If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer

Harrington, B. S., He, Y., Khan, T., Puttick, S., Conroy, P. J., Kryza, T., Cuda, T., Sokolowski, K. A., Tse, B. W. C., Robbins, K. K., Arachchige, B. J., Stehbens, S. J., Pollock, P. M., Reed, S., Weroha, S. J., Haluska, P., Salomon, C., Lourie, R., Perrin, L. C., Law, R. H. P. & 2 others, Whisstock, J. C. & Hooper, J. D., 2020, In : Theranostics. 10, 5, p. 2095-2114 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)
2019

Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library

Li, C. Y., de Veer, S. J., Law, R. H. P., Whisstock, J. C., Craik, D. J. & Swedberg, J. E., 2 Jan 2019, In : ChemBioChem. 20, 1, p. 46-50 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma

Swedberg, J. E., Wu, G., Mahatmanto, T., Durek, T., Caradoc-Davies, T. T., Whisstock, J. C., Law, R. H. P. & Craik, D. J., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 552-560 9 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

Yuan, Y., Ayinuola, Y. A., Singh, D., Ayinuola, O., Mayfield, J. A., Quek, A., Whisstock, J. C., Law, R. H. P., Lee, S. W., Ploplis, V. A. & Castellino, F. J., 1 Oct 2019, In : Journal of Structural Biology. 208, p. 18-29 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding

Quek, A. J. H., Mazzitelli, B. A., Wu, G., Leung, E. W. W., Caradoc-Davies, T. T., Lloyd, G. J., Jeevarajah, D., Conroy, P. J., Sanderson-Smith, M., Yuan, Y., Ayinuola, Y. A., Castellino, F. J., Whisstock, J. C. & Law, R. H. P., 6 Sep 2019, In : Journal of Molecular Biology. 431, 19, p. 3804-3813 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

Pang, S. S., Bayly-Jones, C., Radjainia, M., Spicer, B. A., Law, R. H. P., Hodel, A. W., Parsons, E. S., Ekkel, S. M., Conroy, P. J., Ramm, G., Venugopal, H., Bird, P. I., Hoogenboom, B. W., Voskoboinik, I., Gambin, Y., Sierecki, E., Dunstone, M. A. & Whisstock, J. C., 19 Sep 2019, In : Nature Communications. 10, 1, 9 p., 4288.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Wu, G., Mazzitelli, B. A., Quek, A. J., Veldman, M. J., Conroy, P. J., Caradoc-Davies, T. T., Ooms, L. M., Tuck, K. L., Schoenecker, J. G., Whisstock, J. C. & Law, R. H. P., 12 Mar 2019, In : Blood Advances. 3, 5, p. 729-733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2018

A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent

Sadek, M. M., Barlow, N., Leung, E. W. W., Williams-Noonan, B. J., Yap, B. K., Shariff, F. M., Caradoc-Davies, T. T., Nicholson, S. E., Chalmers, D. K., Thompson, P. E., Law, R. H. P. & Norton, R. S., 19 Oct 2018, In : ACS Chemical Biology. 13, 10, p. 2930-2938 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

Voon, H. P. J., Udugama, M., Lin, W., Hii, L., Law, R. H. P., Steer, D. L., Das, P. P., Mann, J. R. & Wong, L. H., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 3142.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin

Brennan, A. J., Law, R. H. P., Conroy, P. J., Noori, T., Lukoyanova, N., Saibil, H., Yagita, H., Ciccone, A., Verschoor, S., Whisstock, J. C., Trapani, J. A. & Voskoboinik, I., 7 Feb 2018, In : Cell Death and Differentiation. 25, p. 1517-1529 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The first transmembrane region of complement component-9 acts as a brake on its self-assembly

Spicer, B. A., Law, R. H. P., Caradoc-Davies, T. T., Ekkel, S. M., Bayly-Jones, C., Pang, S-S., Conroy, P. J., Ramm, G., Radjainia, M., Venugopal, H., Whisstock, J. C. & Dunstone, M. A., 15 Aug 2018, In : Nature Communications. 9, 1, 7 p., 3266.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
11 Citations (Scopus)
2017

Antibodies: From novel repertoires to defining and refining the structure of biologically important targets

Conroy, P. J., Law, R. H. P., Caradoc-Davies, T. T. & Whisstock, J. C., 1 Mar 2017, In : Methods. 116, p. 12-22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Regulation of perforin activation and pre-synaptic toxicity through C-terminal glycosylation

House, I. G., House, C. M., Brennan, A. J., Gilan, O., Dawson, M. A., Whisstock, J. C., Law, R. H. P., Trapani, J. A. & Voskoboinik, I., 1 Oct 2017, In : EMBO Reports. 18, 10, p. 1775-1785 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors

Law, R. H. P., Wu, G., Leung, E. W. W., Hidaka, K., Quek, A. J., Caradoc-Davies, T. T., Jeevarajah, D., Conroy, P. J., Kirby, N. M., Norton, R. S., Tsuda, Y. & Whisstock, J. C., 9 May 2017, In : Blood Advances. 1, 12, p. 766-771 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)
2016

Molecular pathogenesis of plasminogen Hakodate: the second Japanese family case of severe type I plasminogen deficiency manifested late-onset multi-organic chronic pseudomembranous mucositis

Osaki, T., Souri, M., Song, Y. S., Izumi, N., Law, R. & Ichinose, A., 1 Aug 2016, In : Journal of Thrombosis and Thrombolysis. 42, 2, p. 218-224 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure of the poly-C9 component of the complement membrane attack complex

Dudkina, N. V., Spicer, B. A., Reboul, C. F., Conroy, P. J., Lukoyanova, N., Elmlund, H., Law, R. HP., Ekkel, S. M., Kondos, S. C., Goode, R. J. A., Ramm, G., Whisstock, J. C., Saibil, H. R. & Dunstone, M. A., 4 Feb 2016, In : Nature Communications. 7, 6 p., 10588.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
50 Citations (Scopus)
2015

Conformational changes during pore formation by the perforin-related protein pleurotolysin

Lukoyanova, N., Kondos, S. C., Farabella, I., Law, R. H. P., Reboul, C. F., Caradoc-Davies, T. T., Spicer, B., Kleifeld, O., Traore, D. A. K., Ekkel, S. M., Voskoboinik, I., Trapani, J. A., Hatfaludi, T. Z., Oliver, K., Hotze, E. M., Tweten, R. K., Whisstock, J. C., Topf, M., Saibil, H. R. & Dunstone, M. A., 2015, In : PLoS Biology. 13, 2, 15 p., e1002049.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
55 Citations (Scopus)

Preferential acquisition and activation of plasminogen glycoform II by PAM positive group A streptococcal isolates

De Oliveira, D. M. P., Law, R. H. P., Ly, D., Cook, S. M., Quek, A. J., McArthur, J. D., Whisstock, J. C. & Sanderson-Smith, M. L., 2015, In : Biochemistry. 54, 25, p. 3960 - 3968 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase

Cork, A. J., Ericsson, D. J., Law, R. H. P., Casey, L. W., Valkov, E., Bertozzi, C., Stamp, A., Jovcevski, B., Aquilina, J. A., Whisstock, J. C., Walker, M. J. & Kobe, B., 2015, In : PLoS ONE. 10, 3, 18 p., e0121764.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes

Yagi, H., Conroy, P. J., Leung, E. W. W., Law, R. H. P., Trapani, J. A., Voskoboinik, I., Whisstock, J. & Norton, R. S., 2015, In : Journal of Biological Chemistry. 290, 42, p. 25213-25226 14 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2014

Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain

Bhattacharya, S., Liang, Z., Quek, A. J., Ploplis, V., Law, R. H. P. & Castellino, F. J., 2014, In : Journal of Biological Chemistry. 289, 31, p. 21684 - 21693 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster

Ellisdon, A. M., Zhang, Q., Bennett, M. A., Johnson, T. K., Warr, C. G., Law, R. H. P. & Whisstock, J. C., 2014, In : BMC Structural Biology. 14, 1, p. 1 - 8 8 p., 14.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Maspin is not required for embryonic development or tumour suppression

Teoh, S. S. Y., Vieusseux, J. L., Prakash, M. D., Berkowicz, S. R., Luu, J., Bird, C. H., Law, R. H. P., Rosado, C. J., Price, J. T., Whisstock, J. C. & Bird, P. I., 2014, In : Nature Communications. 5, (Art. No.: 3164), p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
24 Citations (Scopus)

Reconciling the structural attributes of avian antibodies

Conroy, P., Law, R. H. P., Gilgunn, S., Hearty, S., Caradoc-Davies, T. T., Lloyd, G., O'Kennedy, R. & Whisstock, J., 2014, In : Journal of Biological Chemistry. 289, 22, p. 15384 - 15392 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)
2013

Defining the interaction of perforin with calcium and the phospholipid membrane

Traore, D. A. K., Brennan, A. J., Law, R. H. P., Dogovski, C., Perugini, M. A., Lukoyanova, N., Leung, E. W. W., Norton, R. S., Lopez, J., Browne, K. A., Yagita, H., Lloyd, G., Ciccone, A., Verschoor, S., Trapani, J. A., Whisstock, J. & Voskoboinik, I., 2013, In : Biochemical Journal. 456, 3, p. 323 - 335 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

New insights into the structure and function of the plasminogen/plasmin system

Law, R. H. P., Abu-ssaydeh, D. & Whisstock, J., 2013, In : Current Opinion in Structural Biology. 23, 6, p. 836 - 841 6 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

Lopez, J., Susanto, O., Jenkins, M., Lukoyanova, N., Sutton, V. R., Law, R. H. P., Johnston, A., Bird, C. H., Bird, P. I., Whisstock, J., Trapani, J. A., Saibil, H. & Voskoboinik, I., 2013, In : Blood. 121, 14, p. 2659 - 2668 10 p.

Research output: Contribution to journalArticleResearchpeer-review

96 Citations (Scopus)

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

Langendorf, C. G., Tuck, K. L., Key, T., Fenalti, G., Pike, R. N., Rosado, C. J., Wong, A. SM., Buckle, A. M., Law, R. H. P. & Whisstock, J., 2013, In : Bioscience Reports. 33, 1 (Art # A13), p. 137 - 149 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
2012

The extracellular protein factor Epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an n-terminal domain containing a carbohydrate-binding module

Linke, C., Siemens, N., Oehmcke, S., Radjainia, M., Law, R. HP., Whisstock, J. C., Baker, E. N. & Kreikemeyer, B., 2012, In : Journal of Biological Chemistry. 287, 45, p. 38178 - 38189 12 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

The x-ray crystal structure of full-length human plasminogen

Law, R. HP., Caradoc-Davies, T. T., Cowieson, N. P., Horvath, A. J., Quek, A. J., Amarante Da Encarnacao, J., Steer, D. L., Cowan, A. D., Zhang, Q., Lu, B. GC., Pike, R. N., Smith, A. I., Coughlin, P. B. & Whisstock, J. C., 2012, In : Cell Reports. 1, 3, p. 185 - 190 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
109 Citations (Scopus)

X-ray crystal structure of the streptococcal specific phage lysin PlyC

McGowan, S., Buckle, A. M., Mitchell, M. S., Hoopes, J. T., Gallagher, D. T., Heselpoth, R. D., Shen, Y., Reboul, C. F., Law, R. HP., Fischetti, V. A., Whisstock, J. C. & Nelson, D. C., 2012, In : Proceedings of the National Academy of Sciences. 109, 31, p. 12752 - 12757 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
52 Citations (Scopus)
2011

Contribution of conserved lysine residues in the alpha{2}-antiplasmin C terminus to plasmin binding and inhibition

Lu, B. G. C., Sofian, T., Law, R. HP., Coughlin, P. B. & Horvath, A. J., 2011, In : Journal of Biological Chemistry. 286, 28, p. 24544 - 24552 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)
2010

Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery

Nogues, C., Leh, H., Langendorf, C. G., Law, R. H. P., Buckle, A. M. & Buckle, M., 2010, In : PLoS ONE. 5, 8 (e12152), p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

The structural basis for membrane binding and pore formation by lymphocyte perforin

Law, R. H. P., Lukoyanova, N., Voskoboinik, I., Caradoc-Davies, T. T., Baran, K., Dunstone, M. A., D'Angelo, M., Orlova, E. V., Coulibaly, F. J., Verschoor, S., Browne, K. A., Ciccone, A., Kuiper, M. J., Bird, P. I., Trapani, J. A., Saibil, H. R. & Whisstock, J. C., 2010, In : Nature. 468, 7322, p. 447 - 451 5 p.

Research output: Contribution to journalArticleResearchpeer-review

229 Citations (Scopus)

The structure and function of mammalian membrane-attack complex/perforin-like proteins

Kondos, S., Hatfaludi, T. Z., Voskoboinik, I., Trapani, J. A., Law, R. HP., Whisstock, J. C. & Dunstone, M. A., 2010, In : Tissue Antigens. 76, 5, p. 341 - 351 11 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates

Kennan, R. M., Wong, W., Dhungyel, O., Han, X., Wong, D. M., Parker, D., Rosado, C. J., Law, R. HP., McGowan, S., Reeve, S. B., Levina, V., Powers, G. A., Pike, R. N., Bottomley, S. P., Smith, A. I., Marsh, I., Whittington, R. J., Whisstock, J., Porter, C. J. & Rood, J. I., 2010, In : PLoS Pathogens. 6, 11, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions

Langendorf, C., Key, T., Fenalti, G., Kan, W-T., Buckle, A. M., Caradoc-Davies, T. T., Tuck, K. L., Law, R. H. P. & Whisstock, J., 2010, In : PLoS ONE. 5, 2, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2009

A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites

Beckham, S. A., Piedrafita, D. M., Phillips, C. I., Samarawickrema, N., Law, R. H. P., Smooker, P. M., Quinsey, N. S., Irving, J. A., Greenwood, D. L., Verhelst, S. H. L., Bogyo, M., Turk, B., Coetzer, T. H., Wijeyewickrema, L. C., Spithill, T. W. & Pike, R. N., 2009, In : International Journal of Biochemistry and Cell Biology. 41, 7, p. 1601 - 1612 12 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Development and application of a fecal antigen diagnostic sandwich ELISA for estimating prevalence of fasciola gigantica in cattle in central java, Indonesia

Estuningsih, E., Spithill, T. W., Raadsma, H., Law, R. H. P., Adiwinata, G., Meeusen, E. N. T. & Piedrafita, D. M., 2009, In : Journal of Parasitology. 95, p. 450 - 455 6 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Prodepth: Predict residue depth by support vector regression approach from protein sequences only

Song, J., Tan, H., Mahmood, K., Law, R. H. P., Buckle, A. M., Webb, G., Akutsu, T. & Whisstock, J., 2009, In : PLoS ONE. 4, 9 (e7072), p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Structural mechanisms of inactivation in scabies mite serine protease paralogues

Fischer, K., Langendorf, C., Irving, J. A., Reynolds, S., Willis, C., Beckham, S. A., Law, R. H. P., Yang, S., Bashtannyk-Puhalovich, T. A., McGowan, S., Whisstock, J., Pike, R. N., Kemp, D. J. & Buckle, A. M., 2009, In : Journal of Molecular Biology. 390, 4, p. 635 - 645 11 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

Kaiserman, D., Buckle, A. M., Van Damme, P., Irving, J. A., Law, R. H. P., Matthews, A. Y., Bashtannyk-Puhalovich, T. A., Langendorf, C., Thompson, P., Vandekerckhove, J., Gevaert, K., Whisstock, J. C. & Bird, P. I., 2009, In : Proceedings of the National Academy of Sciences. 106, 14, p. 5587 - 5592 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)
2008

A structural basis for Loop C-sheet polymerization in serpins

Zhang, Q., Law, R. H. P., Bottomley, S. P., Whisstock, J. & Buckle, A. M., 2008, In : Journal of Molecular Biology. 376, 5, p. 1348 - 1359 12 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity

Fenalti, G., Hampe, C. S., Arafat, Y., Law, R. H. P., Banga, J. P., Mackay, I. R., Whisstock, J., Buckle, A. M. & Rowley, M. J., 2008, In : Diabetes. 57, 5, p. 1293 - 1301 9 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

The MACPF/CDC family of pore-forming toxins

Rosado, C. J., Kondos, S., Bull, T. E., Kuiper, M., Law, R. H. P., Buckle, A. M., Voskoboinik, I., Bird, P. I., Trapani, J. A., Whisstock, J. & Dunstone, M. A., 2008, In : Cellular Microbiology. 10, 9, p. 1765 - 1774 10 p.

Research output: Contribution to journalArticleResearchpeer-review

175 Citations (Scopus)

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin

Law, R. H. P., Sofian, T., Kan, W-T., Horvath, A. J., Hitchen, C. R., Langendorf, C., Buckle, A. M., Whisstock, J. & Coughlin, P. B., 2008, In : Blood. 111, p. 2049 - 2052 3 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)
2007

A common fold mediates vertebrate defense and bacterial attack

Rosado, C. J., Buckle, A. M., Law, R. H. P., Butcher, R. E., Kan, W-T., Bird, C. H., Ung, K. S., Browne, K. A., Baran, K., Bashtannyk-Puhalovich, T. A., Faux, N. G., Wong, W., Porter, C. J., Pike, R. N., Ellisdon, A. M., Pearce, M. C., Bottomley, S. P., Emsley, J., Smith, A. I., Rossjohn, J. & 6 others, Hartland, E. L., Voskoboinik, I., Trapani, J. A., Bird, P. I., Dunstone, M. A. & Whisstock, J., 2007, In : Science. 317, 5844, p. 1548 - 1551 4 p.

Research output: Contribution to journalArticleResearchpeer-review

190 Citations (Scopus)

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

Fenalti, G., Law, R. H. P., Buckle, A. M., Langendorf, C., Tuck, K. L., Rosado, C. J., Faux, N. G., Mahmood, K., Hampe, C. S., Banga, J. P., Wilce, M. C. J., Schmidberger, J., Rossjohn, J., El-Kabbani, O., Pike, R. N., Smith, A. I., Mackay, I. R., Rowley, M. J. & Whisstock, J., 2007, In : Nature Structural and Molecular Biology. 14, 4, p. 280 - 286 7 p.

Research output: Contribution to journalArticleResearchpeer-review

137 Citations (Scopus)

The N terminus of the serpin, tengpin, functions to trap the metastable native state

Zhang, Q., Buckle, A. M., Law, R. H. P., Pearce, M. C., Cabrita, L., Lloyd, G., Irving, J. A., Smith, A. I., Ruzyla, K., Rossjohn, J., Bottomley, S. P. & Whisstock, J., 2007, In : EMBO Reports. 8, 7, p. 658 - 663 6 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)
2006

An overview of the serpin superfamily

Law, R. H. P., Zhang, Q., McGowan, S., Buckle, A. M., Silverman, G. A., Wong, W., Rosado, C. J., Langendorf, C., Pike, R. N., Bird, P. I. & Whisstock, J., 2006, In : Genome Biology. 7, 5, p. 216-1 - 216-11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

345 Citations (Scopus)