Projects per year
Sarah completed her PhD in 2012 with joint supervision between Monash University, Australia and the University of Cincinnati, OH, USA. She has published on a number of aspects of metabolic homeostasis in mice, including neural control of feeding, ghrelin resistance in obesity, efficacy and side effects of antiobesity drugs, central control of brown adipose tissue thermogenesis, and reward pathway control of feeding and motivation. Her current research interest are focused on loss of appetite in conditions such as cancer cachexia, and severe food avoidance, and how hunger-regulating circuits interact with higher order brain areas to control functions such as memory, motivation and mood-related behaviours. She heads the Appetite and Behavioural Control Group within the Metabolism, Diabetes and Obesity theme in the Monash Biomedicine Discovery Institute.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Metabolic neuroscience
- glucose metabolism
- AgRP neurons
- GFRAL neurons
- Cancer cachexia
- Ventral tegmental area
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Marks, D., Lockie, S., Grossberg, A., Habecker, B. & Zhu, X.
10/09/21 → 31/08/26
1/03/20 → 28/02/21
Reed, F., Lockie, S. H., Reichenbach, A., Foldi, C. J. & Andrews, Z. B., Jun 2022, In: Current Opinion in Endocrine and Metabolic Research. 24, 13 p., 100337.
Research output: Contribution to journal › Review Article › Research › peer-review
Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in HumansHornsby, A. K. E., Buntwal, L., Carisi, M. C., Santos, V. V., Johnston, F., Roberts, L. D., Sassi, M., Mequinion, M., Stark, R., Reichenbach, A., Lockie, S. H., Siervo, M., Howell, O., Morgan, A. H., Wells, T., Andrews, Z. B., Burn, D. J. & Davies, J. S., 20 Oct 2020, In: Cell Reports Medicine. 1, 7, p. 1-e9 23 p., 100120.
Research output: Contribution to journal › Article › Research › peer-reviewOpen Access
AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient PartitioningReichenbach, A., Stark, R., Mequinion, M., Denis, R. R. G., Goularte, J. F., Clarke, R. E., Lockie, S. H., Lemus, M. B., Kowalski, G. M., Bruce, C. R., Huang, C., Schittenhelm, R. B., Mynatt, R. L., Oldfield, B. J., Watt, M. J., Luquet, S. & Andrews, Z. B., 13 Feb 2018, In: Cell Reports. 22, 7, p. 1745-1759 15 p.
Research output: Contribution to journal › Article › Research › peer-reviewOpen AccessFile
Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restrictionReichenbach, A., Stark, R., Mequinion, M., Lockie, S. H., Lemus, M. B., Mynatt, R. L., Luquet, S. & Andrews, Z. B., 1 Dec 2018, In: The FASEB Journal. 32, 12, p. 6923-6933 11 p.
Research output: Contribution to journal › Article › Research › peer-review
Lockie, Sarah (Recipient), 6 Dec 2012
Prize: Prize (including medals and awards)