20082020

Research output per year

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Personal profile

Biography

Dr Sarah Atkinson is a structural biologist and biophysicist focusing on how protein-protein interactions impact the catalytic activity, conformation/shape and oligomerisation of enzymes essential for a variety of biological processes. In particular, she has a keen interest in the use of structural biology to understand the innate immune response and characterise novel viral targets.

 

Following the completion of her PhD at The University of Melbourne in 2013, Dr Atkinson began working with Dr Natalie Borg in the Department of Biochemistry & Molecular Biology at Monash University as a NHMRC Early Career Fellow (2014-2017) and a FMNHS Senior Research Fellow (2018). She currently holds an ARC DECRA Fellowship (2019-2021).

Research interests

Innate Immunity, Host-virus interactions, Ubiquitination, protein-protein interactions, Structural biology, X-ray crystallography, Small Angle X-ray Scattering, Analytical Ultracentrifugation.

Community service

Biomedicine Discovery Institute Early Career Researchers Committee (2018 - 2020)

  • Chair, career development workshop sub-committee (2019)

Education/Academic qualification

Biochemistry and Molecular Biology, PhD, University of Melbourne

Award Date: 14 Dec 2013

External positions

Monash University representative, Melbourne Protein Group (MPG)

20172020

Research area keywords

  • Structural Biology
  • Immunity
  • Biophysics
  • Enzymes
  • Protein-Protein Interactions
  • Crystallography
  • Small Angle X-Ray Scattering
  • Analytical Ultracentrifugation

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Projects

Research Output

  • 20 Article
  • 2 Abstract
  • 1 Encyclopaedia / Dictionary Entry

RK-33 Is a Broad-Spectrum Antiviral Agent That Targets DEAD-Box RNA Helicase DDX3X

Yang, S. N. Y., Atkinson, S. C., Audsley, M. D., Heaton, S. M., Jans, D. A. & Borg, N. A., 9 Jan 2020, In : Cells. 9, 1, 13 p., 170.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer

Yang, S. N. Y., Atkinson, S. C., Wang, C., Lee, A., Bogoyevitch, M. A., Borg, N. A. & Jans, D. A., May 2020, In : Antiviral Research. 177, 9 p., 104760.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

Heaton, S. M., Atkinson, S. C., Sweeney, M. N., Yang, S. N. Y., Jans, D. A. & Borg, N. A., 30 Sep 2019, In : Cells. 8, 10, 22 p., 1181.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

Yang, S. N. Y., Atkinson, S. C., Fraser, J. E., Wang, C., Maher, B., Roman, N., Forwood, J. K., Wagstaff, K. M., Borg, N. A. & Jans, D. A., 24 Mar 2019, In : Cells. 8, 3, 15 p., 281.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus v

Atkinson, S. C., Audsley, M. D., Lieu, K. G., Marsh, G. A., Thomas, D. R., Heaton, S. M., Paxman, J. J., Wagstaff, K. M., Buckle, A. M., Moseley, G. W., Jans, D. A. & Borg, N. A., 10 Jan 2018, In : Scientific Reports. 8, 1, 17 p., 358.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Prizes

ARC DECRA Fellowship

Atkinson, Sarah (Recipient), 2019

Prize: Competitive Fellowships

Beckman Coulter Postdoctoral Travel Award

Atkinson, Sarah (Recipient), 2019

Prize: Prize (including medals and awards)

Biomedicine Discovery Institute Travel Award

Atkinson, Sarah (Recipient), 2017

Prize: Prize (including medals and awards)

Monash University Faculty of Medicine Fellows Publication Prize

Atkinson, Sarah (Recipient), 2016

Prize: Prize (including medals and awards)