Sam El-Osta

Professor

Professor (Research), Diabetes

Accepting PhD Students

PhD projects

Epigenetics of diabetes, mapping the human methylome and building the epigenomic atlas of Type 1 Diabetes ncRNAs and histone code changes mediate epigenetic events and gene expression in heart disease MeCP2 interacting ncRNAs associated with gene regulatory changes Set7 methyltransferase as a target to reduce the burden of diabetic vascular and renal complications ROS mediated epigenetic changes associated with hyperglycemic memory

Research activity per year

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5 Active
8 Finished

13 results

Active

Cytosine methylation predicts diabetic nephropathy progression
El-Osta, S., Groop, P., Khurana, I. & Maxwell, S. S.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/21 → 31/12/23
Project: Research
Reducing the burden of chronic kidney disease in the indigenous population - the PROPHECY CKD study
Cooper, M., Morey, K., Zimmet, P., Mentha, R., Jandeleit-Dahm, K., El-Osta, S., McDonald, S. P. & Khurana, I.
1/06/20 → 31/05/23
Project: Research
Molecular control of postnatal heart development
Porrello, E. R., El-Osta, S., Delbridge, L. M. & Hudson, J. E.
1/01/19 → 31/12/21
Project: Research
New models of gene regulation in diabetic complications
El-Osta, S. & Khurana, I.
1/01/19 → 31/12/23
Project: Research
Targeting epigenetic pathways that lead to diabetic complications
Cooper, M., El-Osta, S., Jandeleit-Dahm, K., Quaggin, S. & Khurana, I.
1/01/18 → 31/12/21
Project: Research
Finished

Epigenetic programming by histone methyltransferase in the bone marrow hematopoietic stem cells contributes diabetic associated atherosclerosis
Okabe, J., El-Osta, S., Nunes Masi, L., Kaspi, A. D., Murphy, A. J., Cooper, M. & Khurana, I.
1/08/19 → 31/07/20
Project: Research
DESIRE: Epigenome project for DESIRE (Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy.
El-Osta, S., Khurana, I., Kobow, K. & Blümcke, I.
Universitatsklinikum Erlangen of Maxlmilianspl.
4/05/18 → 4/05/19
Project: Research
The Persisting Vascular Effects of Activation of the Renin-Angiotensin System
Thomas, M. & El-Osta, S.
1/01/17 → 31/01/18
Project: Research
Epigenetic determinants of nephropathy in adults with type 1 diabetes
El-Osta, S., Thomas, M., Cooper, M., Groop, P. & Khurana, I.
1/01/17 → 31/12/17
Project: Research
Identifying the epigenomic fingerprint of coronary heart disease in Chinese adults with type 2 diabetes
El-Osta, S., Huang, Y., Chan, J. C. N., Thomas, M., Cooper, M. & Khurana, I.
1/01/16 → 31/12/20
Project: Research
Regulation of heart development and regeneration by DNA methylation
Porrello, E. R. & El-Osta, S.
1/01/15 → 30/06/18
Project: Research
JDRF/NHMRC Diabetes Complications Centre of Research Excellence
Cooper, M., Thomas, M., El-Osta, S., Jandeleit-Dahm, K., Groop, P., Bach, L., Wilkinson-Berka, J. & Khurana, I.
1/12/14 → 30/11/19
Project: Research
Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy.
El-Osta, S. & Khurana, I.
1/01/14 → 30/09/17
Project: Research

Search results