1982 …2019
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Research Output 1982 2019

1 Citation (Scopus)

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

AbuHammad, S., Cullinane, C., Martin, C., Bacolas, Z., Ward, T., Chen, H., Slater, A., Ardley, K., Kirby, L., Chan, K. T., Brajanovski, N., Smith, L. K., Rao, A. D., Lelliott, E. J., Kleinschmidt, M., Vergara, I. A., Papenfuss, A. T., Lau, P., Ghosh, P., Haupt, S. & 12 others, Haupt, Y., Sanij, E., Poortinga, G., Pearson, R. B., Falk, H., Curtis, D. J., Stupple, P., Devlin, M., Street, I., Davies, M. A., McArthur, G. A. & Sheppard, K. E., 3 Sep 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 36, p. 17990-18000 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Cystathionine β -Synthase in Physiology and Cancer

Zhu, H., Blake, S., Chan, K. T., Pearson, R. B. & Kang, J., 28 Jun 2018, In : BioMed Research International. 2018, 11 p., 3205125.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

How the evolution of multicellularity set the stage for cancer

Trigos, A. S., Pearson, R. B., Papenfuss, A. T. & Goode, D. L., 16 Jan 2018, In : British Journal of Cancer. 118, 2, p. 145-152 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Kondrashova, O., Topp, M., Nesic, K., Lieschke, E., Ho, G. Y., Harrell, M. I., Zapparoli, G. V., Hadley, A., Holian, R., Boehm, E., Heong, V., Sanij, E., Pearson, R. B., Krais, J. J., Johnson, N., McNally, O., Ananda, S., Alsop, K., Hutt, K. J., Kaufmann, S. H. & 11 others, Lin, K. K., Harding, T. C., Traficante, N., Australian Ovarian Cancer Study (AOCS), deFazio, A., McNeish, I. A., Bowtell, D. D., Swisher, E. M., Dobrovic, A., Wakefield, M. J. & Scott, C. L., 1 Dec 2018, In : Nature Communications. 9, 1, 16 p., 3970.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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