Projects per year
Professor A Richard Kitching is a nephrologist physician-scientist in the Centre for Inflammatory Diseases within the Department of Medicine. He heads a group working or autoimmune vasculitis, with a particular interest on how the immune system injures the kidney.
His research focuses on autoimmune vasculitis, conditions that often cause rapidly progressive inflammatory kidney disease (rapidly progressive glomerulonephritis). By understanding the involvement of leukocytes (white blood cells) in glomerulonephritis, an important cause of kidney disease, we will be able to develop and use more targeted and effective treatments. Professor Kitching combines his research with clinical practice in Nephrology. This clinical practice helps define important questions in the causes of immune kidney disease and how they can be better treated. His research program has established the role of pathogenic and protective cellular immunity in rapidly progressive glomerulonephritis, and defined the key parts of molecules (autoantigens) that cause disease so that antigen specific treatments are not possible.
The causes of severe rapidly progressive glomerulonephritis, important conditions that result in end stage kidney disease, are unclear. These diseases are usually due to autoimmune vasculitis, but unfortunately, current treatments are toxic and ineffective. Medications that are the current standard of care have significant toxic effects – and without a better understanding of how disease occurs, it will be difficult to develop new treatments. To use more specific biological and cellular therapies, we need to understand the critical steps in how the disease develops.
Professor Kitching's research is funded by NHMRC Project Grants, an NHMRC grant within a European Union Horizon 20/20 Consortium and an NHMRC Centre for Research Excellence. His publications include papers in Nature, Nature Medicine, PNAS, The Journal of Clinical Investigation, The Journal of Experimental Medicine, Nature Communications, Blood, The Journal of the American Society of Nephrology and Kidney International.
He heads the Monash Health Vasculitis Clinic and is Co-Chair of the Australian and New Zealand Society of Nephrology Research Advisory Committee. In 2018 he and colleagues established the ANZ Vasculitis Society (ANZVASC) to improve clinical care and education in vasculitis, and to assist in translating research discoveries into clinical practice.
For publications, please see
Richard Kitching works at Monash Health as a Nephrologist and Paediatric Nephrologist.
In Adult Nephrology his work is focussed on immune kidney conditions: glomerulonephrtis, vasculitis, lupus nephrits and transplantation. He leads the reserach intensive Monash Vasculitis Clinic,
In Paediatric Nephrology he works with his colleagues across the range of kidney conditions that affect children.
All his work is in the public system - he does not run a private practice.
Professor Kitching is available for consulting in the reserach areas of vasculitis, glomerulonephritis, and other forms of immune kidney disease.
Medicine, PhD, MONASH UNIVERSITY
14 Jul 1995 → 28 Jul 1999
Award Date: 28 Jul 1999
Medicine, MB ChB (with distinction), University of Otago
Award Date: 11 Dec 1987
Chair, Board of Directors, Australia and New Zealand Vasculitis Society (ANZVASC)
Nephrologist, Monash Health
Paediatric Nephrologist, Monash Health
Research area keywords
- Autoimmune Diseases
- T cells
- Personalised Immunology
- Regulatory T cells
1/01/19 → 31/12/22
Shochet, I. R. & Kitching, R.
5/02/18 → 4/02/21
Schochet, I. & Kitching, R.
5/02/18 → 4/02/21
Robson, K. J. & Kitching, R.
1/02/18 → 31/01/21
Ooi, J. D., Petersen, J., Tan, Y. H., Huynh, M., Willett, Z. J., Ramarathinam, S. H., Eggenhuizen, P. J., Loh, K. L., Watson, K. A., Gan, P. Y., Alikhan, M. A., Dudek, N. L., Handel, A., Hudson, B. G., Fugger, L., Power, D. A., Holt, S. G., Coates, P. T., Gregersen, J. W., Purcell, A. W. & 5 others, , 11 May 2017, In: Nature. 545, 7653, p. 243-247 5 p.
Research output: Contribution to journal › Article › Research › peer-review
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunityOoi, J. D., Jiang, J-H., Eggenhuizen, P. J., Chua, L. L., van Timmeren, M., Loh, K. L., O’Sullivan, K. M., Gan, P. Y., Zhong, Y., Tsyganov, K., Shochet, L. R., Ryan, J., Stegeman, C. A., Fugger, L., Reid, H. H., Rossjohn, J., Heeringa, P., Holdsworth, S. R., Peleg, A. Y. & Kitching, A. R., 29 Jul 2019, In: Nature Communications. 10, 1, 14 p., 3392.
Research output: Contribution to journal › Article › Research › peer-reviewOpen AccessFile
Recurrent membranous nephropathy after transplantation: donor antigen and HLA converge in defining riskRobson, K. J. & Kitching, A. R., Mar 2021, In: Kidney International. 99, 3, p. 545-548 4 p.
Research output: Contribution to journal › Comment / Debate › Other › peer-review
Kitching, A. R., Anders, H. J., Basu, N., Brouwer, E., Gordon, J., Jayne, D. R., Kullman, J., Lyons, P. A., Merkel, P. A., Savage, C. O. S., Specks, U. & Kain, R., 27 Aug 2020, In: Nature Reviews Disease Primers. 6, 1, 27 p., 71.
Research output: Contribution to journal › Review Article › Research › peer-review