Personal profile
Biography
Associate Professor Rangi Kandane-Rathnayake is a Senior Researcher in the Rheumatology Research Group, School of Clinical Sciences at Monash Health (SCS), and the Scientific Director of the Asia Pacific Lupus Collaboration (APLC). She is an experienced biostatistician-epidemiologist in public health and clinical research with an outstanding track record in registry sciences and longitudinal data modelling. She has worked in several clinical quality registries, including the Australia and New Zealand Haemostasis Registry (ANZHR), Registry of Kidney Diseases (ROKD), and the Australian Bleeding Disorders Registry (ABDR) of the National Blood Authority (NBA) in collaboration with the Australian Haemophilia Centre Director’s Organisation (AHCDO). Her work has been published in many disciplines, including respiratory medicine, haematology, nephrology, and rheumatology.
Associate Professor Kandane-Rathnayake’s overarching research goal is to improve outcomes for individuals living with systemic lupus erythematosus (SLE)—a chronic, incurable, multisystem autoimmune disease that disproportionately affects young women and remains among the top ten causes of death in this group. She currently leads multiple research projects focused on understanding the burden of comorbidities and their impact on long-term outcomes in SLE, lupus nephritis, health economics, and health-related quality of life.
Related Links:
- Asia Pacific Lupus Collaboration
- Lupus and Arthritis Research Group
Education/Academic qualification
Biostatistics, Pgrad.Dip, Post-graduate diploma in biostatistics , MONASH UNIVERSITY
Award Date: 30 Nov 2019
Molecular Epidemiology, PhD, The associations between serum cytokines and allergic diseases, University of Melbourne
Award Date: 15 Oct 2010
Biomedical Sciences, BBMed (Hons), Bachelor of Biomedical Sciences with 1st class Honours in immunology , MONASH UNIVERSITY
Award Date: 30 Nov 2003
Research area keywords
- SLE
- Outcomes
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 15 Life on Land
Collaborations and top research areas from the last five years
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Comparison of outcomes between patients with severe refractory Systemic Lupus Erythematosus (srSLE) in the Asia Pacific Lupus Collaboration (APLC) cohort receiving standard of care (SoC) treatment versus srSLE patients of the CYTB323G12101 trial treated with YTB323, a CD19 CAR-T cell therapy.
Morand, E. (Primary Chief Investigator (PCI)) & Kandane-Rathnayake, R. (Chief Investigator (CI))
3/06/25 → 2/06/26
Project: Research
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Severe refractory SLE patients in the Asia Pacific Lupus Collaboration
Kandane-Rathnayake, R. (Primary Chief Investigator (PCI)), Morand, E. (Associate Investigator (AI)) & Hoi, A. (Associate Investigator (AI))
18/09/23 → 17/09/24
Project: Research
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Treatment patterns and outcomes of SLE patients with active nephritis
Kandane-Rathnayake, R. (Primary Chief Investigator (PCI))
10/01/23 → 30/12/24
Project: Research
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Retrospective analysis of T2T endpoint achievement in SLE
Morand, E. (Chief Investigator (CI)) & Kandane-Rathnayake, R. (Partner Investigator (PI))
1/01/23 → 1/09/24
Project: Research
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The burden of organ damage in SLE in the APLC - Systemic lupus erythematosus (SLE) in Asia Pacific Lupus Collaboration (APLC) – the burden of organ damage (LTOD)
Kandane-Rathnayake, R. (Primary Chief Investigator (PCI)) & Morand, E. (Chief Investigator (CI))
GlaxoSmithKline (GSK) United States
30/05/22 → 31/07/23
Project: Research
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Prevalence, Treatment Patterns, and Outcomes Among Australian SLE Patients With Inadequately Controlled Disease Activity
Hoi, A. Y. B., Koelmeyer, R., Oon, S., Goldblatt, F., O'Neill, S., Golder, V., Nikpour, M., Morand, E. F. & Kandane-Rathnayake, R., Jan 2026, In: International Journal of Rheumatic Diseases. 29, 1, 5 p., e70549.Research output: Contribution to journal › Letter › Research › peer-review
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Association of lupus low disease activity state and remission with reduced organ damage and flare in systemic lupus erythematosus patients with high disease activity: a multi-national, longitudinal cohort study
Kandane-Rathnayake, R., Golder, V., Louthrenoo, W., Chen, Y. H., Cho, J., Lateef, A., Hamijoyo, L., Luo, S. F., Wu, Y. J. J., Navarra, S. V., Zamora, L., Li, Z., Sockalingam, S., Katsumata, Y., Harigai, M., Hao, Y., Zhang, Z., Basnayake, B. M. D. B., Chan, M. & Kikuchi, J. & 18 others, , May 2025, In: Rheumatology. 64, 5, p. 2741-2748 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
Domains for inclusion in a novel Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE): results of a modified Delphi study
Connelly, K., Koelmeyer, R., Ayton, D., May, J., Gregory, K., Eades, L. E., Barallon, R., Kandane-Rathnayake, R., Golder, V., Anzum, A., Mydin, M., Akther, M., Friedman, A., Askanase, A. D., Aranow, C., Vital, E., Pons-Estel, G., Brunner, H., Kalunian, K. & Dantata, K. & 33 others, , 6 May 2025, In: Lupus Science & Medicine. 12, 1, 14 p., e001484.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Frequency and Determinants of Flare and Persistently Active Disease in a Large Multinational Prospective Lupus Cohort
Hao, Y., Hansen, D., Louthrenoo, W., Chen, Y. H., Cho, J., Lateef, A., Hamijoyo, L., Luo, S. F., Wu, Y. J., Navarra, S., Zamora, L., Li, Z., Sockalingam, S., Katsumata, Y., Harigai, M., Ji, L., Zhang, Z., Chan, M., Kikuchi, J. & Takeuchi, T. & 19 others, , Mar 2025, In: ACR Open Rheumatology. 7, 3, 9 p., e70007.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Informing trial measurement in systemic lupus erythematosus: Frequency of domain-specific disease activity in a multinational cohort
Barallon, R., Connelly, K., Golder, V., Louthrenoo, W., Chen, Y.-H., Cho, J., Lateef, A., Hamijoyo, L., Luo, S.-F., Wu, Y. J. J., Navarra, S., Zamora, L., Li, Z., Sockalingam, S., Katsumata, Y., Harigai, M., Hao, Y., Zhang, Z., Chan, M. & Kikuchi, J. & 18 others, , 8 Jul 2025, In: Lupus Science & Medicine. 12, 2, 8 p., e001574.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Link opens in a new tab Citation (Scopus)
Prizes
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Paper selected for the Best of Immunology & Cell Biology (ICB)/ Clinical and Translational Immunology (CTI) Workshop at the 2019 Australian & New Zealand Society for Immunology (ASI) Annual Scientific Meeting
Vincent, F. (Recipient), Harris, J. (Recipient), Morand, E. (Recipient), Sahhar, J. (Recipient), Ngian, G. (Recipient), Kandane-Rathnayake, R. (Recipient), Lang, T. (Recipient), Lin, E. (Recipient) & Mende, R. (Recipient), 11 Dec 2019
Prize: Prize (including medals and awards)