Projects per year
Personal profile
Biography
Dr Sathiya Maran has completed her Post-doctoral Fellowship in Human Genetics and Data Sciences from Perdana University in 2019. She obtained her Doctor of Philosophy (Human Genetics) and Master of Science (Human Genetics) from the Universiti Sains Malaysia. In 2015, she was awarded the “Chen Student Travel’ award for an outstanding research at the 11th Asia Pacific Conference on Human Genetics held in Vietnam. In 2011, she was conferred with an internship for Genome-Wide Association Study Data Analysis at the Chinese Academy of Science-Max Planck-Gesellschaft (CAS-MPG) Partner Institute, China. Currently she is an active member of the 1Malaysia Human Genome Variome Consortium and she was one of the members of the organizing committee for the launching of the Malaysian node of the Human Variome Project. Her fields of interest are Molecular Medicine & Human Genetics and Computational & system biology. Her research interests are genetics and environmental influence towards the frequency and severity of diseases in humans. She also focuses in next-generation genomic tools to capture genetic determinants, understanding molecular mechanisms and exploring potential biomarkers and advanced personalized medicine associated with non-communicable diseases.
Research interests
Genetic variations and human diseases
To understand how genes are inherited, modified and expressed. To elucidate genotype-phenotype distinctions in defining potential biomarkers and causative mechanisms of non-communicable diseases; focusing in cardiovascular diseases and Helicobacter pylori infection.
Clinical next-generation sequencing and bioinformatics
Employing high-throughput approaches such as SNP genotyping arrays and resequencing to catalog genetic variants. Perform downstream bioinformatics analysis to detect the clinically relevant structural genomic alterations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Human Genetics, PhD, Molecular genetics analysis of MYH3 gene and chromosome 22q11.2 deletion among atrial septal defect patients, Hospital Universiti Sains Malaysia (HUSM) (University Science Hosptial Malaysia)
Award Date: 1 Sept 2017
Collaborations and top research areas from the last five years
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Understanding the role on myosin heavy chains (MYH) in congenital heart defects (CHDs): An integrated in-silico analysis and CRISPR/Cas9 gene-editing approach
Maran, S. (Primary Chief Investigator (PCI)), Kooi Yeong, K. (Chief Investigator (CI)), Hing, G. B. (Chief Investigator (CI)), Ayub, Q. (Chief Investigator (CI)), Khan, M. A. (Chief Investigator (CI)) & sivalingam, S. (Chief Investigator (CI))
1/09/22 → 28/02/26
Project: Research
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X-temp: Pharm-D X-temp stability studies project
Molugulu, N. (Primary Chief Investigator (PCI)), Nair, R. S. (Chief Investigator (CI)), Sundralingam, U. (Chief Investigator (CI)) & Maran, S. (Chief Investigator (CI))
1/06/23 → 30/04/24
Project: Consultancy
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Avocado Fruit and Leaf Bioactive Phytochemicals and Cosmeceutical Applications: A Scoping Review
Yeoh, L. L., Lee, X. N., Lee, W. Y., Goh, B. H. & Sathiya, M., 2024, In: Journal of Pharmacy. 4, 2, p. 186-208 23 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
Current guidelines, challenges and future recommendations for regulation of stem cell research and therapy: a commentary
Wong, R. S. Y., Maran, S. & Goh, B. H., Aug 2024, In: Cytotherapy. 26, 8, p. 785-789 5 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
Functionalization of poly (lactic-co-glycolic acid) nano‑calcium sulphate and fucoidan 3D scaffold using human bone marrow mesenchymal stromal cells for bone tissue engineering application
Shaz, N., Maran, S., Genasan, K., Choudhary, R., Alias, R., Swamiappan, S., Kamarul, T. & Raghavendran, H. R. B., Jan 2024, In: International Journal of Biological Macromolecules. 256, 13 p., 128059.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus) -
In-silico identification of deleterious nonsynonymous SNPs of TBX1 gene: Functional and structural impact towards 22q11.2DS
Almakhari, M., Chen, Y., Kong, A. S. Y., Moradigaravand, D., Lai, K. S., Lim, S. H. E., Loh, J. Y. & Maran, S., Jun 2024, In: PLoS ONE. 19, 6, 13 p., e0298092.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Navigating the interplay between BCL-2 family proteins, apoptosis, and autophagy in colorectal cancer
Kong, A. S. Y., Maran, S. & Loh, H. S., Oct 2024, In: Advances in Cancer Biology - Metastasis. 11, 9 p., 100126.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)
Prizes
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Gold Award : INNOVATION IN BONE IMPLANT: NO MORE SECOND SURGERY AFTER BONE TRANSPLANTATION
Maran, Sathiya (Recipient), 2024
Prize: Prize (including medals and awards)
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Activities
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Pulse of Hope : Congenital Heart Defect Awareness Day 2025
Maran, S. (Contributor), Sekar, M. (Contributor) & Yeo, W. W. Y. (Contributor)
15 Feb 2025Activity: Community Talks, Presentations, Exhibitions and Events › Collaboration on community projects
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Pulse of Hope
Maran, S. (Organiser), Sekar, M. (Organiser), Yeo, W. W. Y. (Member of programme committee) & Lee, S. W. H. (Invited speaker)
15 Feb 2025Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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ONE-DAY WORKSHOP: Hands-On Training and Interpretation of Molecular Docking Using Open-Source MzDOCK Software
Sekar, M. (Organiser) & Maran, S. (Organiser)
30 Jun 2025Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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Molecular Docking and MD simulation using open source software
Maran, S. (Member of programme committee), Sekar, M. (Organiser) & Prabhakaran, P. (Invited speaker)
25 Nov 2024 → 26 Nov 2024Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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School of Pharmacy’s 15th Anniversary celebration
Sathiya Maran (Member of programme committee)
27 Sept 2024Activity: Participating in or organising an event types › Contribution to workshop, seminar, course