Projects per year
Personal profile
Biography
Sam's work combines microbiology, immunology and computational analysis to understand the functional role and community dynamics of the human microbiota in health and disease.
Understanding how our microbiota is acquired and the forces that cause it to change provides important insights into health and disease. Sam's research seeks to understand the relationship between host state, microbiota community and the susceptibility to diseases including infections by opportunistic pathogens such as Clostridium difficile and Inflammatory Bowel Disease. His research is focused on:
- Analysis of the diversity of host cellular and transcriptional responses using in-vitro and in-vivo models of human microbiota communities
- Wide scale 16S profiling and metagenomic sequence based analysis to understand microbiota community structure
- Computational modeling and machine learning based approaches to understand microbiota community dynamics in health and dysbiotic disease
This work ultimately seeks to provide novel bacteriotherapies and identify other therapeutic interventions to improve human health
Keywords
- Microbiota
- Metagenomics
- Systems Biology
- Innate Immunity
- microRNA
- Interferon
- Bioinformatics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2023
Unravelling the role of type I Interferon family in human infectious and inflammatory diseases
Hertzog, P. J., Casanova, J., Netea, M. G., Turner, S. J., Creek, D. J., Gearing, J., Croft, N. P., Forster, S. & Polo, J. M.
National Health & Medical Research Council (NHMRC)
1/01/19 → 31/12/23
Project: Research
Characterisation of mobile antimicrobial resistance in the human gastrointestinal microbiota
Forster, S., Costello, S. & Lawley, T. D.
National Health & Medical Research Council (NHMRC)
1/01/19 → 31/12/22
Project: Research
Research Output 2009 2018
A new piece in the microbiome puzzle
Pike, L. J. & Forster, S. C., 1 Apr 2018, In : Nature Reviews Microbiology. 16, 4, 1 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Commensal Koch's postulates: establishing causation in human microbiota research
Neville, B. A., Forster, S. C. & Lawley, T. D., 1 Apr 2018, In : Current Opinion in Microbiology. 42, p. 47-52 6 p.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access
File
Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection
Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Culturing of female bladder bacteria reveals an interconnected urogenital microbiota
Thomas-White, K., Forster, S. C., Kumar, N., Van Kuiken, M., Putonti, C., Stares, M. D., Hilt, E. E., Price, T. K., Wolfe, A. J. & Lawley, T. D., 1 Dec 2018, In : Nature Communications. 9, 1, 7 p., 1557.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance
Stringer, J., Forster, S., Qu, Z., Prokopuk, L. A., O'Bryan, M. K., Gardner, D. K., White, S., Adelson, D. L. & Western, P. S., 20 Sep 2018, In : BMC Biology. 16, 20 p., 104.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Activities 2015 2015
- 2 External research organisation, centre or institute
NHMRC CJ Martin Overseas Biomedical Fellowship
Sam Forster (Visitor)1 Jan 2015 → 31 Dec 2018
Activity: External Academic Engagement › External research organisation, centre or institute
NHMRC CJ Martin Overseas Biomedical Fellowship
Sam Forster (Visitor)1 Jan 2015 → 31 Dec 2018
Activity: External Academic Engagement › External research organisation, centre or institute