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Personal profile

Biography

El-Osta research group: www.med.monash.edu/cecs/diabetes/research/el-osta-group.html

Professor El-Osta is an epigeneticist and his research is recognized at the highest international level and this is clearly demonstrated by his rapid upward trajectory with respect to publications including citations. He has contributed more than 175 articles and publishes research that is highly influential in the field of transcription and chromatin biology. In recognition of his research into epigenetics, he was awarded AMGEN Australian Medical Researcher of the Year in 2006 by the ASMR Australian Society for Medical Research. The inclusion of his prominent research into the Faculty of 1000 Biology and Nature Milestones as well as most read articles in Circulation Research "honor roll" for 2011 exemplify an authoritative position, influence, and international reputation. While frequently invited to write editorials, his research is recognized in editorials and was awarded in the “2013 Anthology” of most significant science in Circulation Research. He was recently elected vice-president of the International Epigenetics Society and serve as guest editor and solicited to contribute authoritative reviews for prominent journals that in 2015/16 include Antioxidants & Redox Signaling, Cellular and Molecular Life Sciences, Molecular Aspects of Medicine and Circulation Research. As well as his promotion to Professor in 2013 and in recognition of excellence in supervision and mentoring, in 2015, he is a visiting Professor in epigenetics at the Prince of Wales Hospital, Hong Kong as well as an honorary international lecturer with Metropol University (Denmark). His highly original contributions are influential and reflected by prestigious international invitations that include keynote and plenary lectures, which in 2016 include EAS (Austria), EASD (Munich) and IDF-WPR (Taipei). Since 2011, he has received >$6 Million dollars in external research funding, which has become more diversified to include not only NHMRC and Centre of Research Excellence funding but also competitive international sources such as the European Union and FP7 and JDRF. In 2009 he was awarded the prestigious Millennium Type 1 Diabetes Research Award by the Diabetes Australia Research Trust and received the inaugural Juvenile Diabetes Research Foundation & Macquarie Group Foundation in 2009 for diabetes research innovation, in recognition excellence and innovation in medical research. Further evidence of increasing academic achievements by his group includes 7 Ph.D. students graduating and 3 new Ph.D. students with scholarships in the last two years. His reputation for excellence in training, research and technology are considered world class with students obtaining international postdoctoral postings. He is recognized by the NHMRC “honor roll” with prominent international advisory appointments such as ESF, JDRF, and Oxford Global and recently invited to serve on the editorial board for the journals, ncRNA and Epigenetics. As a principal investigator, he leads extensive multidisciplinary collaborative research programs that include leading research sites within the European Union and China.

Biography

INVITATIONS TO CHAIR AND SPEAK INCLUDING REVIEW PANELS (selected)

Professor El-Osta is frequently invited to speak at major international meetings that include keynote and opening lectures and over the past 5 years have presented at local and national meetings on 13 occasions and presented on 63 occasions at international meetings including 12 Plenary/Keynote lectures. International invitations with several keynote and plenary lectures that in 2016 include, Lecture 1st Epigenomics Meeting (Dubrovnik), Plenary lecture 84th European Atherosclerosis Society (Austria), 52nd European Association for the Study of Diabetes (Munich) and Keynote lecture 11th IDF-WPR Congress 2016 & 8th AASD Scientific Meeting (Taipei). Together with Professor Ronald Ma, he is an International Organizer for the Gordon Research Conference, Epigenomics of Diabetes and other Metabolic Diseases, Hong Kong SAR 2018.

                                               

SUPERVISION AND MENTORING

Professor El-Osta has extensive mentoring and supervisory roles for new researchers in the field, with his laboratory hosting international and local scholarship awardees, as well as postdoctoral scientists (HFSP, NHMRC-INSERM, and EFSD). He has a reputation for excellence in training, research and technology continue at the highest international level with postdoctoral postings from Finland, Germany, Italy, Poland, France and The Netherlands. He is a primary and associate supervisor to 33 students (20 Ph.D., 4 MSc, 3 Hons) and 6 completed international trainees. World-class academic achievements in my group are demonstrated and on the rise with six Ph.D. students graduating with doctoral awards and three new Ph.D. students with scholarships in the last two years. He has also helped the career of several early research fellows, many who have now established their own independent research groups achieving funding and fellowships in their own right.

Keywords

  • Diabetes
  • Clinical and Molecular Epigenetics
  • Chromatin
  • DNA and RNA methylation
  • Histones
  • Transcriptional Regulation
  • Computational Epigenomics

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2023

Research Output 1997 2019

Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced Mst1 signaling

Nguyen, M-N., Ziemann, M., Kiriazis, H., Su, Y., Thomas, Z., Lu, Q., Donner, D. G., Zhao, W-B., Rafehi, H., Sadoshima, J., McMullen, J. R., El-Osta, A. & Du, X-J., Jan 2019, In : American Journal of Physiology - Heart and Circulatory Physiology. 316, 1, p. H45-H60 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Age-related differential structural and transcriptomic responses in the hypertensive heart

Marques, F. Z., Chu, P. Y., Ziemann, M., Kaspi, A., Kiriazis, H., Du, X. J., El-Osta, A. & Kaye, D. M., 9 Jul 2018, In : Frontiers in Physiology. 9, JUL, 13 p., 817.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Contemporary Trends Emerging in Epigenomics and Metabolism

El-Osta, A., 10 Oct 2018, In : Antioxidants and Redox Signaling. 29, 11, p. 1019-1022 4 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Diet during Pregnancy is Implicated in the Regulation of Hypothalamic RNA Methylation and Risk of Obesity in Offspring

Kaspi, A., Khurana, I., Ziemann, M., Connor, T., Spolding, B., Zimmet, P., Walder, K. & El-Osta, A., 1 Jul 2018, In : Molecular Nutrition and Food Research. 62, 14, 10 p., 1800134.

Research output: Contribution to journalArticleResearchpeer-review

Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine

Zimmet, P., Shi, Z., El-Osta, A. & Ji, L., 1 Dec 2018, In : Nature Reviews Endocrinology. 14, 12, p. 738-746 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Activities 2008 2019

Clinical Epigenetics (Journal)

Sam El-Osta (Editorial board member)
2019

Activity: Publication peer-review and editorial work typesEditorial responsibility

Cellular and Molecular Life Sciences (Journal)

Sam El-Osta (Editorial board member)
2019

Activity: Publication peer-review and editorial work typesEditorial responsibility

Circulation Research (Journal)

Sam El-Osta (Editorial board member)
20 Jun 2019

Activity: Publication peer-review and editorial work typesEditorial responsibility

Theptarin Diabetes Hospital, Seminar Series

Sam El-Osta (Speaker), Thep Himathongkam (Fellow), Yotsapon Thewjitharoen (Fellow), Rajata Rajatanavim (Fellow), Soontaree Nakasatien (Fellow), Tanya Vannapruegs (Fellow)
22 Jan 2018

Activity: External Academic EngagementExternal research organisation, centre or institute

Department of Foreign Affairs and Trade and Council for Australian-Arab Relations

Sam El-Osta (Keynote/plenary speaker)
5 Dec 2018

Activity: Participating in or organising an event typesContribution to workshop, seminar, course

Press / Media

Fainting Clue Uncovered

Assam El-Osta

18/05/17

1 item of media coverage

Press/Media: Article/Feature