Raymond Norton

Professor

1971 …2021
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Research Output 1971 2019

1998

Shk-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide

Kalman, K., Pennington, M. W., Lanigan, M. D., Nguyen, A., Rauer, H., Mahnir, V., Paschetto, K., Kem, W. R., Grissmer, S., Gutman, G. A., Christian, E. P., Cahalan, M. D., Norton, R. S. & Chandy, K. G., 4 Dec 1998, In : Journal of Biological Chemistry. 273, 49, p. 32697-32707 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of leukemia inhibitory factor

Hinds, M. G., Maurer, T., Zhang, J. G., Nicola, N. A. & Norton, R. S., 29 May 1998, In : Journal of Biological Chemistry. 273, 22, p. 13738-13745 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of peptides from HIV-1 Vpr protein that cause membrane permeabilization and growth arrest

Yao, S., Torres, A. M., Azad, A. A., Macreadie, I. G. & Norton, R. S., 1998, In : Journal of Peptide Science. 4, 7, p. 426-435 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure and function of peptide and protein toxins from marine organisms

Norton, R. S., 1998, In : Journal of Toxicology - Toxin Reviews. 17, 2, p. 99-130 32 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The cystine knot structure of ion channel toxins and related polypeptides

Norton, R. S. & Pallaghy, P. K., Nov 1998, In : Toxicon. 36, 11, p. 1573-1583 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1997

NMR Spectroscopy of Peptides and Proteins: Practical Considerations

Hinds, M. G. & Norton, R. S., 1997, In : Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 7, 3, p. 315-331 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Resonance assignments, secondary structure and topology of leukaemia inhibitory factor in solution

Hinds, M. G., Maurer, T., Zhang, J. G., Nicola, N. A. & Norton, R. S., 1997, In : Journal of Biomolecular NMR. 9, 2, p. 113-126 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Roles of histidine 31 and tryptophan 34 in the structure, self- association, and folding of murine interleukin-6

Matthews, J. M., Ward, L. D., Hammacher, A., Norton, R. S. & Simpson, R. J., 20 May 1997, In : Biochemistry. 36, 20, p. 6187-6196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of a polypeptide from the N terminus of the HIV protein Nef

Barnham, K. J., Monks, S. A., Hinds, M. G., Azad, A. A. & Norton, R. S., 20 May 1997, In : Biochemistry. 36, 20, p. 5970-5980 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus

Pallaghy, P. K., Alewood, D., Alewood, P. F. & Norton, R. S., 15 Dec 1997, In : FEBS Letters. 419, 2-3, p. 191-196 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure-function relationships of ω-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine- substituted analogues

Lew, M. J., Flinn, J. P., Pallaghy, P. K., Murphy, R., Whorlow, S. L., Wright, C. E., Norton, R. S. & Angus, J. A., 2 May 1997, In : Journal of Biological Chemistry. 272, 18, p. 12014-12023 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: A helical hairpin cross-linked by disulphide bonding

Barnham, K. J., Dyke, T. R., Kem, W. R. & Norton, R. S., 23 May 1997, In : Journal of Molecular Biology. 268, 5, p. 886-902 17 p.

Research output: Contribution to journalArticleResearchpeer-review

1996

Preparation and characterization of a biologically active spin-labeled sea anemone toxin

Monks, S. A., Norton, R. S., Curtain, C. C. & Berliner, L. J., 1996, In : Journal of Protein Chemistry. 15, 5, p. 427-434 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of human neuropeptide Y

Monks, S. A., Karagianis, G., Howlett, G. J. & Norton, R. S., 1996, In : Journal of Biomolecular NMR. 8, 4, p. 379-390 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone

Tudor, J. E., Pallaghy, P. K., Pennington, M. W. & Norton, R. S., 1996, In : Nature Structural Biology. 3, 4, p. 317-320 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin

Dyke, T. R., Duggan, B. M., Pennington, M. W., Byrnes, M. E., Kem, W. R. & Norton, R. S., 4 Jan 1996, In : Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1292, 1, p. 31-38 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1995

Chemical modification of cationic groups in the polypeptide cardiac stimulant anthopleurin-A

Gould, A. R. & Norton, R. S., 1995, In : Toxicon. 33, 2, p. 187-199 13 p.

Research output: Contribution to journalArticleResearchpeer-review

NMR studies of the solution properties of recombinant murine interleukin-6

Morton, C. J., Bai, H., Hammacher, A., Norton, R. S., Simpson, R. J. & Mabbutt, B. C., 12 Jun 1995, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1249, 2, p. 189-203 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution properties of Escherichia coli-expressed VH domain of anti-neuraminidase antibody NC41

Kortt, A. A., Guthrie, R. E., Hinds, M. G., Power, B. E., Ivancic, N., Caldwell, J. B., Gruen, L. C., Norton, R. S. & Hudson, P. J., Apr 1995, In : Journal of Protein Chemistry. 14, 3, p. 167-178 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of a polypeptide containing four heptad repeat units from a merozoite surface antigen of Plasmodium falciparum

Mulhern, T. D., Norton, R. S., Howlett, G. J., Reid, G. E., Simpson, R. J., McColl, D. J., Anders, R. F. & Mulhern, T. D., 1995, In : Biochemistry. 34, 11, p. 3479-3491 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of human insulin-like growthfactor II. Relationship to receptor and binding protein interactions

Torres, A. M., Forbes, B. E., Aplin, S. E., Wallace, J. C., Francise, G. L. & Norton, R. S., 1995, In : Journal of Molecular Biology. 248, 2, p. 385-401 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A

Monks, S. A., Pallaghy, P. K., Scanlon, M. J. & Norton, R. S., 1995, In : Structure. 3, 8, p. 791-803 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Three-Dimensional Structure in Solution of the Polypeptide Cardiac Stimulant Anthopleurin-A

Pallaghy, P. K., Scanlon, M. J., Monks, S. A. & Norton, R. S., 1995, In : Biochemistry. 34, 11, p. 3782-3794 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1994

A common structural motif incorporating a cystine knot and a triple‐stranded β‐sheet in toxic and inhibitory polypeptides

Pallaghy, P. K., Norton, R. S., Nielsen, K. J. & Craik, D. J., 1994, In : Protein Science. 3, 10, p. 1833-1839 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Homology modelling and 1H NMR studies of human leukaemia inhibitory factor

Smith, D. K., Treutlein, H. R., Maurer, T., Owczarek, C. M., Layton, M. J., Nicola, N. A. & Norton, R. S., 22 Aug 1994, In : FEBS Letters. 350, 2-3, p. 275-280 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone

Monks, S. A., Gould, A. R., Lumley, P. E., Alewood, P. F., Kem, W. R., Goss, N. H. & Norton, R. S., 20 Jul 1994, In : Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1207, 1, p. 93-101 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Multiple conformations of the sea anemone polypeptide anthopleurin‐A in solution

Scanlon, M. J. & Norton, R. S., 1994, In : Protein Science. 3, 7, p. 1121-1124 4 p.

Research output: Contribution to journalArticleResearchpeer-review

NMR spectroscopy of peptides and proteins.

Hinds, M. G. & Norton, R. S., 1994, In : Methods in molecular biology (Clifton, N.J.). 36, p. 131-154 24 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

NMR studies of a murine-human chimera of leukaemia inhibitory factor (LIF). Comparison with human LIF

Maurer, T., Smith, D. K., Owczarek, C. M., Layton, M. J., Zhang, J. G., Nicola, N. A. & Norton, R. S., 1994, In : Growth Factors. 11, 4, p. 271-276 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Solution structure of synthetic peptides corresponding to the C‐terminal helix of interleukin‐6

MORTON, C. J., SIMPSON, R. J. & NORTON, R. S., 1994, In : European Journal of Biochemistry. 219, 1-2, p. 97-107 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of the cardiac inotropic polypeptide anthopleurin‐A

PENNINGTON, MICHAEL. W., ZADENBERG, INNA., BYRNES, MICHAEL. E., NORTON, RAYMOND. S. & KEM, WILLIAM. R., 1994, In : International Journal of Peptide and Protein Research. 43, 5, p. 463-470 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Three-Dimensional Structure in Solution of Neurotoxin III from the Sea Anemone Anemonia sulcata

Manoleras, N. & Norton, R. S., 1 Sep 1994, In : Biochemistry. 33, 37, p. 11051-11061 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1993

1H-n.M.R. Study of the solution properties and secondary structure of neurotoxin III from the sea anemone Anemonia sulcata

Norton, R. S., Cross, K., Braach-Maksvytis, V. & Wachter, E., 15 Jul 1993, In : Biochemical Journal. 293, 2, p. 545-551 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ciguatoxin-2 is a diastereomer of ciguatoxin-3

Lewis, R. J., Norton, R. S., Brereton, I. M. & Eccles, C. D., 1993, In : Toxicon. 31, 5, p. 637-643 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Refined structure in solution of the sea anemone neurotoxin ShI

Wilcox, G. R., Fogh, R. H. & Norton, R. S., 1993, In : Journal of Biological Chemistry. 268, 33, p. 24707-24719 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of the C‐terminus in the activity, conformation, and stability of interleukin‐6

Ward, L. D., Hammacher, A., Zhang, JG. G., Morton, C. J., Simpson, R. J., Weinstock, J., Yasukawa, K. & Norton, R. S., 1993, In : Protein Science. 2, 9, p. 1472-1481 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Sequential1H-NMR assignments of neurotoxin III from the sea anemone Heteractis macrodactylus and structural comparison with related toxins

Hinds, M. G. & Norton, R. S., Jun 1993, In : Journal of Protein Chemistry. 12, 3, p. 371-378 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Three-dimensional structure in solution of the calcium channel blocker ω-conotoxin

Pallaghy, P. K., Duggan, B. M., Pennington, M. W. & Norton, R. S., 20 Nov 1993, In : Journal of Molecular Biology. 234, 2, p. 405-420 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1992

1H‐NMR study of neurotoxin B‐IV from the marine worm Cerebratulus lacteus Solution properties, sequence‐specific resonance assignments, secondary structure and global fold

HANSEN, P. E., KEM, W. R., BIEBER, A. L. & NORTON, R. S., 1992, In : European Journal of Biochemistry. 210, 1, p. 231-240 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Linear and cyclic peptide analogues of the polypeptide cardiac stimulant, anthopleurin‐A: 1H‐NMR and biological activity studies

GOULD, A. R., MABBUTT, B. C., LLEWELLYN, L. E., GOSS, N. H. & NORTON, R. S., 1992, In : European Journal of Biochemistry. 206, 3, p. 641-651 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Relationship between the cytolysins tenebrosin-C from Actinia tenebrosa and equinatoxin II from Actinia equina

Norton, R. S., Maček, P., Reid, G. E. & Simpson, R. J., 1992, In : Toxicon. 30, 1, p. 13-23 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Spectral processing methods for the removal of t1 noise and solvent artifacts from NMR spectra

Manoleras, N. & Norton, R. S., Sep 1992, In : Journal of Biomolecular NMR. 2, 5, p. 485-494 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1991

Binding of the sea anemone polypeptide BDS II to the voltage-gated sodium channel

Llewellyn, L. E. & Norton, R. S., 1991, In : Biochemistry International. 24, 5, p. 937-946 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolic changes induced during adaptation of Saccharomyces cerevisiae to a water stress

Singh, K. K. & Norton, R. S., Jul 1991, In : Archives of Microbiology. 156, 1, p. 38-42 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Purification and characterization of ciguatoxins from moray eel (Lycodontis javanicus, Muraenidae)

Lewis, R. J., Sellin, M., Poli, M. A., Norton, R. S., MacLeod, J. K. & Sheil, M. M., 1991, In : Toxicon. 29, 9, p. 1115-1127 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel

Norton, R. S., 1991, In : Toxicon. 29, 9, p. 1051-1084 34 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1990

A 31P nuclear magnetic resonance study of Crithidia luciliae

Grote, R., Edwards, M. R., Norton, R. S. & O'Sullivan, W. J., 1990, In : Molecular and Biochemical Parasitology. 42, 1, p. 109-117 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Biochemical and pharmacological studies of the mechanism of action of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone, Actinia tenebrosa

Galettis, P. & Norton, R. S., 1990, In : Toxicon. 28, 6, p. 695-706 12 p.

Research output: Contribution to journalArticleResearchpeer-review