Sarah Lockie

Dr

Accepting PhD Students

PhD projects

https://supervisorconnect.med.monash.edu/projects/behavioural-phenotyping-gfral-neurons-mood-and-motivation https://supervisorconnect.med.monash.edu/projects/neural-control-metabolism-cancer-cachexia-syndrome

20092020

Research activity per year

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Personal profile

Biography

Sarah completed her PhD in 2012 with joint supervision between Monash University, Australia and the University of Cincinnati, OH, USA. She has published on a number of aspects of metabolic homeostasis in mice, including neural control of feeding, ghrelin resistance in obesity, efficacy and side effects of antiobesity drugs, central control of brown adipose tissue thermogenesis, and reward pathway control of feeding and motivation. Her current research interest are focused on loss of appetite in conditions such as cancer cachexia, and severe food avoidance, and how hunger-regulating circuits interact with higher order brain areas to control  functions such as memory, motivation and mood-related behaviours. She heads the Appetite and Behavioural Control Group within the Metabolism, Diabetes and Obesity theme in the Monash Biomedicine Discovery Institute. 

Research area keywords

  • Metabolic neuroscience
  • endocannabinoids
  • obesity
  • glucose metabolism
  • ghrelin
  • AgRP neurons
  • GFRAL neurons
  • GDF15
  • Cancer cachexia
  • Anxiety
  • GLP-1
  • Glucagon
  • Hypothalamus
  • Ventral tegmental area

Network

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