Projects per year
Personal profile
Biography
I am an NHMRC Senior Research Fellow and a Research Group Leader at the Hudson Institute. After completing my PhD at the University of NSW in 1990, I moved to the Institut Pasteur (Paris) where I worked as postdoctoral fellow (1990-1994) and later as a tenured research scientist (1994-2004). In 2004, I returned to Australia to a teaching/research appointment in the Department of Microbiology, Monash University. I was subsequently recruited by the Hudson Institute in 2009.
My main research interests span the fields of Helicobacter pylori, NOD-like receptor proteins and bacterial membrane vesicles. My research has translated to important outcomes in H. pylori antibiotic resistance, pathogenesis, vaccine development and innate immunology. This research has been published in over 100 works in books and peer-review journals, including Cell Host Microb., Gastroenterol., Immunity, mBio, PNAS USA, Nat Immunol. and Nat Rev Immunol. My publications in peer-review journals have an average citation number of 58, with 27 of these publications having > 100 citations. My H-index is 43.
I have collaborated with and/or consulted for vaccine (Aventis Pasteur Vaccins, Acambis Inc, Ondek Pty Ltd) and pharmaceutical (Bayer Germany) companies. We are currently engaged in contract work with Aché Laboratorios Farmaceuticos, Brazil. I am on the editorial board of the journal Helicobacter and served on a Canadian H. pylori consensus panel to develop an evidence-based approach to the treatment of H. pylori infection in children and adolescents. Since 2009, I have chaired abstract review panels for the American Gastroenterological Association. I review abstracts for three leading conferences in the Helicobacter field, as well as manuscripts submitted to leading international journals (e.g. J Extracell Ves., Nature, Nat Commun., PLoS Pathogens) and grant applications submitted to domestic and international funding bodies e.g. NHMRC, ARC, ANR (France), DFG (Germany), NMRC (Singapore), Wellcome Trust (U. K.). I am a scientific committee member for the International Workshop on Pathogenesis and Host Response in Helicobacter infections.
Education/Academic qualification
Higher Education, Graduate Certificate, MONASH UNIVERSITY
2007 → 2009
Microbiology, Ph.D., A comparative study of the ureases from gastric and non-gastric Helicobacter spp., University of New South Wales (UNSW)
1986 → 1990
Microbiology, Honours equivalent, A study on chemotaxis and motility in Camplyobacter jejuni., University of New South Wales (UNSW)
1985
Microbiology & Biochemistry, B.App.Sc., University of Technology (UTS) Sydney
1981 → 1984
Research area keywords
- Helicobacter pylori
- Gastric (Stomach) Cancer
- Inflammation
- Innate immunity
- Digestive disease
- Membrane vesicles
- Exosomes
- Infectious Diseases
- inflammasome
- B cell lymphoma
- Nod-like receptor
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Combating Antimicrobial Resistance with Bismuth, Gallium and Indium
Andrews, P. (Primary Chief Investigator (PCI)), Dove, A. (Partner Investigator (PI)), Ferrero, R. (Chief Investigator (CI)) & Meagher, L. (Chief Investigator (CI))
1/07/22 → 1/12/26
Project: Research
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Identification of new molecular pathways in gastric B-cell lymphomagenesis
He, Y. (Primary Chief Investigator (PCI)) & Ferrero, R. (Supervisor)
Project: Research
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Unravelling the regulatory functions of NLRC5 in anti-cancer immunity
Ferrero, R. (Primary Chief Investigator (PCI)), Tong, D. (Chief Investigator (CI)), Kufer, T. (Chief Investigator (CI)) & Hatten, H. (Chief Investigator (CI))
15/02/23 → 14/02/25
Project: Research
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Innate immune cytosolic DNA sensors as novel pro-tumorigenic drivers in stomach cancer
Jenkins, B. (Primary Chief Investigator (PCI)), Ferrero, R. (Chief Investigator (CI)), Zavros, Y. (Chief Investigator (CI)), Thomas, P. (Chief Investigator (CI)) & Kumar, B. (Chief Investigator (CI))
1/07/22 → 30/06/25
Project: Research
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Defining a protective role for NLRC5 signalling in Helicobacter pylori disease
Ferrero, R. (Primary Chief Investigator (PCI)), Kufer, T. (Chief Investigator (CI)) & D'Elios, M. (Associate Investigator (AI))
1/01/22 → 31/12/25
Project: Research
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A more rapid method for transformation of Helicobacter pylori
Skene, C. D. & Ferrero, R. L., 25 Feb 2025, In: mSphere. 10, 2, 7 p., e0000525.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
BAFF Blockade Attenuates B Cell MALT Formation in Conditional Nlrc5-Deficient Mice With Helicobacter felis Infection
Tong, D., He, Y., Haile, S. A., Lee, Z., Le, L. H. M., Emery, J., Wray-McCann, G., Chonwerawong, M., Philpott, D. J., Hertzog, P. J., Schneider, P., Ferrero, R. L. & Ying, L., Feb 2025, In: European Journal of Immunology. 55, 2, 14 p., e202451355.Research output: Contribution to journal › Article › Research › peer-review
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Campylobacter jejuni extracellular vesicles harboring cytolethal distending toxin bind host cell glycans and induce cell cycle arrest in host cells
My Le, L. H., Elgamoudi, B., Colon, N., Cramond, A., Poly, F., Ying, L., Korolik, V. & Ferrero, R. L., Mar 2024, In: Microbiology Spectrum. 12, 3, p. 1-17 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access19 Link opens in a new tab Citations (Scopus) -
Cysteine and resistance to oxidative stress: implications for virulence and antibiotic resistance
Tikhomirova, A., Rahman, M. M., Kidd, S. P., Fererro, R. L. & Roujeinikova, A., Jan 2024, In: Trends in Microbiology. 32, 1, p. 93-104 12 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile63 Link opens in a new tab Citations (Scopus) -
Interleukin-18 produced by gastric epithelial cells protects against pre-neoplastic lesions in Helicobacter pylori infection in mice
Zhao, X., Tong, D. & Ferrero, R. L., 2024, In: Genes and Immunity. 25, 4, 2 p.Research output: Contribution to journal › Article › Other › peer-review
1 Link opens in a new tab Citation (Scopus)