Projects per year
Personal profile
Biography
I am an NHMRC Senior Research Fellow and a Research Group Leader at the Hudson Institute. After completing my PhD at the University of NSW in 1990, I moved to the Institut Pasteur (Paris) where I worked as postdoctoral fellow (1990-1994) and later as a tenured research scientist (1994-2004). In 2004, I returned to Australia to a teaching/research appointment in the Department of Microbiology, Monash University. I was subsequently recruited by the Hudson Institute in 2009.
My main research interests span the fields of Helicobacter pylori, NOD-like receptor proteins and bacterial membrane vesicles. My research has translated to important outcomes in H. pylori antibiotic resistance, pathogenesis, vaccine development and innate immunology. This research has been published in over 100 works in books and peer-review journals, including Cell Host Microb., Gastroenterol., Immunity, mBio, PNAS USA, Nat Immunol. and Nat Rev Immunol. My publications in peer-review journals have an average citation number of 58, with 27 of these publications having > 100 citations. My H-index is 43.
I have collaborated with and/or consulted for vaccine (Aventis Pasteur Vaccins, Acambis Inc, Ondek Pty Ltd) and pharmaceutical (Bayer Germany) companies. We are currently engaged in contract work with Aché Laboratorios Farmaceuticos, Brazil. I am on the editorial board of the journal Helicobacter and served on a Canadian H. pylori consensus panel to develop an evidence-based approach to the treatment of H. pylori infection in children and adolescents. Since 2009, I have chaired abstract review panels for the American Gastroenterological Association. I review abstracts for three leading conferences in the Helicobacter field, as well as manuscripts submitted to leading international journals (e.g. J Extracell Ves., Nature, Nat Commun., PLoS Pathogens) and grant applications submitted to domestic and international funding bodies e.g. NHMRC, ARC, ANR (France), DFG (Germany), NMRC (Singapore), Wellcome Trust (U. K.). I am a scientific committee member for the International Workshop on Pathogenesis and Host Response in Helicobacter infections.
Education/Academic qualification
Higher Education, Graduate Certificate, MONASH UNIVERSITY
2007 → 2009
Microbiology, Ph.D., University of New South Wales
1986 → 1990
Microbiology, Honours equivalent, University of New South Wales
1985
Microbiology & Biochemistry, B.App.Sc., NSW Institute of Technology (now UTS, Sydney)
1981 → 1984
Research area keywords
- Helicobacter pylori
- Gastric (Stomach) Cancer
- Inflammation
- Innate immunity
- Digestive disease
- Membrane vesicles
- Exosomes
- Infectious Diseases
- inflammasome
- B cell lymphoma
- Nod-like receptor
Network
Projects
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Bacterial vesicles transport their bioactive cargo to the host nucleus
11/01/21 → 10/01/24
Project: Research
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3D Light Sheet Fluorescent Microscopy system
Jenkin, G., Harper, I., Hooper, S., Nold, M., Hickey, M., Kitching, R., Loveland, K., Gargett, C., Ferrero, R. & Lim, R.
Monash University – Internal Department Contribution
1/01/18 → 31/12/18
Project: Research
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Acquisition of a state-of-the-art confocal microscope for imaging of live and fixed samples
Nold, M., Elgass, K., Hickey, M., Kitching, R., Wallace, E., Nikolic-Paterson, D., Wong, C., Loveland, K., Gargett, C., Hooper, S., Ferrero, R., Lim, R., Mansell, A. & Harper, I.
1/12/16 → 31/12/17
Project: Research
Research output
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Constitutive STAT3 Serine Phosphorylation Promotes Helicobacter-Mediated Gastric Disease
Balic, J. J., Saad, M. I., Dawson, R., West, A. J., McLeod, L., West, A. C., D'Costa, K., Deswaerte, V., Dev, A., Sievert, W., Gough, D. J., Bhathal, P. S., Ferrero, R. L. & Jenkins, B. J., Jun 2020, In : American Journal of Pathology. 190, 6, p. 1256-1270 15 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Innate Immune Molecule NLRC5 Protects Mice From Helicobacter-induced Formation of Gastric Lymphoid Tissue
Chonwerawong, M., Ferrand, J., Chaudhry, H. M., Higgins, C., Tran, L. S., Lim, S. S., Walker, M. M., Bhathal, P. S., Dev, A., Moore, G. T., Sievert, W., Jenkins, B. J., D'Elios, M. M., Philpott, D. J., Kufer, T. A. & Ferrero, R. L., Jul 2020, In : Gastroenterology. 159, 1, p. 169-182 22 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Anti-Helicobacter pylori activity of ethoxzolamide
Modak, J. K., Tikhomirova, A., Gorrell, R. J., Rahman, M. M., Kotsanas, D., Korman, T. M., Garcia-Bustos, J., Kwok, T., Ferrero, R. L., Supuran, C. T. & Roujeinikova, A., 1 Dec 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 1660-1667 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile10 Citations (Scopus) -
Complete genome sequence of Helicobacter pylori B128 7.13 and a single-step method for the generation of unmarked mutations
Dawson, E. M., Dunne, K. A., Richardson, E. J., Praszkier, J., Alfawaz, D., Woelfel, S., De Paoli, A., Chaudhry, H., Henderson, I. R., Ferrero, R. L. & Rossiter, A. E., 1 Aug 2019, In : Helicobacter. 24, 4, 10 p., e12587.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
NLRC5 deficiency has a moderate impact on immunodominant CD8 + T-cell responses during rotavirus infection of adult mice
Sun, T., Ferrero, R. L., Girardin, S. E., Gommerman, J. L. & Philpott, D. J., Jul 2019, In : Immunology and Cell Biology. 97, 6, p. 552-562 11 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus)