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Personal profile

Biography

Robert studied Human Genetics at the University of Nottingham before moving to the Medical Research Council's Human Genetics Unit in Edinburgh to complete his PhD and begin his work using the zebrafish model system. He completed his PhD in 2003 and continued his research at the Victor Chang Cardiac Research Institute in Sydney and the Australian Regenerative Medicine Institute at Monash University. He joined the school as a lecturer and researcher in 2010.

 

Research interests

Robert's lab investigates neuromuscular disease, spanning the spectrum from identification of new disease genes, to determination of the underlying biological mechanism, and subsequently evaluation of potential therapies. The focus is on the identification of clinically translatable findings, aiding in the diagnosis and treatments of these conditions. We primarily use the zebrafish model to achieve these goals.

Our research target the universities research focus area of Health Sciences. 

 

Lab Website: www.bryson-richardsonlab.org

Supervision interests

PhD projects are available investigating the genetic basis of neuromuscular disease and the underling biology leading to pathology. 

I am also seeking a motivated student interested in developing cryo-EM techniques for large samples. 

 

Research area keywords

  • myopathy
  • muscle
  • 3D and 4D imaging
  • zebrafish

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Projects

Research Output

BAG3P215L/KO Mice as a Model of BAG3P209L Myofibrillar Myopathy

Robertson, R., Conte, T. C., Dicaire, M. J., Rymar, V. V., Sadikot, A. F., Bryson-Richardson, R. J., Lavoie, J. N., O'Ferrall, E., Young, J. C. & Brais, B., Mar 2020, In : American Journal of Pathology. 190, 3, p. 554-562 9 p.

Research output: Contribution to journalArticleResearchpeer-review

KBTBD13 is an actin-binding protein that modulates muscle kinetics

De Winter, J. M., Molenaar, J. P., Yuen, M., Van Der Pijl, R., Shen, S., Conijn, S., Van De Locht, M., Willigenburg, M., Bogaards, S. J. P., Van Kleef, E. S. B., Lassche, S., Persson, M., Rassier, D. E., Sztal, T. E., Ruparelia, A. A., Oorschot, V., Ramm, G., Hall, T. E., Xiong, Z., Johnson, C. N. & 21 others, Li, F., Kiss, B., Lozano-Vidal, N., Boon, R. A., Marabita, M., Nogara, L., Blaauw, B., Rodenburg, R. J., Küsters, B., Doorduin, J., Beggs, A. H., Granzier, H., Campbell, K., Ma, W., Irving, T., Malfatti, E., Romero, N. B., Bryson-Richardson, R. J., Van Engelen, B. G. M., Voermans, N. C. & Ottenheijm, C. A. C., 3 Feb 2020, In : Journal of Clinical Investigation. 130, 2, p. 754-767 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

A transgenic zebrafish model of hepatocyte function in human Z α1-antitrypsin deficiency

Yip, E., Giousoh, A., Fung, C., Wilding, B., Prakash, M. D., Williams, C., Verkade, H., Bryson-Richardson, R. J. & Bird, P. I., 12 Jun 2019, In : Biological Chemistry. 400, 12, p. 1603-1616 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Linking life-history theory and metabolic theory explains the offspring size-temperature relationship

Pettersen, A. K., White, C. R., Bryson-Richardson, R. J. & Marshall, D., 7 Jan 2019, In : Ecology Letters. 22, 3, p. 518-526 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Advances in the Understanding of Skeletal Myopathies from Zebrafish Models

Baxter, E. C. & Bryson-Richardson, R. J., 11 Oct 2018, Zebrafish, Medaka, and Other Small Fishes: New Model Animals in Biology, Medicine, and Beyond. Hirata, H. & Iida, A. (eds.). Singapore: Springer, p. 151-183 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review