Romana Stark

Dr

Accepting PhD Students

20072023
If you made any changes in Pure these will be visible here soon.

Research Output 2007 2019

2019

Glucose availability regulates ghrelin-induced food intake in the ventral tegmental area

Lockie, S. H., Stark, R., Spanswick, D. C. & Andrews, Z. B., 11 Feb 2019, (Accepted/In press) In : Journal of Neuroendocrinology. 6 p., e12696.

Research output: Contribution to journalArticleResearchpeer-review

2018

AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning

Reichenbach, A., Stark, R., Mequinion, M., Denis, R. R. G., Goularte, J. F., Clarke, R. E., Lockie, S. H., Lemus, M. B., Kowalski, G. M., Bruce, C. R., Huang, C., Schittenhelm, R. B., Mynatt, R. L., Oldfield, B. J., Watt, M. J., Luquet, S. & Andrews, Z. B., 13 Feb 2018, In : Cell Reports. 22, 7, p. 1745-1759 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction

Reichenbach, A., Stark, R., Mequinion, M., Lockie, S. H., Lemus, M. B., Mynatt, R. L., Luquet, S. & Andrews, Z. B., 1 Dec 2018, In : FASEB Journal. 32, 12, p. 6923-6933 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice

Reichenbach, A., Mequinion, M., Bayliss, J. A., Lockie, S. H., Lemus, M. B., Mynatt, R. L., Stark, R. & Andrews, Z. B., 1 Jun 2018, In : Endocrinology. 159, 6, p. 2473-2483 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons

Lockie, S. H., Stark, R., Mequinion, M., Ch'ng, S., Kong, D., Spanswick, D. C., Lawrence, A. J. & Andrews, Z. B., 1 Nov 2018, In : Endocrinology. 159, 11, p. 3605-3614 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid β (Aβ1-40) administration in mice

Santos, V. V., Stark, R., Rial, D., Silva, H. B., Bayliss, J. A., Lemus, M. B., Davies, J. S., Cunha, R. A., Prediger, R. D. S. & Andrews, Z. B., 1 May 2017, In : Journal of Neuroendocrinology. 29, 5, 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Transient receptor potential canonical 3 (TRPC3) channels are required for hypothalamic glucose detection and energy homeostasis

Chretien, C., Fenech, C., Lienard, F., Grall, S., Chevalier, C., Chaudy, S., Brenachot, X., Berges, R., Louche, K., Stark, R., Nedelec, E., Laderriere, A., Andrews, Z. B., Benani, A., Flockerzi, V., Gascuel, J., Hartmann, J., Moro, C., Birnbaumer, L., Leloup, C. & 2 othersPenicaud, L. & Fioramonti, X., Feb 2017, In : Diabetes. 66, 2, p. 314-324 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Des-acyl ghrelin and ghrelin O-acyltransferase regulate hypothalamic-pituitary-adrenal axis activation and anxiety in response to acute stress

Stark, R., Santos, V. V., Geenen, B., Cabral, A., Dinan, T., Bayliss, J. A., Lockie, S. H., Reichenbach, A., Lemus, M. B., Perello, M., Spencer, S. J., Kozicz, T. & Andrews, Z. B., Oct 2016, In : Endocrinology. 157, 10, p. 3946-3957 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Ghrelin-AMPK signaling mediates the neuroprotective effects of calorie restriction in Parkinson's Disease

Bayliss, J. A., Lemus, M. B., Stark, R., Santos, V. V., Thompson, A., Rees, D. J., Galic, S., Elsworth, J. D., Kemp, B. E., Davies, J. S. & Andrews, Z. B., 9 Mar 2016, In : Journal of Neuroscience. 36, 10, p. 3049-3063 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Acyl ghrelin acts in the brain to control liver function and peripheral glucose homeostasis in male mice

Stark, R., Reichenbach, A., Lockie, S. K. H., Pracht, C., Wu, Q., Tups, A. & Andrews, Z. B., 2015, In : Endocrinology. 156, 3, p. 858 - 868 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A stereological analysis of NPY, POMC, Orexin, GFAP astrocyte, and Iba1 microglia cell A stereological analysis of NPY, POMC, Orexin, GFAP astrocyte, and Iba1 microglia cell number and volume in diet-induced obese male mice

Lemus, M. B., Bayliss, J. A., Lockie, S. K. H., Santos, V. V., Reichenbach, A., Stark, R. & Andrews, Z. B., 2015, In : Endocrinology. 156, 5, p. 1701 - 1713 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypothalamic carnitine metabolism integrates nutrient and hormonal feedback to regulate energy homeostasis

Stark, R., Reichenbach, A. & Andrews, Z. B., 2015, In : Molecular and Cellular Endocrinology. 418, p. 9 - 16 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A role for mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) in the regulation of hepatic gluconeogenesis

Stark, R., Guebre-Egziabher, F., Zhao, X., Feriod, C., Dong, J., Alves, T. C., Ioja, S., Pongratz, R. L., Bhanot, S., Roden, M., Cline, G., Shulman, G. I. & Kibbey, R. G., 4 Feb 2014, In : Journal of Biological Chemistry. 289, 11, p. 7257-7263 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice

Briggs, D. I., Lockie, S. K. H., Benzler, J., Wu, Q., Stark, R., Reichenbach, A., Hoy, A. J., Lemus, M. B., Coleman, H. A., Parkington, H. C., Tups, A. & Andrews, Z. B., 2014, In : Endocrinology. 155, 7, p. 2411 - 2422 12 p.

Research output: Contribution to journalArticleResearchpeer-review

NPY neurons as a critical hypothalamic node for the control of GH release relative to food intake

Huang, L., Sukor, N. (ed.), Tan, H. Y., Fogarty, M. J., Stark, R., Andrews, Z. B., Veldhuis, J. D., Herzog, H., Chen, C. & Steyn, F. J., 2014, p. 11 - 11. 1 p.

Research output: Contribution to conferenceAbstractOther

The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?

Stark, R. & Kibbey, R. G., 2014, In : Biochimica et Biophysica Acta. General Subjects. 1840, 4, p. 1313 - 1330 18 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of the Ghrelin Receptor in appetite and energy metabolism

Andrews, Z. B. & Stark, R., 1 Jan 2014, Central Functions of the Ghrelin Receptor. Portelli, J. & Smolders, I. (eds.). 1st ed. USA: Humana Press, p. 35-52 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The temporal pattern of cfos activation in hypothalamic, cortical, and brainstem nuclei in response to fasting and refeeding in male mice

Wu, Q., Lemus, M. B., Stark, R., Bayliss, J., Reichenbach, A., Lockie, S. K. H. & Andrews, Z. B., 2014, In : Endocrinology. 155, 3, p. 840 - 853 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

AMPK and the neuroendocrine regulation of appetite and energy expenditure

Stark, R., Ashley, S. E. & Andrews, Z. B., 2013, In : Molecular and Cellular Endocrinology. 366, 2, p. 215 - 223 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Calorie-restricted weight loss reverses high-fat diet-induced ghrelin resistance, which contributes to rebound weight gain in a ghrelin-dependent manner

Briggs, D. I., Lockie, S. K. H., Wu, Q., Lemus, M. B., Stark, R. & Andrews, Z. B., 2013, In : Endocrinology. 154, 2, p. 709 - 717 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance

Boon, J. Y. C., Hoy, A. J., Stark, R., Brown, R. D., Meex, R. CR., Henstridge, D. C., Schenk, S., Meikle, P. J., Horowitz, J. F., Kingwell, B. A., Bruce, C. & Watt, M. J., 2013, In : Diabetes. 62, 2, p. 401 - 410 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypothalamic Control of Appetite and Energy Metabolism

Reichenbach, A., Stark, R. & Andrews, Z. B., 2013, The Human Hypothalamus: Anatomy, Functions and Disorders. Dudas, B. (ed.). 1st ed. New York: Nova Science Publishers, p. 247 - 281 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2012

Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase

Pagnon, J., Matzaris, M., Stark, R., Meex, R. CR., Macaulay, S. L., O'Brien, P. E., Tiganis, T., Watt, M. J. & Brown, W. A., 2012, In : Endocrinology. 153, 9, p. 4278 - 4289 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Gut Hormones restrict neurodegeneration in Parkinson's Disease

Bayliss, J., Stark, R., Reichenbach, A. & Andrews, Z. B., 2011, Advanced Understanding of Neurodegenerative Diseases. Chang, R. C-C. (ed.). 1st ed. Croatia: In-Tech, p. 269 - 284 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats

Jamison, R. A., Stark, R., Dong, J., Yonemitsu, S., Zhang, D., Shulman, G. I. & Kibbey, R. G., 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 6, p. 1174 - 1183 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation in a rat model of insulin resistance

Weismann, D., Erion, D. M., Ignatova-Todorova, I., Nagai, Y., Stark, R., Hsiao, J. J., Flannery, C. A., Birkenfeld, A. L., May, T., Khan, M., Zhang, D., Yu, X., Murray, S. F., Bhanot, S., Monia, B. P., Cline, G., Shulman, G. I. & Samuel, V. T., 2011, In : Diabetologia. 54, 4, p. 935 - 944 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion

Stark, R., Pasquel, F., Turcu, A., Pongratz, R., Roden, M., Cline, G., Shulman, G. I. & Kibbey, R. G., 2009, In : Journal of Biological Chemistry. 284, 39, p. 26578 - 26590 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Prevention of Hepatic Steatosis and Hepatic Insulin Resistance by Knockdown of cAMP Response Element-Binding Protein

Erion, D. M., Ignatova-Todorova, I., Yonemitsu, S., Nagai, Y., Chatterjee, P., Weismann, D., Hsiao, J. J., Zhang, D., Iwasaki, T., Stark, R., Flannery, C. A., Khan, M., Carmean, C. M., Yu, X., Murray, S. F., Bhanot, S., Monia, B. P., Cline, G., Samuel, V. T. & Shulman, G. I., 2009, In : Cell Metabolism. 10, 6, p. 499 - 506 8 p.

Research output: Contribution to journalArticleResearchpeer-review

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

Erion, D. M., Yonemitsu, S., Nie, Y., Nagai, Y., Gillum, M. P., Hsiao, J. J., Iwasaki, T., Stark, R., Weismann, D., Yu, X., Murray, S. F., Bhanot, S., Monia, B. P., Horvath, T. L., Gao, Q., Samuel, V. T. & Shulman, G. I., 2009, In : Proceedings of the National Academy of Sciences. 106, 27, p. 11288 - 11293 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The Role of Peroxisome Proliferator-Activated Receptor ? Coactivator-1 ? in the Pathogenesis of Fructose-Induced Insulin Resistance

Nagai, Y., Yonemitsu, S., Erion, D. M., Iwasaki, T., Stark, R., Weismann, D., Dong, J., Zhang, D., Jurczak, M. J., Loffler, M. G., Cresswell, J., Yu, X., Murray, S. F., Bhanot, S., Monia, B. P., Bogan, J. S., Samuel, V. T. & Shulman, G. I., 2009, In : Cell Metabolism. 9, 3, p. 252 - 264 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Mitochondrial function and endocrine diseases

Stark, R. & Roden, M., 2007, In : European Journal of Clinical Investigation. 37, 4, p. 236 - 248 13 p.

Research output: Contribution to journalArticleResearchpeer-review