1971 …2020

Research output per year

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Research Output

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Article

Mapping the chemical and sequence space of the ShKT superfamily

Shafee, T., Mitchell, M. L. & Norton, R. S., 1 Jul 2019, In : Toxicon. 165, p. 95-102 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Marine blue-green algae have a unique osmoregulatory system

Mackay, M. A., Norton, R. S. & Borowitzka, L. J., Apr 1983, In : Marine Biology. 73, 3, p. 301-307 7 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Merozoite surface protein 2 of Plasmodium falciparum: Expression, structure, dynamics, and fibril formation of the conserved N-terminal domain

Low, A., Chandrashekaran, I. R., Adda, C. G., Yao, S., Sabo, J. K., Zhang, X., Soetopo, A., Anders, R. F. & Norton, R. S., Sep 2007, In : Biopolymers. 87, 1, p. 12-22 11 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Metabolic changes induced during adaptation of Saccharomyces cerevisiae to a water stress

Singh, K. K. & Norton, R. S., Jul 1991, In : Archives of Microbiology. 156, 1, p. 38-42 5 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Metabolic studies of the protozoan parasite, Crithidia luciliae, using proton nuclear magnetic resonance spectroscopy

Gilroy, F. V., Edwards, M. R., Norton, R. S. & O'Sullivan, W. J., 1988, In : Molecular and Biochemical Parasitology. 31, 2, p. 107-115 9 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Mimotopes of apical membrane antigen 1: Structures of phage-derived peptides recognized by the inhibitory monoclonal antibody 4G2dc1 and design of a more active analogue

Sabo, J. K., Keizer, D. W., Feng, Z. P., Casey, J. L., Parisi, K., Coley, A. M., Foley, M. & Norton, R. S., Jan 2007, In : Infection and Immunity. 75, 1, p. 61-73 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Modulation of the aggregation of an amyloidogenic sequence by flanking-disordered region in the intrinsically disordered antigen merozoite surface protein 2

Zhang, W., Zhang, J., MacRaild, C. A., Norton, R. S., Anders, R. F. & Zhang, X., 2019, In : European Biophysics Journal. 48, 1, p. 99-110 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide

Wang, G., MacRaild, C. A., Mohanty, B., Mobli, M., Cowieson, N. P., Anders, R. F., Simpson, J. S., McGowan, S., Norton, R. S. & Scanlon, M., 2014, In : PLoS ONE. 9, 10, p. 1-12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
10 Citations (Scopus)

Molecular insights into the interaction between the SPRY domain-containing SOCS box protein SPSB2 and peptides based on the binding motif from iNOS

Leung, E., Mulcair, M., Yap, S., Nicholson, S. E., Scanlon, M. & Norton, R., 2017, In : Australian Journal of Chemistry. 70, 2, p. 191-200 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

mu-Conotoxins as leads in the development of new analgesics

Norton, R. S., 2010, In : Molecules. 15, 4, p. 2825 - 2844 20 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Multiple conformations of the sea anemone polypeptide anthopleurin‐A in solution

Scanlon, M. J. & Norton, R. S., 1994, In : Protein Science. 3, 7, p. 1121-1124 4 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution

Yao, S., Young, I., Norton, R. & Murphy, J., 2011, In : Biochemistry. 50, 13, p. 2464 - 2477 14 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Mutating a critical lysine in ShK toxin alters its binding configuration in the pore - Vestibule region of the voltage-gated potassium channel, Kv1.3

Lanigan, M. D., Kalman, K., Lefievre, Y., Pennington, M. W., Chandy, K. G. & Norton, R. S., 8 Oct 2002, In : Biochemistry. 41, 40, p. 11963-11971 9 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Natural‐Abundance 13C Nuclear‐Magnetic‐Resonance Study of Toxin II from Anemonia sulcata

NORTON, R. S., ZWICK, J. & BÉRESS, L., 1980, In : European Journal of Biochemistry. 113, 1, p. 75-83 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Natural abundance carbon-13 nuclear magnetic resonance study of anthopleurin-A, a cardiac stimulant from the sea anemone Anthopleura xanthogrammica

Norton, R. S. & Norton, T. R., 1979, In : The Journal of Biological Chemistry. 254, 20, p. 10220-10226 7 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation

Wacklin, H. P., Bremec, B. B., Moulin, M., Rojko, N., Haertlein, M., Forsyth, T., Anderluh, G. & Norton, R., 1 Apr 2016, In : Biochimica et Biophysica Acta - Biomembranes. 1858, 4, p. 640-652 13 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

NMR Spectroscopy of Peptides and Proteins: Practical Considerations

Hinds, M. G. & Norton, R. S., 1997, In : Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 7, 3, p. 315-331 17 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

NMR studies of a murine-human chimera of leukaemia inhibitory factor (LIF). Comparison with human LIF

Maurer, T., Smith, D. K., Owczarek, C. M., Layton, M. J., Zhang, J. G., Nicola, N. A. & Norton, R. S., 1994, In : Growth Factors. 11, 4, p. 271-276 6 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

NMR studies of the solution properties of recombinant murine interleukin-6

Morton, C. J., Bai, H., Hammacher, A., Norton, R. S., Simpson, R. J. & Mabbutt, B. C., 12 Jun 1995, In : Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1249, 2, p. 189-203 15 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels

Bulaj, G., West, P., Garrett, J., Watkins, M., Zhang, M-M., Norton, R., Smith, B., Yoshikami, D. & Olivera, B., 2005, In : Biochemistry. 44, 19, p. 7259 - 7265 7 p.

Research output: Contribution to journalArticleResearchpeer-review

94 Citations (Scopus)

N-terminally extended analogues of the K+ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3

Chang, S. C., Huq, R., Chhabra, S., Beeton, C., Pennington, M. W., Smith, B. J. & Norton, R. S., 2015, In : FEBS Journal. 282, 12, p. 2247-2259 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Observation of drug metabolites and endogenous compounds in human urine by 1h nuclear magnetic resonance spectroscopy

Coleman, M. D. & Norton, R. S., 1986, In : Xenobiotica. 16, 1, p. 69-77 9 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Organic osmoregulatory solutes in cyanobacteria

Mackay, M. A., Norton, R. S. & Borowitzka, L. J., 1984, In : Journal of General Microbiology. 130, 9, p. 2177-2191 15 p.

Research output: Contribution to journalArticleResearchpeer-review

198 Citations (Scopus)
19 Citations (Scopus)

Peptide Inhibitors of the Malaria Surface Protein, Apical Membrane Antigen 1: Identification of Key Binding Residues

Lee, E., Yao, S., Sabo, J., Fairlie, W., Stevenson, R., Harris, K., Anders, R., Foley, M. & Norton, R., 2011, In : Biopolymers. 95, 5 (SI), p. 354 - 364 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Peptide self-association in aqueous trifluoroethanol monitored by pulsed field gradient NMR diffusion measurements

Yao, S., Howlett, G. J. & Norton, R. S., 2000, In : Journal of Biomolecular NMR. 16, 2, p. 109-119 11 p.

Research output: Contribution to journalArticleResearchpeer-review

105 Citations (Scopus)

Peptides targeting voltage-gated calcium channels

Norton, R. S. & McDonough, S. I., 2008, In : Current Pharmaceutical Design. 14, 24, p. 2480 - 2491 12 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Peptide therapeutics from venom: Current status and potential

Pennington, M. W., Czerwinski, A. & Norton, R. S., 1 Jun 2018, In : Bioorganic & Medicinal Chemistry. 26, 10, p. 2738-2758 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
61 Citations (Scopus)

Peroxidase catalysed cross-Linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

Mai, K., Smith, N., Feng, Z-P., Katrib, M., Slapetova, I., Wallach, M., Luxford, C., Davies, M., Zhang, X., Norton, R. & Belli, S., 2011, In : International Journal for Parasitology. 41, 11, p. 1157 - 1164 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Photochemically induced dynamic nuclear polarisation NMR study of the aromatic residues of sea‐anemone polypeptide cardiac stimulants

NORTON, R. S., BERESS, L., STOB, S., BOELENS, R. & KAPTEIN, R., 1986, In : European Journal of Biochemistry. 157, 2, p. 343-346 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
64 Citations (Scopus)

Polypeptide ω-conotoxin GVIA as a basis for new analgesic and neuroprotective agents

Norton, R. S., Pallaghy, P. K., Baell, J. B., Wright, C. E., Lew, M. J. & Angus, J. A., 1999, In : Drug Development Research. 46, 3-4, p. 206-218 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Potassium channel gating: Not an open and shut case

Norton, R. S. & Gulbis, J. M., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 17, p. 7623 - 7624 2 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Potassium channel modulation by a toxin domain in matrix metalloprotease 23

Rangaraju, S., Khoo, K. K., Feng, Z-P., Crossley, G., Nugent, D., Khaytin, I., Chi, V., Pham, C., Calabresi, P., Pennington, M. W., Norton, R. S. & Chandy, K. G., 2010, In : The Journal of Biological Chemistry. 285, 12, p. 9124 - 9136 13 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Predicting disordered regions in proteins based on decision trees of reduced amino acid composition

Han, P., Zhang, X., Norton, R. S. & Feng, Z. P., Nov 2006, In : Journal of Computational Biology. 13, 9, p. 1579-1590 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Preparation and characterization of a biologically active spin-labeled sea anemone toxin

Monks, S. A., Norton, R. S., Curtain, C. C. & Berliner, L. J., 1996, In : Journal of Protein Chemistry. 15, 5, p. 427-434 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Probing the correlation between insulin activity and structural stability through introduction of the rigid A6 –A11 bond

Ong, S. C., Belgi, A., Van Lierop, B., Delaine, C., Andrikopoulos, S., MacRaild, C. A., Norton, R. S., Haworth, N. L., Robinson, A. J. & Forbes, B. E., 27 Jul 2018, In : The Journal of Biological Chemistry. 293, 30, p. 11928-11943 16 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog

Tanner, M. R., Tajhya, R. B., Huq, R., Gehrmann, E. J., Rodarte, K. E., Atik, M. A., Norton, R. S., Pennington, M. W. & Beeton, C., 1 Jul 2017, In : Clinical Immunology. 180, p. 45-57 13 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold

Devine, S., Mulcair, M., Debono, C., Leung, E. W. W., Nissink, J. W. M., Lim, S. S., Chandrashekaran, I. R., Vazirani, M., Mohanty, B., Simpson, J. S., Baell, J. B., Scammells, P. J., Norton, R. S. & Scanlon, M., 2015, In : Journal of Medicinal Chemistry. 58, 3, p. 1205 - 1214 10 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Protein effective rotational correlation times from translational self-diffusion coefficients measured by PFG-NMR

Yao, S., Babon, J. J. & Norton, R. S., Aug 2008, In : Biophysical Chemistry. 136, 2-3, p. 145-151 7 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Proton‐Magnetic‐Resonance Spectroscopic Study of the Histidine Residues of Bovine α‐Lactalbumin

Bradbury, J. H. & Norton, R. S., 1975, In : European Journal of Biochemistry. 53, 2, p. 387-396 10 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Proton nmr relaxation study of the dynamics of anthopleurin‐A in solution

Torda, A. E. & Norton, R. S., 1989, In : Biopolymers. 28, 3, p. 703-716 14 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Pulmonary delivery of the Kv1.3-blocking peptide HsTX1[R14A] for the treatment of autoimmune diseases

Jin, L., Zhou, Q. T., Chan, H-K., Larson, I. C., Pennington, M. W., Morales, R. A. V., Boyd, B. J., Norton, R. S. & Nicolazzo, J. A., 1 Feb 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 650-656 7 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Purification and characterisation of proteins with cardiac stimulatory and haemolytic activity from the anemone Actinia tenebrosa

Norton, R. S., Bobek, G., Ivanov, J. O., Thomson, M., Fiala-Beer, E., Moritz, R. L. & Simpson, R. J., 1990, In : Toxicon. 28, 1, p. 29-41 13 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Purification and characterization of ciguatoxins from moray eel (Lycodontis javanicus, Muraenidae)

Lewis, R. J., Sellin, M., Poli, M. A., Norton, R. S., MacLeod, J. K. & Sheil, M. M., 1991, In : Toxicon. 29, 9, p. 1115-1127 13 p.

Research output: Contribution to journalArticleResearchpeer-review

235 Citations (Scopus)

Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning

Harris, K. S., Casey, J. L., Coley, A. M., Karas, J., Sabo, J. K., Tan, Y. Y., Dolezal, O., Norton, R. S., Hughes, A. B., Scanlon, D. & Foley, M., 2009, In : The Journal of Biological Chemistry. 284, 14, p. 9361 - 9371 11 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

RASP: Rapid and robust backbone chemical shift assignments from protein structure

MacRaild, C. A. & Norton, R. S., 2014, In : Journal of Biomolecular NMR. 58, 3, p. 155 - 163 9 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Recombinant protein vaccines against the asexual blood-stages of Plasmodium falciparum

Anders, R. F., Adda, C. G., Foley, M. & Norton, R. S., 1 Jan 2010, In : Human Vaccines. 6, 1, p. 39 - 53 15 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction

Yap, B. K., Harjani, J. R., Leung, E. W. W., Nicholson, S. E., Scanlon, M. J., Chalmers, D. K., Thompson, P. E., Baell, J. B. & Norton, R. S., 1 Mar 2016, In : FEBS Letters. 590, 6, p. 696-704 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Refined solution structure of ω-conotoxin GVIA: Implications for calcium channel binding

Pallaghy, P. K. & Norton, R. S., 1999, In : Journal of Peptide Research. 53, 3, p. 343-351 9 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)