Projects per year
Personal profile
Biography
Ralf studied Biochemistry at the University of Bayreuth, Germany, and received his PhD from the University of Zurich, Switzerland, in 2009 for his work on cell cycle regulation and the composition of centromeres and kinetochores in Drosophila melanogaster.
After his PhD, he joined the group of Prof. Dr. Ernst Hafen at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. In close collaboration with the group of Prof. Dr. Ruedi Aebersold, he identified and validated novel components of the insulin receptor / target of rapamycin (InR/TOR) pathway using mass spectrometric approaches in combination with biochemical assays.
In 2012, Ralf was awarded a Swiss National Foundation (SNF) Fellowship for Prospective Researchers and joined the group of Prof. Dr. Anthony Purcell at Monash University in Melbourne, Australia. During that time, he utilized high-resolution mass spectrometry to study the onset and progression of a variety of clinically relevant diseases known as spondyloarthropathies. Because of his work, Ralf was awarded with a SFGBM (Swiss Foundation for Grants in Biology and Medicine) Fellowship for Advanced Researchers in 2013.
In 2016, Ralf was appointed as the Director of the Monash Biomedical Proteomics Platform to provide mass spectrometric expertise to researchers and the broader community.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Designing precision dietary therapies for inherited metabolic disorders through nutriphenomics
Johnson, T. (Primary Chief Investigator (PCI)), Piper, M. (Chief Investigator (CI)), Solon-Biet, S. (Chief Investigator (CI)), Dworkin, S. (Chief Investigator (CI)), He, Z. (Chief Investigator (CI)), Christodoulou, J. (Associate Investigator (AI)), Schittenhelm, R. (Associate Investigator (AI)), Imlach, W. (Associate Investigator (AI)) & Schwarz, G. (Associate Investigator (AI))
1/03/25 → 31/12/28
Project: Research
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Building a national capability for single cell proteomics for Australia
Schittenhelm, R. (Primary Chief Investigator (PCI))
Monash University – Internal University Contribution
1/01/25 → 31/12/25
Project: Research
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Understanding the metabolic landscape in the human kidney in diabetes
Coughlan, M. (Primary Chief Investigator (PCI)), Watt, M. J. (Associate Investigator (AI)), Stroud, D. A. (Associate Investigator (AI)), Ramm, G. (Associate Investigator (AI)), Schittenhelm, R. (Associate Investigator (AI)), Lazarou, M. (Associate Investigator (AI)), McLean, C. (Associate Investigator (AI)), Lawton, P. (Associate Investigator (AI)) & Ekinci, E. (Associate Investigator (AI))
1/01/24 → 31/12/28
Project: Research
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Drug Target Identification Platform
Creek, D. (Primary Chief Investigator (PCI)), Avery, V. M. (Chief Investigator (CI)), Pitson, S. M. (Chief Investigator (CI)), George, A. J. (Chief Investigator (CI)), Olechnowicz, S. (Chief Investigator (CI)), Baell, J. (Chief Investigator (CI)), Schittenhelm, R. (Chief Investigator (CI)), Li, J. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Stupple, P. (Chief Investigator (CI)), Drinkwater, C. (Chief Investigator (CI)), Flynn, B. (Chief Investigator (CI)), Brouwer, K. (Chief Investigator (CI)), Arndt, G. (Chief Investigator (CI)) & Newman, S. (Chief Investigator (CI))
Department of Health and Aged Care (Australia)
30/06/23 → 6/12/28
Project: Research
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Preventing a nephron deficit in premature offspring
Bertram, J. (Primary Chief Investigator (PCI)), Cullen-McEwen, L. (Chief Investigator (CI)), Charlton, J. (Chief Investigator (CI)), Simpson, S. J. (Associate Investigator (AI)), Solon-Biet, S. (Associate Investigator (AI)), Rose, A. (Associate Investigator (AI)), Schittenhelm, R. (Associate Investigator (AI)), Barlow, C. (Associate Investigator (AI)), Combes, A. (Associate Investigator (AI)), Tan, K. (Associate Investigator (AI)), Johnstone, L. (Associate Investigator (AI)), Wlodek, M. (Associate Investigator (AI)) & Stanford, K. I. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients
Yang, C., Camargo Tavares, L., Lee, H.-C., Steele, J. R., Ribeiro, R. V., Beale, A. L., Yiallourou, S., Carrington, M. J., Kaye, D. M., Head, G. A., Schittenhelm, R. B. & Marques, F. Z., 2025, In: Gut Microbes. 17, 1, 20 p., 2441356.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy
Campelj, D., Timpani, C., Spiesberger, G., Formosa, L., Steele, J., Zhang, H., Schittenhelm, R., Leow, L., Goodman, C. & Rybalka, E., Jun 2025, In: Journal of Cachexia, Sarcopenia and Muscle. 16, 3, 14 p., e13849.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Highly stable bacteriophages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria
Jati, A. (Leading Author), Li, Y., Mu, A., Thung, T. Y., Chen, H., Steele, J., Lee, H., Schittenhelm, R., Zhou, T., Short, F. L., Dunstan, R. A. (Leading Author) & Lithgow, T. (Leading Author), 16 Jul 2025, In: npj Viruses. 3, 1, 13 p., 56.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration
Jacques, M., Landen, S., Sharples, A. P., Garnham, A., Schittenhelm, R., Steele, J., Heikkinen, A., Sillanpää, E., Ollikainen, M., Broatch, J., Zarekookandeh, N., Hanson, O., Ekström, O., Asplund, O., Lamon, S., Alexander, S. E., Smith, C., Bauer, C., Woessner, M. N. & Levinger, I. & 16 others, , 24 Jun 2025, In: Cell Reports. 44, 6, 21 p., 115750.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Potential Role of Menstrual Fluid-Derived Small Extracellular Vesicle Proteins in Endometriosis Pathogenesiss
Gurung, S., Piskopos, J., Steele, J., Schittenhelm, R., Shah, A., Cousins, F. L., Tapmeier, T. T. & Gargett, C. E., Mar 2025, In: Journal of Extracellular Vesicles. 14, 3, 16 p., e70048.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Press/Media
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Faculty of Opinions recommendation
Payne, J., Cryle, M., Tailhades, J., Fulcher, A., Ellett, F., Irima, D., Kostoulias, X., Leung, R., Louch, S., Tran, A., Weber, S., Schittenhelm, R., Lieschke, G., Qin, C. H., Peleg, A. & Fu, T.
3/12/21
1 item of Media coverage
Press/Media: Article/Feature
Equipment
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Monash Proteomics & Metabolomics Platform (MPMP)
Schittenhelm, R. (Other) & Steer, D. (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility