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Personal profile

Biography

Dr. Bhusal is a Postdoctoral Research Fellow in the Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute (BDI) at Monash University. He completed Bachelor in pharmacy from Pokhara University (Nepal). After completion of his Bachelor's degree, he worked in a pharmaceutical company in Nepal for more than a year then secured a scholarship to pursue his Master’s degree in Pharmaceutical chemistry at Wonkwang University (South Korea). After his Master’s degree, He worked as a lecturer, undergraduate research supervisor and research coordinator in a college affiliated to Pokhara University for more than three years (Nepal). During that period, he co-founded a small pharmaceutical manufacturing (generics) company, demonstrating his entrepreneurial prowess. Ram earned his Ph.D. at The University of Auckland (New Zealand) in the discipline of chemical biology under the auspices of the competitive University of Auckland Doctoral Scholarship.

Dr. Bhusal is experienced in chemical synthesis, molecular biology techniques, the production and purification of recombinant proteins, the binding and kinetic assays of proteins using various biophysical techniques, and the crystallization of proteins and structure determination.

Currently, Dr. Bhusal’s project involves characterizing a novel family of tick proteins (evasins) that target chemokines to suppress inflammation. His long-term career interest centers on investigating biochemical mechanisms in the context of infectious disease and the host immune response.

Education/Academic qualification

Chemical Biology, PhD, University of Auckland

1 Oct 201429 Oct 2018

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Research Output 2010 2019

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

Bhusal, R. P., Jiao, W., Kwai, B. X. C., Reynisson, J., Collins, A. J., Sperry, J., Bashiri, G. & Leung, I. K. H., 11 Oct 2019, In : Nature Communications. 10, 1, 7 p., 4639.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Antipyretic, Antinociceptive, and Anti-Inflammatory Activities from Pogostemon benghalensis Leaf Extract in Experimental Wister Rats

Aryal, S., Adhikari, B., Panthi, K., Aryal, P., Mallik, S. K., Bhusal, R. P., Salehi, B., Setzer, W. N., Sharifi-Rad, J. & Koirala, N., 20 Sep 2019, In : Medicines. 6, 4, 11 p., 96.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines

Bhusal, R. P., Eaton, J. R. O., Chowdhury, S. T., Power, C. A., Proudfoot, A. E. I., Stone, M. J. & Bhattacharya, S., 1 Nov 2019, (Accepted/In press) In : Trends in Biochemical Sciences. 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses

Bhusal, R. P., Foster, S. R. & Stone, M. J., 11 Oct 2019, (Accepted/In press) In : Protein Science. 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Development of NMR and thermal shift assays for the evaluation of: Mycobacterium tuberculosis isocitrate lyase inhibitors

Bhusal, R. P., Patel, K., Kwai, B. X. C., Swartjes, A., Bashiri, G., Reynisson, J., Sperry, J. & Leung, I. K. H., 1 Jan 2017, In : MedChemComm. 8, 11, p. 2155-2163 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Prizes

Faculty Bridging Postdoctoral Fellow

Ram Bhusal (Recipient), Jul 2019

Prize: Competitive Fellowships