Projects per year
Personal profile
Biography
I am Professor within the Department of Neuroscience at the Central Clinical School, with an internationally recognised laboratory for the study of neurodevelopmental plasticity. My laboratory uses extensive behavioural, epigenetic, imaging and neuropathological techniques to examine the influences of early experiences on long-term outcomes. We are particularly interested in understanding how early environmental manipulations (i.e. stress, drug exposure, diet) modify brain development and recovery from brain injury, as well as the risk for chronic pain and mental health disorders. In addition, we closely collaborate with the CCS departments of Gastroenterology and Immunology as part of the new GIN (Gastroenterology-Immunology-Neuroscience) initiative which is designed to further understand the gut-brain-immune axis and rapidly translate research from the bench to the bedside.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Neuroscience, PhD
Award Date: 21 Jun 2012
Forensic Molecular Biology, Masters
Award Date: 30 Aug 2007
Psychology, BSc
Award Date: 1 Jun 2005
Cellular, Molecular, and Microbial Biology, BSc
Research area keywords
- Mild traumatic brain injury
- Neurodevelopmental plasticity
- Concussion pathology
Network
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Brain injury in intimate partner violence: Insight into a silent pandemic
Shultz, S., O'Sullivan, M. J., Fitz-Gibbon, K., Meyer, S., van Donkelaar, P., Mychasiuk, R., McDonald, S., Law, M., Vivash, L., O'Brien, T., Ponsford, J., Jupp, B., Chen, B., Mitra, B. & Marks, J.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/22 → 31/12/24
Project: Research
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Neuroprotective effect of the combination of cannabidiol and isoflurane in mild traumatic brain injury
McDonald, S., Mychasiuk, R., Shultz, S. & Spitz, G.
15/02/21 → 15/02/22
Project: Research
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Testing of the effect of E2730 treatment on multimodality in-vivo biomarkers of GABAergic function in healthy rats and preclinical chronic epilepsy models
O'Brien, T., Kwan, P., Ali, I., Casillas-Espinosa, P., Jones, N., Jupp, B., Vivash, L., Wright, D., Mychasiuk, R. & Major, B.
22/10/20 → 21/10/21
Project: Research
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A high-fat high-sugar diet and adversity early in life modulate pain outcomes at the behavioural and molecular level in adolescent rats: The role of sex
Salberg, S., Yamakawa, G. R., Beveridge, J. K., Noel, M. & Mychasiuk, R., Feb 2023, In: Brain, Behavior, and Immunity. 108, p. 57-79 23 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Pre-existing Toxoplasma gondii infection increases susceptibility to pentylenetetrazol-induced seizures independent of traumatic brain injury in mice
Baker, T. L., Uboldi, A. D., Tonkin, C. J., Wright, D. K., Vo, A., Wilson, T., Mychasiuk, R., McDonald, S. J., Semple, B. D., Sun, M. & Shultz, S. R., 5 Jan 2023, In: Frontiers in Molecular Neuroscience. 15, 16 p., 1079097.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The Foundations for Chronic Low Back Pain Management may Start in Early Life. Exploring the Role of Caregiver Parental Leave on Future Low Back Pain in the Offspring
O'Hagan, E. T., Wallwork, S. B., Callander, E., Stanton, T. R. & Mychasiuk, R., 2023, (Accepted/In press) In: Journal of Pain. 7 p.Research output: Contribution to journal › Article › Other › peer-review
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Age matters: Microbiome depletion prior to repeat mild traumatic brain injury differentially alters microbial composition and function in adolescent and adult rats
Sgro, M., Iacono, G., Yamakawa, G. R., Kodila, Z. N., Marsland, B. J. & Mychasiuk, R., Nov 2022, In: PLoS ONE. 17, 11, 26 p., e0278259.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Choroid plexus function in neurological homeostasis and disorders: The awakening of the circadian clocks and orexins
Christensen, J., Li, C. & Mychasiuk, R., Jul 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 7, p. 1163–1175 13 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access7 Citations (Scopus)