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Sanja Bosnyak-Gladovic

Dr

20102019
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Research Output 2010 2019

2019

AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: Impact on the therapeutic targeting of renal and cardiac fibrosis

Chow, B. S. M., Kocan, M., Shen, M., Wang, Y., Han, L., Chew, J. Y., Wang, C., Bosnyak, S., Mirabito-Colafella, K. M., Barsha, G., Wigg, B., Johnstone, E. K. M., Hossain, M. A., Pfleger, K. D. G., Denton, K. M., Widdop, R. E., Summers, R. J., Bathgate, R. A. D., Hewitson, T. D. & Samuel, C. S., Sep 2019, (Accepted/In press) In : Journal of the American Society of Nephrology. 30, 9, 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Isoform-specific biased agonism of histamine H3 receptor agonists

Riddy, D. M., Cook, A. E., Diepenhorst, N. A., Bosnyak, S., Brady, R., La Cour, C. M., Mocaer, E., Summers, R. J., Charman, W. N., Sexton, P. M., Christopoulos, A. & Langmead, C. J., 1 Feb 2017, In : Molecular Pharmacology. 91, 2, p. 87-99 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Isoform-specific bias of histamine H3 receptor agonists

Riddy, D., Cook, A. E., Diepenhorst, N., Bosnyak, S., Brady, R., La Cour, C. M., Mocaer, E., Summers, R., Charman, W., Sexton, P. M., Christopoulos, A. & Langmead, C., 2016.

Research output: Contribution to conferencePosterOtherpeer-review

2015

beta-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats

Del Borgo, M. P., Wang, Y., Bosnyak, S., Walters, P. E., Spizzo, I., Perlmutter, P., Hilliard, L. M., Denton, K. M., Aguilar, M-I. M., Widdop, R. E. & Jones, E. S., 2015, In : Clinical Science. 129, 6, p. 505 - 513 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II

Magnani, F., Pappas, C. G., Crook, T., Magafa, V., Cordopatis, P. A., Ishiguro, S., Ohta, N., Selent, J., Bosnyak, S., Jones, E. S., Gerothanassis, I. P., Tamura, M., Widdop, R. E. & Tzakos, A. G., 2014, In : ACS Chemical Biology. 9, 7, p. 1420 - 1425 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis

Chow, B. SM., Kocan, M., Bosnyak, S., Sarwar, M., Wigg, B., Jones, E. S., Widdop, R. E., Summers, R. J., Bathgate, R. A. D., Hewitson, T. D. & Samuel, C. S., 2014, In : Kidney International. 86, 1, p. 75 - 85 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Use of hemi-equilibrium to determine the dissociation kinetics of histamine H3 receptor antagonists.

Bosnyak, S., Riddy, D., Cook, A. E., Diepenhorst, N., Sexton, P. M., Christopoulos, A. & Langmead, C., 2014. 1 p.

Research output: Contribution to conferencePosterOtherpeer-review

2013

Direct AT{2} receptor stimulation is athero-protective and stabilizes plaque in Apolipoprotein E-deficient mice

Tesanovic Kljajic, S., Widdop, R. E., Vinh, A., Welungoda, I. K., Bosnyak, S., Jones, E. S. & Gaspari, T. A., 2013, In : International Journal of Cardiology. 169, 4, p. 281 - 287 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Differential mechanisms of ang (1-7)-mediated vasodepressor effect in adult and aged candesartan-treated rats

Bosnyak, S., Widdop, R. E., Denton, K. M. & Jones, E. S., 2012, In : International Journal of Hypertension. 2012, Art. No.192567, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2011

A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function

Jones, E. S., Del Borgo, M. P., Kirsch, J., Clayton, D. J., Bosnyak, S., Welungoda, I. K., Hausler, N., Unabia, S., Perlmutter, P., Thomas, W. G., Aguilar, M. I. & Widdop, R. E., 2011, In : Hypertension. 57, 3, p. 570 - 576 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors

Bosnyak, S., Jones, E., Christopoulos, A., Aguilar, M., Thomas, W. & Widdop, R., 2011, In : Clinical Science. 121, 7, p. 297 - 303 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats

Bosnyak, S., Welungoda, I. K., Hallberg, A., Alterman, M., Widdop, R. E. & Jones, E. S., 2010, In : British Journal of Pharmacology. 159, 3, p. 709 - 716 8 p.

Research output: Contribution to journalArticleResearchpeer-review