Projects per year
Personal profile
Biography
Ralf studied Biochemistry at the University of Bayreuth, Germany, and received his PhD from the University of Zurich, Switzerland, in 2009 for his work on cell cycle regulation and the composition of centromeres and kinetochores in Drosophila melanogaster.
After his PhD, he joined the group of Prof. Dr. Ernst Hafen at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. In close collaboration with the group of Prof. Dr. Ruedi Aebersold, he identified and validated novel components of the insulin receptor / target of rapamycin (InR/TOR) pathway using mass spectrometric approaches in combination with biochemical assays.
In 2012, Ralf was awarded a Swiss National Foundation (SNF) Fellowship for Prospective Researchers and joined the group of Prof. Dr. Anthony Purcell at Monash University in Melbourne, Australia. During that time, he utilized high-resolution mass spectrometry to study the onset and progression of a variety of clinically relevant diseases known as spondyloarthropathies. Because of his work, Ralf was awarded with a SFGBM (Swiss Foundation for Grants in Biology and Medicine) Fellowship for Advanced Researchers in 2013.
In 2016, Ralf was appointed as the Director of the Monash Biomedical Proteomics Platform to provide mass spectrometric expertise to researchers and the broader community.
Network
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Investigating complement C5a receptor 2 as a therapeutic target for diabetic kidney disease
Tan, M., Coughlan, M., Ekinci, E., Woodruff, T. M. & Schittenhelm, R.
1/01/22 → 31/12/24
Project: Research
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Defining Chemotactic Signalling Networks to Identify New Anti-inflammatory Targets
Stone, M., Foster, S., Kufareva, I., Schittenhelm, R., Handel, T. M., Harper, B., Simpson, K. J. & Payne, R.
1/01/22 → 31/12/25
Project: Research
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Chromatin defects in histone mutated brain cancers: from basic mechanisms to novel therapeutic strategies
Wong, L., Collas, P., Jabado, N., Schittenhelm, R. & Rosenbluh, S.
1/01/22 → 31/12/25
Project: Research
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Defining the molecular switches that govern discrete cellular fates
Nguyen, L., Schittenhelm, R. & Kriegsheim, A. V.
21/12/21 → 20/12/24
Project: Research
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Identification of novel treatment targets for histone mutated cancers
Wong, L., Schittenhelm, R., Collas, P. & Jabado, N.
1/11/21 → 31/10/22
Project: Research
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Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus
Payne, J. A. E., Tailhades, J., Ellett, F., Kostoulias, X., Fulcher, A. J., Fu, T., Leung, R., Louch, S., Tran, A., Weber, S. A., Schittenhelm, R. B., Lieschke, G. J., Qin, C. H., Irima, D., Peleg, A. Y. & Cryle, M. J., Dec 2021, In: Nature Communications. 12, 1, 15 p., 6157.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model
Pham, L., Wright, D. K., O'Brien, W. T., Bain, J., Huang, C., Sun, M., Casillas-Espinosa, P. M., Shah, A. D., Schittenhelm, R. B., Sobey, C. G., Brady, R. D., O'Brien, T. J., Mychasiuk, R., Shultz, S. R. & McDonald, S. J., Jan 2021, In: Neurobiology of Disease. 148, 11 p., 105151.Research output: Contribution to journal › Article › Research › peer-review
Open Access7 Citations (Scopus) -
Component parts of bacteriophage virions accurately defined by a machine-learning approach built on evolutionary features
Thung, T. Y., White, M. E., Dai, W., Wilksch, J. J., Bamert, R. S., Rocker, A., Stubenrauch, C. J., Williams, D., Huang, C., Schittelhelm, R., Barr, J. J., Jameson, E., McGowan, S., Zhang, Y., Wang, J., Dunstan, R. A. & Lithgow, T., 27 May 2021, In: mSystems. 6, 3, 17 p., e00242-21.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
Turner, R. E., Harrison, P. F., Swaminathan, A., Kraupner-Taylor, C. A., Goldie, B. J., See, M., Peterson, A. L., Schittenhelm, R. B., Powell, D. R., Creek, D. J., Dichtl, B. & Beilharz, T. H., Jul 2021, In: eLife. 10, 35 p., e65331.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Identification of Koala (Phascolarctos cinereus) faecal cortisol metabolites using liquid chromatography‐mass spectrometry and enzyme immunoassays
Santamaria, F., Barlow, C. K., Schlagloth, R., Schittenhelm, R. B., Palme, R. & Henning, J., Jun 2021, In: Metabolites. 11, 6, 15 p., 393.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus)
Press / Media
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Faculty of Opinions recommendation
Jennifer Payne, Max Cryle, Julien Tailhades, Alex Fulcher, Felix Ellett, Daniel Irima, Xenia Kostoulias, Ryan Leung, Steph Louch, Amy Tran, Severin Weber, Ralf Schittenhelm, Graham Lieschke, Chengxue Helena Qin, Anton Peleg & Ting Fu
3/12/21
1 item of Media coverage
Press/Media: Article/Feature
Equipment
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Monash Proteomics & Metabolomics Facility
Ralf Schittenhelm (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility