Projects per year
Personal profile
Biography
Dr. Bhusal is a Postdoctoral Research Fellow in the Department of Biochemistry and Molecular Biology and Biomedicine Discovery Institute (BDI) at Monash University. He completed Bachelor in pharmacy from Pokhara University (Nepal). After completion of his Bachelor's degree, he worked in a pharmaceutical company in Nepal for more than a year then secured a scholarship to pursue his Master’s degree in Pharmaceutical chemistry at Wonkwang University (South Korea). After his Master’s degree, He worked as a lecturer, undergraduate research supervisor and research coordinator in a college affiliated to Pokhara University for more than three years (Nepal). During that period, he co-founded a small pharmaceutical manufacturing (generics) company, demonstrating his entrepreneurial prowess. Ram earned his Ph.D. at The University of Auckland (New Zealand) in the discipline of chemical biology under the auspices of the competitive University of Auckland Doctoral Scholarship.
Dr. Bhusal is experienced in chemical synthesis, molecular biology techniques, the production and purification of recombinant proteins, the binding and kinetic assays of proteins using various biophysical techniques, and the crystallization of proteins and structure determination.
Currently, Dr. Bhusal’s project involves characterizing a novel family of tick proteins (evasins) that target chemokines to suppress inflammation. His long-term career interest centers on investigating biochemical mechanisms in the context of infectious disease and the host immune response.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Chemical Biology, PhD, Biochemical and structural studies of Mycobacterium tuberculosis isocitrate lyase , University of Auckland
1 Oct 2014 → 29 Oct 2018
Award Date: 1 May 2019
Collaborations and top research areas from the last five years
Projects
- 1 Not started
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Harnessing ticks' tricks to develop therapies for inflammatory diseases
1/01/24 → 31/12/28
Project: Research
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Design rules of plant-based yoghurt-mimic: Formulation, functionality, sensory profile and nutritional value
Dhakal, D., Younas, T., Bhusal, R. P., Devkota, L., Henry, C. J. & Dhital, S., Sept 2023, In: Food Hydrocolloids. 142, 21 p., 108786.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access3 Citations (Scopus) -
Mycobacterium tuberculosis Rv1916 is an Acetyl-CoA-Binding Protein
Huang, E. Y. W., Kwai, B. X. C., Bhusal, R. P., Bashiri, G. & Leung, I. K. H., 13 Jul 2023, In: ChemBioChem. 24, 14, 7 p., e202300162.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
A metabolic perspective into antimicrobial tolerance and resistance
Bhusal, R. P., Barr, J. J. & Subedi, D., Mar 2022, In: The Lancet Microbe. 3, 3, p. e160-e161 2 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access3 Citations (Scopus) -
Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases
Bhusal, R. P., Aryal, P., Devkota, S. R., Pokhrel, R., Gunzburg, M. J., Foster, S. R., Lim, H. D., Payne, R. J., Wilce, M. C. J. & Stone, M. J., 1 Mar 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 9, 7 p., e2122105119.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity
Aryal, P., Devkota, S. R., Jeevarajah, D., Law, R., Payne, R. J., Bhusal, R. P. & Stone, M. J., Oct 2022, In: Journal of Biological Chemistry. 298, 10, 11 p., 102382.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)
Prizes
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Australian Peptide Conference 2022 - Travel Award
Bhusal, Ram (Recipient), 2022
Prize: Prize (including medals and awards)
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File
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Biomedicine Discovery Institute Travel Grant.
Bhusal, Ram (Recipient), 2021
Prize: Prize (including medals and awards)
File -
Diversity Equity and Inclusion Travel Award-The Protein Society Annual Symposium
Bhusal, Ram (Recipient), 2022
Prize: Prize (including medals and awards)
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Faculty Bridging Postdoctoral Fellowship
Bhusal, Ram (Recipient), Jul 2019
Prize: Competitive Fellowships