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Personal profile


Saleela works in the Faculty of Medicine, Nursing and Health Sciences at Monash University as a Research Fellow.


  • Lung Cancer
  • Emphysema
  • Il-6
  • Stat3
  • Genetic Models

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Projects 2010 2016

Research Output 2005 2019

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 othersRuwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism

Deswaerte, V., Nguyen, P., West, A., Browning, A. F., Yu, L., Ruwanpura, S. M., Balic, J., Livis, T., Girard, C., Preaudet, A., Oshima, H., Fung, K. Y., Tye, H., Najdovska, M., Ernst, M., Oshima, M., Gabay, C., Putoczki, T. & Jenkins, B. J., 1 Mar 2018, In : Cancer Research. 78, 5, p. 1293-1307 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Lung Diseases

Ruwanpura, S., Rosli, S. & Tate, M., 1 Jan 2018, Inflammasomes: Clinical and Therapeutic Implications. Cordero, M. D. & Alcocer-Gómez, E. (eds.). Cham, Switzerland: Springer, Vol. 108. p. 61-84 24 p. (Experientia Supplementum; vol. 108).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma

Miller, A., McLeod, L., Alhayyani, S., Szczepny, A., Watkins, D. N., Chen, W., Enriori, P., Ferlin, W., Ruwanpura, S. & Jenkins, B. J., 25 May 2017, In : Oncogene. 36, 21, p. 3059-3066 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung

King, P. T., Sharma, R., O'Sullivan, K. M., Callaghan, J., Dousha, L., Thomas, B., Ruwanpura, S., Lim, S., Farmer, M. W., Jennings, B. R., Finsterbusch, M., Brooks, G., Selemidis, S., Anderson, G. P., Holdsworth, S. R. & Bardin, P. G., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 12128.

Research output: Contribution to journalArticleResearchpeer-review

Open Access


Bridging Fellowship

Saleela Ruwanpura (Recipient), 2009

Prize: Prize (including medals and awards)

Cell Biology/Immunology Prize

Saleela Ruwanpura (Recipient), 2011

Prize: Prize (including medals and awards)