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Research Output 2005 2020

2020
1 Citation (Scopus)

Molecular signature of interleukin-22 in colon carcinoma cells and organoid models

Rudloff, I., Jardé, T., Bachmann, M., Elgass, K. D., Kerr, G., Engel, R., Richards, E., Oliva, K., Wilkins, S., McMurrick, P. J., Abud, H. E., Mühl, H. & Nold, M. F., Feb 2020, In : Translational Research. 216, p. 1-22 22 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
5 Citations (Scopus)

Coinfection with human cytomegalovirus genetic variants in transplant recipients and its impact on antiviral T cell immune reconstitution

Smith, C., Brennan, R. M., Tey, S. K., Smyth, M. J., Burrows, S. R., Miles, J. J., Hill, G. R. & Khanna, R., Aug 2016, In : Journal of Virology. 90, 16, p. 7497-7507 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
17 Citations (Scopus)

The impact of HLA class I and EBV latency-II antigen-specific CD8+ T cells on the pathogenesis of EBV+ Hodgkin lymphoma

Jones, K., Wockner, L., Brennan, R. M., Keane, C., Chattopadhyay, P. K., Roederer, M., Price, D. A., Cole, D. K., Hassan, B., Beck, K., Gottlieb, D., Ritchie, D. S., Seymour, J. F., Vari, F., Crooks, P., Burrows, S. R. & Gandhi, M. K., Feb 2016, In : Clinical and Experimental Immunology. 183, 2, p. 206-220 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014

Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire

Brennan, R. M., Burrows, J. M., Elliott, T., Neller, M. A., Gras, S., Rossjohn, J., Miles, J. J. & Burrows, S., 2014, In : British Journal of Haematology. 166, 1, p. 142 - 153 12 p.

Research output: Contribution to journalLetterOther

9 Citations (Scopus)

Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire

Smith, C., Gras, S., Brennan, R. M., Bird, N. L., Valkenburg, S. A., Twist, K-A., Burrows, J. M., Miles, J. J., Chambers, D. C., Bell, S. C., Campbell, S. B., Kedzierska, K., Burrows, S. R., Rossjohn, J. & Khanna, R., 2014, In : Scientific Reports. 4, 10 p., 3993.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
3 Citations (Scopus)

Multivariate analysis using high definition flow cytometry reveals distinct T cell repertoires between the fetal-maternal interface and the peripheral blood

Neller, M. A., Santner-Nanan, B., Brennan, R. M., Hsu, P., Joung, S., Nanan, R., Burrows, S. R. & Miles, J. J., 5 Feb 2014, In : Frontiers in Immunology. 5, 6 p., 33.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2013
31 Citations (Scopus)

HLA peptide length preferences control CD8+ T cell responses

Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland, A. D., Chen, Z., Sullivan, L. C., Burrows, J. M., Miles, J. J., Brennan, R. M., Gras, S., Khanna, R., Brooks, A., McCluskey, J., Purcell, A. W., Rossjohn, J. & Burrows, S. R., 2013, In : Journal of Immunology. 191, 2, p. 561-571 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
21 Citations (Scopus)

The impact of a large and frequent deletion in the human TCR beta locus on antiviral immunity

Brennan, R. M., Petersen, J., Neller, M. A., Miles, J. J., Burrows, J. M., Smith, C., McCluskey, J., Khanna, R., Rossjohn, J. & Burrows, S. R., 2012, In : Journal of Immunology. 188, 6, p. 2742 - 2748 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
17 Citations (Scopus)

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

Miles, J. J., Thammanichanond, D., Moneer, S., Nivarthi, U. K., Kjer-Nielsen, L., Tracy, S. L., Aitken, C. K., Brennan, R. M., Zeng, W., Marquart, L., Jackson, D., Burrows, S. R., Bowden, D. S., Torresi, J., Hellard, M., Rossjohn, J., McCluskey, J. & Bharadwaj, M., 2011, In : Journal of Immunology. 186, 2, p. 901 - 912 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
58 Citations (Scopus)

Allelic polymorphism in the T cell receptor and its impact on immune responses

Gras, S., Chen, Z., Miles, J. J., Liu, Y. C., Bell, M. J., Sullivan, L. C., Kjer-Nielsen, L., Brennan, R. M., Burrows, J. M., Neller, M. A., Khanna, R., Purcell, A. W., Brooks, A. G., McCluskey, J., Rossjohn, J. & Burrows, S. R., 2010, In : Journal of Experimental Medicine. 207, 7, p. 1555 - 1567 13 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

Burrows, S. R., Chen, Z., Archbold, J. K., Tynan, F. E., Beddoe, T. C., Kjer-Nielsen, L., Miles, J. J., Khanna, R., Moss, D. J., Liu, Y. C., Gras, S., Kostenko, L., Brennan, R. M., Clements, C. S., Brooks, A. G., Purcell, A. W., McCluskey, J. & Rossjohn, J., 2010, In : Proceedings of the National Academy of Sciences. 107, 23, p. 10608 - 10613 6 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Strains of Epstein-Barr virus infecting multiple sclerosis patients

Brennan, R. M., Burrows, J. M., Bell, M. J., Bromham, L., Csurhes, P. A., Lenarczyk, A., Sverndal, J., Klintenstedt, J., Pender, M. P. & Burrows, S. R., 1 Jan 2010, In : Multiple Sclerosis. 16, 6, p. 643-651 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
72 Citations (Scopus)

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

Archbold, J. K., Macdonald, W. A., Gras, S., Ely, L. K., Miles, J. J., Bell, M. J., Brennan, R. M., Beddoe, T. C., Wilce, M. C. J., Clements, C. S., Purcell, A. W., McCluskey, J., Burrows, S. R. & Rossjohn, J., 2009, In : Journal of Experimental Medicine. 206, 1, p. 209 - 219 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

T cell receptor bias in humans

Miles, J. J., Brennan, R. M. & Burrows, S. R., 1 Jun 2009, In : Current Immunology Reviews. 5, 1, p. 10-21 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

26 Citations (Scopus)

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length

Bell, M. J., Burrows, J. M., Brennan, R. M., Miles, J. J., Tellam, J., McCluskey, J., Rossjohn, J., Khanna, R. & Burrows, S. R., 2009, In : Molecular Immunology. 46, 8-9, p. 1911 - 1917 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
22 Citations (Scopus)

A mechanism for the HLA-A*01 associated risk for EBV + hodgkin lymphoma and infectious mononucleosis

Brennan, R. M. & Burrows, S. R., 15 Sep 2008, In : Blood. 112, 6, p. 2589-2590 2 p.

Research output: Contribution to journalLetterOtherpeer-review

21 Citations (Scopus)

Preferential binding of unusually long peptides to MHC class I and its influence on the selection of target peptides for T cell recognition

Burrows, J. M., Bell, M. J., Brennan, R., Miles, J. J., Khanna, R. & Burrows, S. R., 1 Mar 2008, In : Molecular Immunology. 45, 6, p. 1818-1824 7 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Widespread sequence variation in Epstein-Barr virus nuclear antigen 1 influences the antiviral T cell response

Bell, M. J., Brennan, R., Miles, J. J., Moss, D. J., Burrows, J. M. & Burrows, S. R., 1 Jun 2008, In : Journal of Infectious Diseases. 197, 11, p. 1594-1597 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2007
15 Citations (Scopus)

Predictable αβ T-cell receptor selection toward an HLA-B*3501-restricted human cytomegalovirus epitope

Brennan, R. M., Miles, J. J., Silins, S. L., Bell, M. J., Burrows, J. M. & Burrows, S. R., 1 Jul 2007, In : Journal of Virology. 81, 13, p. 7269-7273 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
40 Citations (Scopus)

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

Burrows, J. M., Wynn, K. K., Tynan, F. E., Archbold, J. K., Miles, J. J., Bell, M. J., Brennan, R. M., Walker, S., McCluskey, J., Rossjohn, J., Khanna, R. & Burrows, S., 2007, In : European Journal of Immunology. 37, 4, p. 946 - 953 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
38 Citations (Scopus)

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

Archbold, J. K., Macdonald, W. A., Miles, J. J., Brennan, R. M., Kjer-Nielsen, L., McCluskey, J., Burrows, S. & Rossjohn, J., 2006, In : Journal of Biological Chemistry. 281, 45, p. 34324 - 34332 9 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

TCRalpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope

Miles, J. J., Borg, N. A., Brennan, R. M., Tynan, F. E., Kjer-Nielsen, L., Silins, S. L., Bell, M. J., Burrows, J. M., McCluskey, J., Rossjohn, J. & Burrows, S. R., 2006, In : Journal of Immunology. 177, 10, p. 6804 - 6814 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Predicting the human T cell receptor choice before viral infection; Facts learnt from primary infection

Miles, J. J., McCluskey, J. (ed.), Tait, B. (ed.), Borg, N., Holdsworth, R. (ed.), Tynan, F. E., Kjer-Nielsen, L., Christiansen, F. (ed.), Elhassen, D., Silins, S. L., Burrows, J. M., Brennan, R. M., Purcell, A. W., McCluskey, J. & Rossjohn, J., 2005, p. 493 - 493. 1 p.

Research output: Contribution to conferenceAbstract