Projects per year
Personal profile
Biography
Professor Roger Daly relocated his laboratory to Monash University in March 2013, where he is currently Head of the Department of Biochemistry and Molecular Biology and Head of the Biomedicine Discovery Institute Cancer Program. Professor Daly is an internationally recognised expert in growth factor receptor signaling and its deregulation in cancer. Over the last 10 years he has established cutting-edge technology platforms in mass spectrometry-based proteomics and kinomics. These have been successfully applied to the characterisation of cancer signaling networks with the goal of identifing novel therapeutic targets and biomarkers.
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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Cancer
- Cancer Cell Biology
- Signal Transduction
- Signalling pathways
- Mass Spectrometry
Collaborations and top research areas from the last five years
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A novel oncogenic alliance in breast cancer
Daly, R., Ooms, L. & O'Toole, S. A.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/17 → 31/12/19
Project: Research
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Identification of novel therapeutic targets for triple negative breast cancer through integrative kinomics
Daly, R., Ganju, V., Loi, S., Mitchell, C. & Simpson, K. J.
1/06/15 → 31/05/16
Project: Research
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A novel, therapeutically actionable, signalling axis in poor prognosis cancers
Daly, R., Ellisdon, A., Lucet, I., Stratton, M., Tiganis, T., Pajic, M., Abud, H., Shackleton, M., Jarde, T. & Swarbrick, A.
1/01/25 → 31/12/28
Project: Research
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Studying communication between cancer-associated fibroblasts and breast cancer cells to identify druggable vulnerabilities
Jarde, T., Richardson, G. E., Daly, R., Merino, D., Leung, D., Fennell, L., Abud, H., Ingham, S. & Port, M.
6/04/24 → 5/04/27
Project: Research
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COX2-driven T cell suppression in the colorectal cancer microenvironment
Fletcher, A., Wilkins, S., McMurrick, P., Abud, H., Daly, R., Nefzger, C., Georges, C. & Asghari-Jafarabadi, M.
1/01/24 → 31/12/28
Project: Research
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The kinome 'at large' in cancer
Fleuren, E. D. G., Zhang, L., Wu, J. & Daly, R. J., Feb 2016, In: Nature Reviews Cancer. 16, 2, p. 83-98 16 p.Research output: Contribution to journal › Article › Research › peer-review
218 Citations (Scopus) -
Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes
Fleuren, E. D. G., Vlenterie, M., Van Der Graaf, W. T. A., Hillebrandt-Roeffen, M. H. S., Blackburn, J., Ma, X., Chan, H., Magias, M. C., Van Erp, A., Van Houdt, L., Cebeci, S. A. S., Van De Ven, A., Flucke, U. E., Heyer, E. E., Thomas, D. M., Lord, C. J., Marini, K. D., Vaghjiani, V., Mercer, T. R., Cain, J. E., & 3 others , 15 Aug 2017, In: Cancer Research. 77, 16, p. 4279-4292 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile35 Citations (Scopus) -
Homo- and heterotypic association regulates signaling by the SgK269/PEAK1 and SgK223 pseudokinases
Liu, L., Phua, Y. W., Lee, R. S., Ma, X., Jenkins, Y., Novy, K., Humphrey, E. S., Chan, H., Shearer, R., Ong, P. C., Dai, W., Saunders, D. N., Lucet, I. S. & Daly, R. J., 7 Oct 2016, In: Journal of Biological Chemistry. 291, 41, p. 21571-21583 13 p.Research output: Contribution to journal › Article › Research › peer-review
27 Citations (Scopus) -
Proteome-based molecular subtyping and therapeutic target prediction in gastric cancer
Hu, C., Song, J., Kwok, T., Nguyen, E. V., Shen, X. & Daly, R. J., Jun 2024, In: Molecular Oncology. 18, 6, p. 1437-1459 23 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
A Boolean-based machine learning framework identifies predictive biomarkers of HSP90-targeted therapy response in prostate cancer
Shin, S. Y., Centenera, M. M., Hodgson, J. T., Nguyen, E. V., Butler, L. M., Daly, R. J. & Nguyen, L. K., 19 Jan 2023, In: Frontiers in Molecular Biosciences. 10, 16 p., 1094321.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus)
Press/Media
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AI tool to boost genomic data analysis
Jiangning Song, Roger Daly & Jian Li
25/04/19
1 Media contribution
Press/Media: Research
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Bioinformatics tool to unearth new pointers to disease
Jiangning Song, Roger John Daly & Fuyi Li
10/07/18
1 Media contribution
Press/Media: Research
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New tool to speed up translation of genome sequences
Jiangning Song, Roger John Daly, Geoffrey Ian Bawtree Webb & Alexander Ian Smith
8/03/18
1 Media contribution
Press/Media: Research