J., Maxwell, S. & El-Osta, A., Dec 2023, In: Clinical Epigenetics. 15, 1, 15 p., 101.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes
Khurana, I., Kaipananickal, H., Maxwell, S., Birkelund, S., Syreeni, A., Forsblom, C., Okabe, J., Ziemann, M., Kaspi, A., Rafehi, H., Jørgensen, A., Al-Hasani, K., Thomas, M. C., Jiang, G., Luk, A. O., Lee, H. M., Huang, Y., Thewjitcharoen, Y., Nakasatien, S., Himathongkam, T., & 12 others , 15 Feb 2023, In: The Journal of Clinical Investigation. 133, 4, 19 p., e160959.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor
Al-Hasani, K., Khurana, I., Mariana, L., Loudovaris, T., Maxwell, S., Harikrishnan, K. N., Okabe, J., Cooper, M. E. & El-Osta, A., 22 Jul 2022, In: Signal Transduction and Targeted Therapy. 7, 1, 9 p., 248.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Intestinal microbiota regulates diabetes and cancer progression by IL-1β and NOX4 dependent signaling cascades
Noureldein, M., Nawfal, R., Bitar, S., Maxwell, S. S., Khurana, I., Kassouf, H. K., Khuri, F. R., El-Osta, A. & Eid, A. A., Sept 2022, In: Cellular and Molecular Life Sciences. 79, 9, 18 p., 502.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms
Royce, S. G., Licciardi, P. V., Beh, R. C., Bourke, J. E., Donovan, C., Hung, A., Khurana, I., Liang, J. J., Maxwell, S., Mazarakis, N., Pitsillou, E., Siow, Y. Y., Snibson, K. J., Tobin, M. J., Ververis, K., Vongsvivut, J., Ziemann, M., Samuel, C. S., Tang, M. L. K., El-Osta, A., & 1 others , Nov 2022, In: Cellular and Molecular Life Sciences. 79, 11, 22 p., 579.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus)