Projects per year
Personal profile
Biography
Dr Goldberg is a Gastroenterologist at Monash Health and a research fellow at School of Clinical Sciences. Dr Goldberg treats patients suffering from inflammatory bowel disease and is interested in developing novel treatments for this debilitation condition.
During her PhD at King’s College London (2019), Dr Goldberg worked to develop a regulatory T cell (Treg) based therapy for patients with Crohn’s Disease. This therapy uses the patients’ own immune cells to turn off the inflammation driving their disease. This novel treatment is currently a Phase 1 trial across the United Kingdom. Dr Goldberg has published her research in top tier Gastroenterology journals, including Gut, Gastroenterology and Nature Reviews Gastroenterology. She was the recipient of the British Society of Gastroenterology Best Scientific Abstract Award as well as the Society of Mucosal Immunology – Rising Stars in Mucosal Immunology award.
Since returning to Australia, Dr Goldberg has worked to form collaborative research networks to bring this paradigm changing therapy to the Australian patient population. Her work is currently supported by the school of clinical sciences career development fellowship and a Crohn’s and Colitis Australia Research Prize. As part of her clinical work, Dr Goldberg is an investigator on a number of industry led Phase 2/3 trials, thus always ensuring her patients have access to cutting edge therapies.
Research Interests
- Adaptive immunity in inflammatory bowel disease
- Innate immunity in inflammatory bowel disease
- Cell based therapies for inflammatory bowel disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Immunology and Mucosal Biology, PhD, Restoring Protective T cell Immunity in Crohn's Disease - Molecular Mechanisms and a Gut Specific Regulatory T cell Therapy , King's College London
Award Date: 1 May 2019
MBBS, University of Melbourne
Award Date: 14 Dec 2007
BMedSci, University of Melbourne
Award Date: 14 Dec 2007
External positions
Visiting Senior Lecturer, King's College London
Research area keywords
- Regulatory T cells
- inflammatory bowel disease
- cell therapies
- Inflammation
Collaborations and top research areas from the last five years
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Gastrointestinal-Restricted ALK5 Inhibitors for the Treatment of Intestinal Fibrosis
Flynn, B. (Primary Chief Investigator (PCI)), Goldberg, R. (Chief Investigator (CI)), Pitson, S. M. (Chief Investigator (CI)), Ooi, J. (Chief Investigator (CI)) & Rodent, K. K. (Chief Investigator (CI))
National Foundation for Medical Research and Innovation
1/03/24 → 1/09/25
Project: Research
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Achieving benefit without harm: a next-generation glucocorticoid replacement
Jones, S. (Primary Chief Investigator (PCI)), Morand, E. (Associate Investigator (AI)), Nicholson, S. E. (Associate Investigator (AI)), Russ, B. (Associate Investigator (AI)), Vincent, F. (Associate Investigator (AI)), Harris, J. (Associate Investigator (AI)), Moore, G. (Associate Investigator (AI)), Goldberg, R. (Associate Investigator (AI)), Turner, S. (Associate Investigator (AI)) & Rosenbluh, S. (Associate Investigator (AI))
1/01/22 → 31/12/25
Project: Research
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Antigen Specific Regulatory T Cell Therapy for Ulcerative Colitis
Goldberg, R. (Primary Chief Investigator (PCI))
13/11/23 → 13/12/24
Project: Research
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Ovalbumin Specific iTreg for the treatment of Inflammatory Bowel Disease
Goldberg, R. (Primary Chief Investigator (PCI)), Ooi, J. (Partner Investigator (PI)) & Zaph, C. (Partner Investigator (PI))
17/03/22 → 15/12/22
Project: Research
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Cell based regenerative therapy for inflammatory bowel disease
Goldberg, R. (Primary Chief Investigator (PCI))
7/06/21 → 6/06/22
Project: Research
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Vedolizumab and Ustekinumab Levels in Pregnant Women With Inflammatory Bowel Disease and Infants Exposed In Utero
Prentice, R., Flanagan, E., Wright, E. K., Gibson, P. R., Rosella, S., Rosella, O., Begun, J., An, Y. K., Lawrance, I. C., Kamm, M. A., Sparrow, M., Goldberg, R., Prideaux, L., Vogrin, S., Kiburg, K. V., Ross, A. L., Burns, M. & Bell, S. J., Jan 2025, In: Clinical Gastroenterology and Hepatology. 23, 1, p. 124-133.e7 17 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
A case of visceral leishmaniasis masquerading as autoimmune hepatitis
Ea, V., Papa, B. & Goldberg, R., Sept 2024, In: Medical Journal of Australia. 221, 6, p. 299-301 3 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
Colonic cytomegalovirus DNA detection by polymerase chain reaction does not influence outcomes in inflammatory bowel disease and immunosuppressed cohorts
Nguyen, P., Shrestha, A., Sane, N., Abeywickrama, D., Holt, D. Q., Bell, S., Moore, G. & Goldberg, R., Feb 2024, In: Internal Medicine Journal. 54, 2, p. 283-289 7 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Thiopurine Metabolite Shunting in Late Pregnancy Increases the Risk of Intrahepatic Cholestasis of Pregnancy in Women with Inflammatory Bowel Disease, and Can be Managed with Split Dosing
Prentice, R., Flanagan, E., Wright, E., Prideaux, L., Connell, W., Sparrow, M., De Cruz, P., Lust, M., Hardikar, W., Goldberg, R., Vogrin, S., Palmer, K., Ross, A., Burns, M., Greeve, T. & Bell, S., 1 Jul 2024, In: Journal of Crohn's and Colitis. 18, 7, p. 1081-1090 10 p.Research output: Contribution to journal › Article › Research › peer-review
2 Citations (Scopus) -
Thrombocytosis and Transaminitis in Infants Born to Women With Inflammatory Bowel Disease Is Associated With Exposure to Maternal Inflammation In Utero
Prentice, R. E., Flanagan, E. K., Wright, E. K., Hardikar, W., Ross, A. L., Burns, M., Prideaux, L., Connell, W. C., Sparrow, M., De Cruz, P. P., Lust, M., Goldberg, R., Vogrin, S., Greeve, T. & Bell, S. J., 5 Dec 2024, In: Inflammatory Bowel Diseases. 30, 12, p. 2323-2334 12 p.Research output: Contribution to journal › Article › Research › peer-review
Prizes
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School of Clinical Sciences Career Development Fellowship
Goldberg, R. (Recipient), 1 May 2019
Prize: Competitive Fellowships
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Janssen (Australia and New Zealand) (External organisation)
Goldberg, R. (Member)
Sept 2019 → …Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of an advisory panel/policy group/ board
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Australian Gastroenterology Week (AGW) 2019
Goldberg, R. (Session chair)
8 Sept 2019Activity: Participating in or organising an event types › Contribution to conference