Projects per year
Personal profile
Biography
Sarah completed her PhD in 2012 with joint supervision between Monash University, Australia and the University of Cincinnati, OH, USA. She has published on a number of aspects of metabolic homeostasis in mice, including neural control of feeding, ghrelin resistance in obesity, efficacy and side effects of antiobesity drugs. Her current research interest are focused on loss of appetite in cancer cachexia.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Metabolic neuroscience
- endocannabinoids
- obesity
- glucose metabolism
- ghrelin
- AgRP neurons
- GFRAL neurons
- GDF15
- Cancer cachexia
- Anxiety
- GLP-1
- Glucagon
- Hypothalamus
- Ventral tegmental area
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting the brain and sympathetic nervous system to improve outcomes in cancer cachexia
Lockie, S. (Primary Chief Investigator (PCI)), Walton, K. (Associate Investigator (AI)), Andrews, Z. (Associate Investigator (AI)), Stark, R. (Associate Investigator (AI)), Oldfield, B. (Associate Investigator (AI)), Sloan, E. (Associate Investigator (AI)) & Gregorevic, P. (Associate Investigator (AI))
1/01/22 → 31/12/25
Project: Research
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NHMRC Equipment Grant - Danish Myo-Technology Organ Bath 820MO and electrical stimulator
Rose, A. (Primary Chief Investigator (PCI)), Mitchell, C. (Chief Investigator (CI)), Tiganis, T. (Chief Investigator (CI)), Mcgrath, M. (Chief Investigator (CI)), Lockie, S. (Chief Investigator (CI)), Harrison, C. (Chief Investigator (CI)) & Eynon, N. (Chief Investigator (CI))
1/11/23 → 31/12/24
Project: Research
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Endocrine Society of Australia Post Doctoral Award
Lockie, S. (Primary Chief Investigator (PCI))
1/03/20 → 28/02/21
Project: Research
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BSN Research visit grant
Lockie, S. (Primary Chief Investigator (PCI)) & Clarke, R. (Associate Investigator (AI))
14/01/19 → 31/12/19
Project: Other
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The Neurocircuitry of Food Choice in Obesity
Verdejo-Garcia, A. (Primary Chief Investigator (PCI)), Andrews, Z. (Chief Investigator (CI)), Lockie, S. (Chief Investigator (CI)) & Harding, I. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/18 → 31/12/21
Project: Research
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Ghrelin and LEAP2: Subtle Players in Cachexia, Essential for the Bigger Picture
Lockie, S. H. (Leading Author) & Hagg, A., Jul 2025, In: Endocrinology. 166, 7, 2 p., bqaf093.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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Stress relief of chemo illness
Rose, A. J. & Lockie, S. H., 6 May 2024, In: Journal of Experimental Medicine. 221, 7, 3 p., e20240545.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
Acute inhibition of hunger-sensing AgRP neurons promotes context-specific learning in mice
Reed, F., Reichenbach, A., Dempsey, H., Clarke, R. E., Mequinion, M., Stark, R., Rawlinson, S., Foldi, C. J., Lockie, S. H. & Andrews, Z. B., Nov 2023, In: Molecular Metabolism. 77, 13 p., 101803.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity
So, W. L., Hu, J., Jeffs, L., Dempsey, H., Lockie, S. H., Zigman, J. M., Stark, R., Reichenbach, A. & Andrews, Z. B., Dec 2023, In: Molecular Metabolism. 78, 11 p., 101826.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
Identification of a Stress-Sensitive Anorexigenic Neurocircuit From Medial Prefrontal Cortex to Lateral Hypothalamus
Clarke, R. E., Voigt, K., Reichenbach, A., Stark, R., Bharania, U., Dempsey, H., Lockie, S. H., Mequinion, M., Lemus, M., Wei, B., Reed, F., Rawlinson, S., Nunez-Iglesias, J., Foldi, C. J., Kravitz, A. V., Verdejo-Garcia, A. & Andrews, Z. B., 15 Feb 2023, In: Biological Psychiatry. 93, 4, p. 309-321 13 p.Research output: Contribution to journal › Article › Research › peer-review
9 Citations (Scopus)
Prizes
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Harold Mitchell ECR travel fellowship
Lockie, Sarah (Recipient), 2 Aug 2018
Prize: Prize (including medals and awards)
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Vice Chancellor's Commendation for Doctoral Thesis Excellence
Lockie, S. (Recipient), 6 Dec 2012
Prize: Prize (including medals and awards)
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Young Investigator Prize
Lockie, S. (Recipient), 15 Sept 2015
Prize: Prize (including medals and awards)
Press/Media
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So you think you can pitch? competition
Payne, J., Ramarathinam, S., Lockie, S. & Chakraborty, A.
16/12/20
1 item of Media coverage
Press/Media: Article/Feature