Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Uncovering novel mechanisms of treatment resistance in lethal colorectal cancers
Abud, H., Engel, R., McMurrick, P., Schittenhelm, R., Lum, C. D. R. & Archer, S.
1/01/23 → 31/12/25
Project: Research
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Deciphering the crosstalk between aging and colorectal cancer
Fennell, L., Engel, R., Rosenbluh, S., Whitehall, V. L. J. & Powell, D.
1/01/23 → 31/12/24
Project: Research
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Personalising cancer medicine part II: Expanding the organoid program to include treatment-exposed metastatic colorectal cancer
Engel, R., Mendis, S., McMurrick, P. & Abud, H.
1/07/21 → 30/06/22
Project: Research
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Using patient-derived organoids to guide the nonsurgical “watch and wait” approach for rectal cancer
Engel, R., McMurrick, P. & Abud, H.
1/07/18 → 30/06/19
Project: Research
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Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential
Nefzger, C. M., Jardé, T., Srivastava, A., Schroeder, J., Rossello, F. J., Horvay, K., Prasko, M., Paynter, J. M., Chen, J., Weng, C. F., Sun, Y. B. Y., Liu, X., Chan, E., Deshpande, N., Chen, X., Li, Y. J., Pflueger, J., Engel, R. M., Knaupp, A. S., Tsyganov, K., & 5 others, Dec 2022, In: npj Regenerative Medicine. 7, 1, 8 p., 31.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Modeling colorectal cancer: A bio-resource of 50 patient-derived organoid lines
Engel, R. M., Jardé, T., Oliva, K., Kerr, G., Chan, W. H., Hlavca, S., Nickless, D., Archer, S. K., Yap, R., Ranchod, P., Bell, S., Niap, A., Koulis, C., Chong, A., Wilkins, S., Dale, T. C., Hollins, A. J., McMurrick, P. J. & Abud, H. E., May 2022, In: Journal of Gastroenterology and Hepatology. 37, 5, p. 898-907 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Mileto, S. J., Jardé, T., Childress, K. O., Jensen, J. L., Rogers, A. P., Kerr, G., Hutton, M. L., Sheedlo, M. J., Bloch, S. C., Shupe, J. A., Horvay, K., Flores, T., Engel, R., Wilkins, S., McMurrick, P. J., Lacy, D. B., Abud, H. E. & Lyras, D., 7 Apr 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 14, p. 8064-8073 10 p.Research output: Contribution to journal › Article › Research › peer-review
35 Citations (Scopus) -
Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
Jardé, T., Chan, W. H., Rossello, F. J., Kaur Kahlon, T., Theocharous, M., Kurian Arackal, T., Flores, T., Giraud, M., Richards, E., Chan, E., Kerr, G., Engel, R. M., Prasko, M., Donoghue, J. F., Abe, S., Phesse, T. J., Nefzger, C. M., McMurrick, P. J., Powell, D. R., Daly, R. J., & 2 others, 1 Oct 2020, In: Cell Stem Cell. 27, 4, p. 646-662 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile48 Citations (Scopus) -
Molecular signature of interleukin-22 in colon carcinoma cells and organoid models
Rudloff, I., Jardé, T., Bachmann, M., Elgass, K. D., Kerr, G., Engel, R., Richards, E., Oliva, K., Wilkins, S., McMurrick, P. J., Abud, H. E., Mühl, H. & Nold, M. F., Feb 2020, In: Translational Research. 216, p. 1-22 22 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus)