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    Australia

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20082021
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Research Output 2008 2019

  • 18 Article
  • 2 Abstract
  • 1 Encyclopaedia / Dictionary Entry
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Article
2019

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

Heaton, S. M., Atkinson, S. C., Sweeney, M. N., Yang, S. N. Y., Jans, D. A. & Borg, N. A., 30 Sep 2019, In : Cells. 8, 10, 22 p., 1181.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

Yang, S. N. Y., Atkinson, S. C., Fraser, J. E., Wang, C., Maher, B., Roman, N., Forwood, J. K., Wagstaff, K. M., Borg, N. A. & Jans, D. A., 24 Mar 2019, In : Cells. 8, 3, 15 p., 281.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018
3 Citations (Scopus)

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus v

Atkinson, S. C., Audsley, M. D., Lieu, K. G., Marsh, G. A., Thomas, D. R., Heaton, S. M., Paxman, J. J., Wagstaff, K. M., Buckle, A. M., Moseley, G. W., Jans, D. A. & Borg, N. A., 10 Jan 2018, In : Scientific Reports. 8, 1, 17 p., 358.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target

Atkinson, S. C., Dogovski, C., Wood, K., Griffin, M. D. W., Gorman, M. A., Hor, L., Reboul, C. F., Buckle, A. M., Wuttke, J., Parker, M. W., Dobson, R. C. J. & Perugini, M. A., 3 Jul 2018, In : Structure. 26, 7, p. 948-959 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
2 Citations (Scopus)

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase

Donovan, K. A., Atkinson, S. C., Kessans, S. A., Peng, F., Cooper, T. F., Griffin, M. D. W., Jameson, G. B. & Dobson, R. C. J., 1 Apr 2016, In : Acta Crystallographica Section D: Structural Biology. D72, Part 4, p. 512-519 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2015
21 Citations (Scopus)

The Anopheles-midgut APN1 structure reveals a new malaria transmission-blocking vaccine epitope

Atkinson, S. C., Armistead, J. S., Mathias, D. K., Sandeu, M. M., Tao, D., Borhani-Dizaji, N., Tarimo, B. B., Morlais, I., Dinglasan, R. R. & Borg, N. A., 2015, In : Nature Structural and Molecular Biology. 22, 7, p. 532 - 539 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
12 Citations (Scopus)

Identification of the bona fide DHDPS from a common plant pathogen

Atkinson, S. C., Hor, L., Dogovski, C., Dobson, R. C. J. & Perugini, M. A., Sep 2014, In : Proteins: Structure, Function, and Bioinformatics. 82, 9, p. 1869-1883 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
8 Citations (Scopus)

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus

North, R. A., Kessans, S. A., Atkinson, S., Suzuki, H., Watson, A. J. A., Burgess, B. R., Angley, L. M., Hudson, A. O., Varsani, A., Griffin, M. DW., Fairbanks, A. J. & Dobson, R. C. J., 2013, In : Acta Crystallographica. Section F: Structural Biology Communications. 69, 3, p. 306 - 312 7 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition

Atkinson, S. C., Dogovski, C., Downton, M. T., Czabotar, P. E., Dobson, R. C. J., Gerrard, J. A., Wagner, J. & Perugini, M. A., 2013, In : Plant Molecular Biology. 81, 4-5, p. 431-446 16 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
29 Citations (Scopus)

Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana

Griffin, M. D. W., Billakanti, J. M., Wason, A., Keller, S., Mertens, H. D. T., Atkinson, S. C., Dobson, R. C. J., Perugini, M. A., Gerrard, J. A. & Pearce, F. G., 5 Jul 2012, In : PLoS ONE. 7, 7, 12 p., e40318.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens

Atkinson, S. C., Dogovski, C., Dobson, R. C. J. & Perugini, M. A., 2012, In : Acta Crystallographica. Section F: Structural Biology Communications. 68, 9, p. 1040-1047 8 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine

Atkinson, S. C., Dogovski, C., Downton, M. T., Pearce, F. G., Reboul, C. F., Buckle, A. M., Gerrard, J. A., Dobson, R. CJ., Wagner, J. & Perugini, M. A., 2012, In : PLoS ONE. 7, 6, 9 p., e38318.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
19 Citations (Scopus)

X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP

Kannan Sivaraman, K., Oellig, C. A., Huynh, K., Atkinson, S. C., Poreba, M., Perugini, M. A., Trenholme, K. R., Gardiner, D. L., Salvesen, G. S., Drag, M., Dalton, J. P., Whisstock, J. C. & McGowan, S., 2012, In : Journal of Molecular Biology. 422, 4, p. 495 - 507 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
10 Citations (Scopus)

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera

Atkinson, S. C., Dogovski, C., Newman, J., Dobson, R. C. J. & Perugini, M. A., 2011, In : Acta Crystallographica. Section F: Structural Biology Communications. 67, 12, p. 1537-1541 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
38 Citations (Scopus)

Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax

Voss, J. E., Scally, S. W., Taylor, N. L., Atkinson, S. C., Griffin, M. D. W., Hutton, C. A., Parker, M. W., Alderton, M. R., Gerrard, J. A., Dobson, R. C. J., Dogovski, C. & Perugini, M. A., 2010, In : Journal of Biological Chemistry. 285, 8, p. 5188-5195 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
13 Citations (Scopus)

Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate

Atkinson, S. C., Dobson, R. C. J., Newman, J. M., Gorman, M. A., Dogovski, C., Parker, M. W. & Perugini, M. A., 2009, In : Acta Crystallographica. Section F: Structural Biology Communications. 65, 3, p. 253-255 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
75 Citations (Scopus)

Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen

Burgess, B. R., Dobson, R. CJ., Bailey, M. F., Atkinson, S. C., Griffin, M. DW., Jameson, G. B., Parker, M. W., Gerrard, J. & Perugini, M. A., 2008, In : Journal of Biological Chemistry. 283, 41, p. 27598 - 27603 6 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum

Dobson, R. CJ., Atkinson, S. C., Gorman, M. A., Newman, J., Parker, M. W. & Perugini, M. A., 2008, In : Acta Crystallographica. Section F: Structural Biology Communications. 64, 3, p. 206-208 3 p.

Research output: Contribution to journalArticleResearchpeer-review