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Research Output 1997 2019

Absolute quantitation of MDR1 transcripts using heterologous DNA standards - Validation of the competitive RT-PCR (CRT-PCR) approach

El-Osta, A., Kantharidis, P. & Zalcberg, J., 1999, In : BioTechniques. 26, 6, p. 1114-1124 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Age-related differential structural and transcriptomic responses in the hypertensive heart

Marques, F. Z., Chu, P. Y., Ziemann, M., Kaspi, A., Kiriazis, H., Du, X. J., El-Osta, A. & Kaye, D. M., 9 Jul 2018, In : Frontiers in Physiology. 9, JUL, 13 p., 817.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Alleviating transcriptional inhibition of the norepinephrine Slc6a2 transporter gene in depolarized neurons

Harikrishnan, K. N., Bayles, R., Ciccotosto, G. D., Maxwell, S., Cappai, R., Pelka, G. J., Tam, P. P. L., Christodoulou, J. & El-Osta, A., 27 Jan 2010, In : Journal of Neuroscience. 30, 4, p. 1494-1501 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance

Kantharidis, P., El-Osta, A., DeSilva, M., Wall, D. M. P., Hu, X. F., Slater, A., Nadalin, G., Parkin, J. D. & Zalcberg, J. R., Nov 1997, In : Clinical Cancer Research. 3, 11, p. 2025-2032 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Analysis of chromatin-immunopurified MeCP2-associated fragments

El-Osta, A. & Wolffe, A. P., 7 Dec 2001, In : Biochemical and Biophysical Research Communications. 289, 3, p. 733-737 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Analysis of the barley leaf transcriptome under salinity stress using mRNA-Seq

Ziemann, M., Kamboj, A., Hove, R. M., Loveridge, S., El-Osta, A. & Bhave, M., Jun 2013, In : Acta Physiologiae Plantarum. 35, 6, p. 1915-1924 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Analysis of the IGF2/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal growth disorders

Demars, J., Shmela, M. E., Rossignol, S., Okabe, J., Netchine, I., Azzi, S., Cabrol, S., le Caignec, C., David, A., Le Bouc, Y., El-Osta, A. & Gicquel, C., Mar 2010, In : Human Molecular Genetics. 19, 5, p. 803-814 12 p., ddp549.

Research output: Contribution to journalArticleResearchpeer-review

A pipeline for the identification and characterization of chromatin modifications derived from ChIP-Seq datasets

Kaspi, A., Ziemann, M., Rafehi, H., Lazarus, R. & El-Osta, A., 2012, In : Biochimie. 94, 11, p. 2353-2359 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Applicability of histone deacetylase inhibition for the treatment of spinal muscular atrophy

Lunke, S. & El-Osta, A., 2013, In : Neurotherapeutics. 10, 4, p. 677 - 687 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Atherogenic factors and their epigenetic relationships

Fernandez, A. Z., Siebel, A. L. & El-Osta, A., 2010, In : International Journal of Vascular Medicine. 2010, 437809.

Research output: Contribution to journalReview ArticleResearchpeer-review

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

Harikrishnan, K. N., Chow, M. Z., Baker, E. K., Pal, S., Bassal, S., Brasacchio, D., Wang, L., Craig, J. M., Jones, P. L., Sif, S. & El-Osta, A., 2005, In : Nature Genetics. 37, 3, p. 254-264 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cardiac genes show contextual SWI/SNF interactions with distinguishable gene activities

Chang, L., Kiriazis, H., Gao, X. M., Du, X. J. & El-Osta, A., 2011, In : Epigenetics. 6, 6, p. 760-768 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cardiac ventricular chambers are epigenetically distinguishable

Mathiyalagan, P., Chang, L., Du, X. J. & El-Osta, A., 1 Feb 2010, In : Cell Cycle. 9, 3, p. 612-617 6 p.

Research output: Contribution to journalArticleResearchpeer-review

ChIP sequencing

Lunke, S. & El-Osta, A., 2011, Epigenetics: A Reference Manual. Craig, J. M. & Wong, N. C. (eds.). Norfolk UK: Caister Academic Press, p. 357 - 370 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Chromatin context and ncRNA highlight targets of MeCP2 in brain

Maxwell, S. S., Pelka, G. J., Tam, P. P. L. & El-Osta, A., Nov 2013, In : RNA Biology. 10, 11, p. 1741-1757 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromatin modifications and DNA double-strand breaks: The current state of play

Karagiannis, T. C. & El-Osta, A., 1 Jan 2007, In : Leukemia. 21, 2, p. 195-200 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Chromatin modifications and radiotherapy

Mah, L-J., Ververis, K., El-Osta, A. & Karagiannis, T., 2011, Epigenomic Medicine. Karagiannis, T. C. (ed.). Kerala, India: Transworld Research Network, p. 101-124 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Chromatin modifications associated with diabetes

Keating, S. T. & El-Osta, A., 2012, In : Journal of Cardiovascular Translational Research. 5, 4, p. 399-412 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromatin modifications remodel cardiac gene expression

Mathiyalagan, P., Keating, S. T., Du, X-J. & El-Osta, A., 2014, In : Cardiovascular Research. 103, 1, p. 7-16 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromatin modifying agents - The cutting edge of anticancer therapy

Kwa, F. A. A., Balcerczyk, A., Licciardi, P., El-Osta, A. & Karagiannis, T. C., Jul 2011, In : Drug Discovery Today. 16, 13-14, p. 543-547 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Clinical applicability of methylome sequencing in a pilot study of ischemic stroke individuals

Ziemann, M., Kaipananickal, H., Khurana, I., Kaspi, A., Keating, S. T., De Silva, D. A., Moe, K. T. & El-Osta, A., Jan 2015, In : Methods in Next Generation Sequencing. 2, 1, p. 11-22 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer

Karagiannis, T. C. & El-Osta, A., 1 Jan 2006, In : Epigenetics. 1, 3, p. 121-126 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Clonogenic assay: Adherent cells

Rafehi, H., Orlowski, C., Georgiadis, G. T., Ververis, K., El-Osta, A. & Karagiannis, T. C., Mar 2011, In : Journal of Visualized Experiments. 49, 4 p., e2573.

Research output: Contribution to journalArticleOtherpeer-review

Contemporary Trends Emerging in Epigenomics and Metabolism

El-Osta, A., 10 Oct 2018, In : Antioxidants and Redox Signaling. 29, 11, p. 1019-1022 4 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1

Whitham, M., Chan, M. H. S., Pal, M., Matthews, V. B., Prelovsek, O., Lunke, S., El-Osta, A., Broenneke, H., Alber, J., Bruning, J. C., Wunderlich, F. T., Lancaster, G. I. & Febbraio, M. A., 30 Mar 2012, In : Journal of Biological Chemistry. 287, 14, p. 10771-10779 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Coordination of epigenetic events

El-Osta, A., 1 Sep 2004, In : Cellular and Molecular Life Sciences. 61, 17, p. 2135-2136 2 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Current advances in noncoding RNA relevant to epigenetic mechanisms

Mathiyalagan, P., Khan, W., Du, X-J. & El-Osta, A., Mar 2015, In : Current Molecular Biology Reports. 1, 1, p. 29 - 38 10 p.

Research output: Contribution to journalArticleOtherpeer-review

Current Epigenetic Perspective on Diabetes: Who Regulates the Regulators?

Keating, S. T. & El-Osta, A., 18 Dec 2015, In : Cellular & Molecular Medicine: Open access. 1, p. 1-4 4 p., 7.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Current perspectives in Set7 mediated stem cell differentiation

Karimnia, N., Rafehi, H., Tuano, N. K., Ziemann, M., K.N., H., Okabe, J. & El-Osta, A., 4 Dec 2016, In : Non-Coding RNA. 2, 4, 8 p., 2040014.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Deep sequencing reveals increased DNA methylation in chronic rat epilepsy

Kobow, K., Kaspi, A., Harikrishnan, KN., Kiese, K., Ziemann, M., Khurana, I., Fritzsche, I., Hauke, J., Hahnen, E. T., Coras, R., Muhlebner, A., El-Osta, A. & Blumcke, I., 2013, In : Acta Neuropathologica. 126, 5, p. 741-756 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Deep sequencing reveals novel Set7 networks

Keating, S. T., Ziemann, M., Okabe, J., Khan, A. W., Balcerczyk, A. & El-Osta, A., 2014, In : Cellular and Molecular Life Sciences. 71, 22, p. 4471-4486 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages

Escher, G., Hoang, A., Georges, S., Tchoua, U., El-Osta, A., Krozowski, Z. & Sviridov, D., 1 Feb 2005, In : Journal of Lipid Research. 46, 2, p. 356-365 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Developmental origins of disease: Effects of parental diet on asthma

Royce, S. G., Dang, W., Tang, M. L. K., El-Osta, A. & Karagiannis, T. C., 2011, Epigenomic Medicine. Karagiannis, T. C. (ed.). Kerala India: Transworld Research Network, p. 77 - 91 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Development of novel activin-targeted therapeutics

Chen, J., Walton, K., Al-Musawi, S., Kelly, E. M., Qian, H., La, M., Lu, L., Lovrecz, G. O., Ziemann, M., Lazarus, R., El-Osta, A., Gregorevic, P. & Harrison, C. A., 2015, In : Molecular Therapy. 23, 3, p. 434-444 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Diet during Pregnancy is Implicated in the Regulation of Hypothalamic RNA Methylation and Risk of Obesity in Offspring

Kaspi, A., Khurana, I., Ziemann, M., Connor, T., Spolding, B., Zimmet, P., Walder, K. & El-Osta, A., 1 Jul 2018, In : Molecular Nutrition and Food Research. 62, 14, 10 p., 1800134.

Research output: Contribution to journalArticleResearchpeer-review

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments

Karagiannis, T. C., Kn, H. & El-Osta, A., 7 Jun 2007, In : Oncogene. 26, 27, p. 3963-3971 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Distinguishing hyperglycemic changes by set7 in vascular endothelial cells

Okabe, J., Orlowski, C., Balcerczyk, A., Tikellis, C., Thomas, M. C., Cooper, M. E. & El-Osta, A., 2012, In : Circulation Research. 110, 8, p. 1067 - 1076 10 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA damage detection and repair, and the involvement of epigenetic states

Bassal, S. & El-Osta, A., 21 Feb 2005, In : Human Mutation. 25, 2, p. 101-109 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

DNA double-strand breaks repair pathways in the framework of chromatin

Karagiannis, T. C. & El-Osta, A., 1 Dec 2007, New Research on DNA Repair. Nova Science Publishers, p. 295-324 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

DNA methylation and histone deacetylation in the control of gene expression: Basic biochemistry to human development and disease

El-Osta, A. & Wolffe, A. P., 7 Dec 2000, In : Gene Expression. 9, 1-2, p. 63-75 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

DNA methylation regulates hypothalamic gene expression linking parental diet during pregnancy to the offspring's risk of obesity in Psammomys obesus

Khurana, I., Kaspi, A., Ziemann, M., Block, T., Connor, T., Spolding, B., Cooper, A., Zimmet, P., El-Osta, A. & Walder, K., 1 Jul 2016, In : International Journal of Obesity. 40, 7, p. 1079-1088 10 p.

Research output: Contribution to journalArticleResearchpeer-review

DNMT cooperativity - The developing links between methylation, chromatin structure and cancer

El-Osta, A., 1 Nov 2003, In : BioEssays. 25, 11, p. 1071-1084 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Double-strand breaks: Signaling pathways and repair mechanisms

Karagiannis, T. C. & El-Osta, A., 1 Sep 2004, In : Cellular and Molecular Life Sciences. 61, 17, p. 2137-2147 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Double-strand breaks and the concept of short- and long-term epigenetic memory

Orlowski, C., Mah, L-J., Vasireddy, R. S., El-Osta, A. & Karagiannis, T. C., Apr 2011, In : Chromosoma. 120, 2, p. 129-149 21 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain

Gibson, J. H., Slobedman, B., KN, H., Williamson, S. L., Minchenko, D., El-Osta, A., Stern, J. L. & Christodoulou, J., 26 Apr 2010, In : BMC Neuroscience. 11, 53.

Research output: Contribution to journalArticleResearchpeer-review

Dynamic changes in the cardiac methylome during postnatal development

Sim, C. B., Ziemann, M., Kaspi, A., Harikrishnan, K. N., Ooi, J., Khurana, I., Chang, L., Hudson, J. E., El-Osta, A. & Porrello, E. R., 1 Apr 2015, In : FASEB Journal. 29, 4, p. 1329-1343 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host-virus interactions

Perez, S., Gevor, M., Davidovich, A., Kaspi, A., Yamin, K., Domovich, T., Meirson, T., Matityahu, A., Brody, Y., Stemmer, S. M., El-Osta, A., Haviv, I., Onn, I. & Gal-Tanamy, M., 18 Mar 2019, In : Nucleic Acids Research. 47, 5, p. 2455-2471 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Effect of Dietary Fibre Intake and the Gut Microbiota in a Model of Heart Failure

Coelho Marques, F., Nelson, E. M., Chu, P. Y., Horlock, D., Fiedler, A., Ziemann, M. D., Tan, J., Kuruppu, D. M. S., Rajapakse, N., El-Osta, A., Mackay, C. R. & Kaye, D. M., 11 Nov 2016. 1 p.

Research output: Contribution to conferenceAbstractOther