Projects per year
Personal profile
Biography
Robert studied Human Genetics at the University of Nottingham before moving to the Medical Research Council's Human Genetics Unit in Edinburgh to complete his PhD and begin his work using the zebrafish model system. He completed his PhD in 2003 and continued his research at the Victor Chang Cardiac Research Institute in Sydney and the Australian Regenerative Medicine Institute at Monash University. He joined the school as a lecturer and researcher in 2010.
Research interests
Robert's lab investigates neuromuscular disease, spanning the spectrum from identification of new disease genes, to determination of the underlying biological mechanism, and subsequently evaluation of potential therapies. The focus is on the identification of clinically translatable findings, aiding in the diagnosis and treatments of these conditions. We primarily use the zebrafish model to achieve these goals.
Our research target the universities research focus area of Health Sciences.
Lab Website: www.bryson-richardsonlab.org
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- myopathy
- muscle
- 3D and 4D imaging
- zebrafish
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Testing of a VUS in distal myopathy and neuropathy
Bryson-Richardson, R. & Miles, L.
1/05/24 → 30/06/26
Project: Research
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Establishment of a comprehensive rhabdomyolysis genetic diagnostic pipeline - a large cross-disciplinary Australian collaboration
Oates, E. (Primary Chief Investigator (PCI)), Tchan, M. C. (Chief Investigator (CI)), Bryson-Richardson, R. (Chief Investigator (CI)), Wilkins, M. R. (Chief Investigator (CI)), Yuen, M. (Chief Investigator (CI)), Parker, B. L. (Chief Investigator (CI)), Curmi, P. M. G. (Chief Investigator (CI)), Michie, K. (Chief Investigator (CI)), Cowley, M. J. (Chief Investigator (CI)), Needham, M. (Chief Investigator (CI)), Jones, K. J. (Chief Investigator (CI)), Kornberg, A. J. (Chief Investigator (CI)), Farrar, M. (Chief Investigator (CI)), Cairns, A. (Chief Investigator (CI)), Liang, C. (Chief Investigator (CI)), Simons, C. (Associate Investigator (AI)), Ravenscroft, G. (Associate Investigator (AI)), Davis, M. (Associate Investigator (AI)), Sampaio, H. (Associate Investigator (AI)), Ghaoui, R. (Associate Investigator (AI)), Mowat, D. (Associate Investigator (AI)), Young, H. (Associate Investigator (AI)), Woodcock, I. (Associate Investigator (AI)), Yiu, E. M. (Associate Investigator (AI)) & Vink, R. (Associate Investigator (AI))
1/06/23 → 6/08/27
Project: Research
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Investigating Mechanisms of Alcohol-Induced Heart Disease
Fatkin, D. (Primary Chief Investigator (PCI)), Farrell, M. P. (Chief Investigator (CI)), Niederer, S. (Chief Investigator (CI)), Bryson-Richardson, R. (Chief Investigator (CI)), Jabbour, A. (Chief Investigator (CI)), Giannoulatou, E. (Chief Investigator (CI)), Wong, C. X. (Chief Investigator (CI)), Turner, N. (Chief Investigator (CI)), Pouliopoulos, J. (Chief Investigator (CI)), Santiago, C. F. (Chief Investigator (CI)), Stubley, C. (Chief Investigator (CI)) & Johnson, R. (Chief Investigator (CI))
1/06/22 → …
Project: Research
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Advancing congenital and childhood-onset muscle disease diagnosis and treatment - a cross-disciplinary Australian collaboration
Oates, E. (Primary Chief Investigator (PCI)), Quinlan, K. G. R. (Chief Investigator (CI)), Wilkins, M. (Chief Investigator (CI)), Curmi, P. M. G. (Chief Investigator (CI)), Michie, K. (Chief Investigator (CI)), Bryson-Richardson, R. (Chief Investigator (CI)), Yuen, M. (Chief Investigator (CI)), Wilton, S. (Chief Investigator (CI)) & Ravenscroft, G. (Chief Investigator (CI))
1/04/22 → 31/03/26
Project: Research
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CRIMP: a CRISPR/Cas9 insertional mutagenesis protocol and toolkit
Miles, L. B., Calcinotto, V., Oveissi, S., Serrano, R. J., Sonntag, C., Mulia, O., Lee, C. & Bryson-Richardson, R. J., Dec 2024, In: Nature Communications. 15, 1, 11 p., 5011.Research output: Contribution to journal › Article › Other › peer-review
Open Access3 Citations (Scopus) -
Manipulation of Proteostasis Networks in Transgenic ZAAT Zebrafish via CRISPR–Cas9 Gene Editing
Fung, C., Miles, L. B., Bryson-Richardson, R. J. & Bird, P. I., 2024, Alpha-1 Antitrypsin: Methods and Protocols. Bristow , C. L. (ed.). New York NY USA: Humana Press, p. 19-32 14 p. (Methods in Molecular Biology; vol. 2750).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Mitochondrial abnormalities contribute to muscle weakness in a Dnajb6 deficient zebrafish model
McKaige, E. A., Lee, C., Calcinotto, V., Giri, S., Crawford, S., McGrath, M. J., Ramm, G. & Bryson-Richardson, R. J., 15 Jul 2024, In: Human Molecular Genetics. 33, 14, p. 1195-1206 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease
Donkervoort, S., van de Locht, M., Ronchi, D., Reunert, J., McLean, C. A., Zaki, M., Orbach, R., de Winter, J. M., Conijn, S., Hoomoedt, D., Neto, O. L. A., Magri, F., Viaene, A. N., Foley, A. R., Gorokhova, S., Bolduc, V., Hu, Y., Acquaye, N., Napoli, L. & Park, J. H. & 24 others, , 3 Apr 2024, In: Science Translational Medicine. 16, 741, 13 p., eadg2841.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Commercially available industry-relevant software in the education of genome variant curation
Vidor, C., Duivenvoorden, H. M., du Sart, D., Bryson-Richardson, R. J. & Hiscox, T., 24 Aug 2023, p. 72. 1 p.Research output: Contribution to conference › Abstract › peer-review