Projects per year
Personal profile
Biography
I received my PhD in the fields of Biochemistry and Exosomes Research in 2017 under the supervision of Prof Richard Simpson and A/Prof David Greening. I worked over 3 years as a Research Fellow on extracellular vesicles (Exosomes) in Prof Richard Simpson laboratory at La Trobe University (LTU) (10.2016-06.2020). Currently I work in Prof Christoph Hagemeyer’s laboratory at Monash University as an NHMRC Ideas Grant supported Research Fellow (LV B) on nanoparticle based Smart Glucose Responsive Insulin Release System.
I am recently supported by a Juvenile Diabetes Research Foundation (JDRF), Australian Type 1 Diabetes Clinical Research Network -Early and Mid-Career Basic Researcher Fellowship (AUT1DCRN-EMCRF, 2024-2026). I was awarded with a highly competitive Monash Future Leader Fellowship (MFLF, 2022) to support my exosomes therapy research in cardiovascular diseases prevention. In 2023, I will be supported to lead smart exosomes for the treatment of stroke by two prestigious grants, CASS foundation Medicine/Science grant and Bethlehem Griffiths Research Foundation (BGRF) grant.
Research interests
- Smart injury-responsive and targeted exosomes therapy for preventing cardiovascular diseases, including acute myocardial infarct (AMI), and Stroke.
- Smart glucose-responsive insulin nanoparticles for type diabetes therapy
- Phage library for novel targeting antibodies for various diseases
- Imaging techniques to better understand the underlying mechanisms of different diseases progression and the impact of therapy of targeted nanoparticle and exosomes (ultrasound and photoacoustic Vevo F2, PET, MRI, MPI, CT).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Engineering targeted thrombolytic and brain-rejuvenating nano-carriers for the treatment of acute ischemic stroke
Xu, R. (Primary Chief Investigator (PCI)), Hagemeyer, C. (Chief Investigator (CI)) & Niego, B. (Chief Investigator (CI))
1/01/23 → 31/07/27
Project: Research
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LTU Strategic Innovation Fund
Xu, R. (Chief Investigator (CI)), Greening, D. W. (Chief Investigator (CI)) & Simpson, R. J. (Primary Chief Investigator (PCI))
1/04/19 → 31/12/20
Project: Research
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Clinical relevance of extracellular vesicles in cancer — therapeutic and diagnostic potential
Greening, D. (Leading Author), Xu, R. (Leading Author), Rai, A., Suwakulsiri, W., Chen, M. & Simpson, R. J. (Leading Author), Dec 2025, In: Nature Reviews Clinical Oncology. 22, 12, p. 924–952 29 p.Research output: Contribution to journal › Review Article › Research › peer-review
7 Citations (Scopus) -
Collagen-targeted tracers for molecular imaging of atrial fibrosis and sensitive detection of atrial fibrillation
Niego, B. (Leading Author), Hagemeyer, C. (Leading Author), Jupp, B., Noor, A., Donnelly, P., Xu, R., Mendis, T., Chen, Y. C., Carmichael, I., McMullen, J. (Leading Author) & Alt, K. (Leading Author), 6 Oct 2025, In: npj Cardiovascular Health. 2, 13 p., 49.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Nanotherapeutics in Kidney Disease
Roointan, A., Xu, R., Corrie, S., Hagemeyer, C. E. & Alt, K., Mar 2025, In: Journal of the American Society of Nephrology. 36, 3, p. 500-518 19 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access10 Citations (Scopus) -
Thrombolytic drugs for ischemic stroke: Historical perspective, State of play and future developments
Walie, B. E. (Leading Author), Hagemeyer, C., Xu, R. & Niego, B. (Leading Author), Oct 2025, (Accepted/In press) In: Journal of Thrombosis and Thrombolysis. 38 p., JTHA-D-25-00498R1.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
Comparative proteomic analysis of three major extracellular vesicle classes secreted from human primary and metastatic colorectal cancer cells: Exosomes, microparticles, and shed midbody remnants
Suwakulsiri, W., Xu, R., Rai, A., Shafiq, A., Chen, M., Greening, D. W. & Simpson, R. J., Jun 2024, In: Proteomics. 24, 11, 23 p., 2300057.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus)
Prizes
Activities
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Research in Progress Meeting
Xu, R. (Invited speaker)
2023Activity: Participating in or organising an event types › Contribution to conference
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Frontiers in Oncology (Journal)
Xu, R. (Associate editor)
2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Research Symposium for Chinese PhD Students and Scholars in Australia
Xu, R. (Session chair)
2022Activity: Participating in or organising an event types › Contribution to conference
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Pharmaceutics (Journal)
Xu, R. (Guest editor)
2021 → 2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Frontiers in Cellular Neuroscience (Journal)
Xu, R. (Guest editor)
2021 → 2022Activity: Publication peer-review and editorial work types › Editorial responsibility