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Professor Roger Daly relocated his laboratory to Monash University in March 2013, where he is currently Head of the Department of Biochemistry and Molecular Biology and Head of the Biomedicine Discovery Institute Cancer Program. Professor Daly is an internationally recognised expert in growth factor receptor signaling and its deregulation in cancer. Over the last 5 years he has established cutting-edge technology platforms in mass spectrometry-based proteomics and kinomics. These have been successfully applied to the characterisation of cancer signaling networks with the goal of identifing novel therapeutic targets and biomarkers.

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Monash teaching commitment

BCH3042 - Signalling from Bench to Bedside (3 Lectures)

BMS3021 - Molecular Mechanisms Underpinning Human Cancers (3 Lectures)

Research area keywords

  • Cancer
  • Cancer Cell Biology
  • Signal Transduction
  • Signalling pathways
  • Mass Spectrometry

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Projects 2009 2023

Research Output 1988 2019

108 Citations (Scopus)

The kinome 'at large' in cancer

Fleuren, E. D. G., Zhang, L., Wu, J. & Daly, R. J., Feb 2016, In : Nature Reviews Cancer. 16, 2, p. 83-98 16 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes

Fleuren, E. D. G., Vlenterie, M., Van Der Graaf, W. T. A., Hillebrandt-Roeffen, M. H. S., Blackburn, J., Ma, X., Chan, H., Magias, M. C., Van Erp, A., Van Houdt, L., Cebeci, S. A. S., Van De Ven, A., Flucke, U. E., Heyer, E. E., Thomas, D. M., Lord, C. J., Marini, K. D., Vaghjiani, V., Mercer, T. R., Cain, J. E. & 3 others, Wu, J., Versleijen-Jonkers, Y. M. H. & Daly, R. J., 15 Aug 2017, In : Cancer Research. 77, 16, p. 4279-4292 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Homo- and heterotypic association regulates signaling by the SgK269/PEAK1 and SgK223 pseudokinases

Liu, L., Phua, Y. W., Lee, R. S., Ma, X., Jenkins, Y., Novy, K., Humphrey, E. S., Chan, H., Shearer, R., Ong, P. C., Dai, W., Saunders, D. N., Lucet, I. S. & Daly, R. J., 7 Oct 2016, In : Journal of Biological Chemistry. 291, 41, p. 21571-21583 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

Lee, R. S., Zhang, L., Berger, A., Lawrence, M. G., Song, J., Niranjan, B., Davies, R. G., Lister, N. L., Sandhu, S. K., Rubin, M. A., Risbridger, G. P., Taylor, R. A., Rickman, D. S., Horvath, L. G. & Daly, R. J., 1 Apr 2019, In : Neoplasia. 21, 4, p. 389-400 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1 Citation (Scopus)

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

Ma, X., Zhang, L., Song, J., Nguyen, E., Lee, R. S., Rodgers, S. J., Li, F., Huang, C., Schittenhelm, R. B., Chan, H., Chheang, C., Wu, J., Brown, K. K., Mitchell, C. A., Simpson, K. J. & Daly, R. J., 17 Jan 2019, In : Nature Communications. 10, 1, 16 p., 296.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Press / Media