Sarah Lockie


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Personal profile


Sarah completed her PhD in 2012 with joint supervision between Monash University, Australia and the University of Cincinnati, OH, USA. She has published on a number of aspects of metabolic homeostasis in mice, including neural control of feeding, ghrelin resistance in obesity, efficacy and side effects of antiobesity drugs, central control of brown adipose tissue thermogenesis, and reward pathway control of feeding and motivation. Her current research interest are focused on loss of appetite in conditions such as cancer cachexia, and severe food avoidance, and how hunger-regulating circuits interact with higher order brain areas to control  functions such as memory, motivation and mood-related behaviours. She heads the Appetite and Behavioural Control Group within the Metabolism, Diabetes and Obesity theme in the Monash Biomedicine Discovery Institute. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy

Research area keywords

  • Metabolic neuroscience
  • endocannabinoids
  • obesity
  • glucose metabolism
  • ghrelin
  • AgRP neurons
  • GFRAL neurons
  • GDF15
  • Cancer cachexia
  • Anxiety
  • GLP-1
  • Glucagon
  • Hypothalamus
  • Ventral tegmental area

Collaborations and top research areas from the last five years

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