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Personal profile

Research interests

My research investigates mechanisms of autoimmune disease development, with particular emphasis on relevance in the clinic and translation towards treatments. I am especially interested in the regulation of B cells, including the formation of germinal centres, memory B cells and plasma cells in response to immunisation and in the setting of B cell-mediated autoimmunity, particularly lupus. I am also interested in the influences of innate immune mechanisms on the development and progression of autoimmune diseases.


I undertook my PhD at the Walter and Eliza Hall Institute of Medical Research, studying the mechanisms that drive autoimmune disease, particularly B cell and plasma cell devloment and behaviour. I then took a postdoctoral position at Harvard Medical School where I used multiphoton microscopy to visualise these events. Following this I moved to Trinity College Dublin, where I studied mechanisms of innate immunity that are helpful, or harmful, in inflammatory bowel disease. I was then recruited to Monash University where we now study how innate and adaptive immunity intersect to drive autoimmune diseases, particularly lupus.

Supervision interests

I am currently supervising PhD, Honours and BMedSci students - please contact me if you are interested in joining our group.

Clinical activities

I am a lecturer in a 3rd year Clinical Immunopathology Unit, Monash University


Scientific consultant, editor and lead author, Nelson Cengage Learning

Produced three senior biology textbooks:

  • Biology for the Australian Curriculum, Units 3 and 4 (released in Australia and New Zealand)
  • Biology for the Victorian Certificate of Education, Units 1 and 2
  • Biology for the Victorian Certificate of Education, Units 3 and 4

Community service

  • 2014-ongoing: Science Teachers Association of Victoria VCE Biology conference: I deliver annual educational sessions for senior biology teachers and distributed teaching resources for use by teachers and students. I continue to act as a consultant to teachers.
  • Ongoing: I have had many volunteer roles with multiple outreach programs targeting senior secondary school students and teachers including the Research Australia Youth Ambassador program


  • Immunology
  • Autoimmune Diseases
  • Inflammation
  • Adaptive immunity
  • Systemic Lupus Erythematosus
  • Clinical translation
  • Drug discovery
  • Vaccine design
  • Germinal centre reaction
  • Antibodies
  • Autoantibodies
  • B cells
  • Plasma cells
  • T cells
  • Th17 cells
  • Autophagy

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2018

Research Output 2009 2016

  • 18 Article
  • 1 Chapter (Book)
  • 1 Meeting Abstract
  • 1 Review Article

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling

Ní Cheallaigh, C., Sheedy, F. J., Harris, J., Muñoz-Wolf, N., Lee, J., West, K., McDermott, E. P., Smyth, A., Gleeson, L. E., Coleman, M., Martinez, N., Hearnden, C. H. A., Tynan, G. A., Carroll, E. C., Jones, S. A., Corr, S. C., Bernard, N. J., Hughes, M. M., Corcoran, S. E., O'Sullivan, M. & 7 othersFallon, C. M., Kornfeld, H., Golenbock, D., Gordon, S. V., O'Neill, L. A. J., Lavelle, E. C. & Keane, J., 16 Feb 2016, In : Immunity. 44, 2, p. 368-379 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus

Jones, S. A., Toh, A. E. J., Odobasic, D., Oudin, M-A. V., Cheng, Q., Lee, J. P. W., White, S. J., Russ, B. E., Infantino, S., Light, A., Tarlinton, D. M., Harris, J. & Morand, E. F., 2016, In : Annals of the Rheumatic Diseases. 75, 4, p. 739-747 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Glucocorticoids in 2015: New answers to old problems

Jones, S. A. & Morand, E. F., Feb 2016, In : Nature Reviews Rheumatology. 12, 2, p. 73-74 2 p.

Research output: Contribution to journalArticleOtherpeer-review

Loss of autophagy enhances MIF/macrophage migration inhibitory factor release by macrophages

Lee, J. P. W., Foote, A., Fan, H., Peral de Castro, C., Lang, T., Jones, S. A., Gavrilescu, N., Mills, K. H. G., Leech, M., Morand, E. F. & Harris, J., 2 Jun 2016, In : Autophagy. 12, 6, p. 907 - 916 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Autophagy Controls the Production and Secretion of IL-1β: Underlying Mechanisms

Peral de Castro, C., Jones, S. A. & Harris, J., 2015, Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Hayat, M. A. (ed.). Amsterdam: Elsevier, Vol. 6. p. 201-209 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review