1982 …2019
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Research Output 1982 2019

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 othersFailes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Cystathionine β -Synthase in Physiology and Cancer

Zhu, H., Blake, S., Chan, K. T., Pearson, R. B. & Kang, J., 28 Jun 2018, In : BioMed Research International. 2018, 11 p., 3205125.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

How the evolution of multicellularity set the stage for cancer

Trigos, A. S., Pearson, R. B., Papenfuss, A. T. & Goode, D. L., 16 Jan 2018, In : British Journal of Cancer. 118, 2, p. 145-152 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Kondrashova, O., Topp, M., Nesic, K., Lieschke, E., Ho, G. Y., Harrell, M. I., Zapparoli, G. V., Hadley, A., Holian, R., Boehm, E., Heong, V., Sanij, E., Pearson, R. B., Krais, J. J., Johnson, N., McNally, O., Ananda, S., Alsop, K., Hutt, K. J., Kaufmann, S. H. & 11 othersLin, K. K., Harding, T. C., Traficante, N., Australian Ovarian Cancer Study (AOCS), deFazio, A., McNeish, I. A., Bowtell, D. D., Swisher, E. M., Dobrovic, A., Wakefield, M. J. & Scott, C. L., 1 Dec 2018, In : Nature Communications. 9, 1, 16 p., 3970.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance

Martin, C. A., Cullinane, C., Kirby, L., Abuhammad, S., Lelliott, E. J., Waldeck, K., Young, R. J., Brajanovski, N., Cameron, D. P., Walker, R., Sanij, E., Poortinga, G., Hannan, R. D., Pearson, R. B., Hicks, R. J., McArthur, G. A. & Sheppard, K. E., 15 May 2018, In : International Journal of Cancer. 142, 10, p. 2139-2152 14 p.

Research output: Contribution to journalArticleResearchpeer-review