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Personal profile

Biography

Ross is a laboratory head at the Australian Centre for Blood Diseases, a Monash University department at the Alfred Hospital. As a postdoctoral scientist in New York he helped develop RNA interference technology allowing reversible inhibition of endogenous gene expression in cultured cells and in mice. His laboratory now uses these tools to investigate hematopoiesis and leukemia, focusing on genes recurrently mutated in acute myeloid leukemia (AML). Of particular interest is understanding how mutations affecting transcription factors impose the maturation block in acute leukemia, and novel approaches to trigger leukemia differentiation and prevent relapse. His lab also studies how myeloid lineage antigen-presenting cells regulate T cell costimulation in autoimmunity and cancer.

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • Acute myeloid leukaemia
  • Acute lymphoblastic leukaemia
  • Tumour suppressor genes
  • Transcription factors
  • Differentiation therapy

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