Projects per year
Personal profile
Biography
Ralf studied Biochemistry at the University of Bayreuth, Germany, and received his PhD from the University of Zurich, Switzerland, in 2009 for his work on cell cycle regulation and the composition of centromeres and kinetochores in Drosophila melanogaster.
After his PhD, he joined the group of Prof. Dr. Ernst Hafen at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. In close collaboration with the group of Prof. Dr. Ruedi Aebersold, he identified and validated novel components of the insulin receptor / target of rapamycin (InR/TOR) pathway using mass spectrometric approaches in combination with biochemical assays.
In 2012, Ralf was awarded a Swiss National Foundation (SNF) Fellowship for Prospective Researchers and joined the group of Prof. Dr. Anthony Purcell at Monash University in Melbourne, Australia. During that time, he utilized high-resolution mass spectrometry to study the onset and progression of a variety of clinically relevant diseases known as spondyloarthropathies. Because of his work, Ralf was awarded with a SFGBM (Swiss Foundation for Grants in Biology and Medicine) Fellowship for Advanced Researchers in 2013.
In 2016, Ralf was appointed as the Director of the Monash Biomedical Proteomics Platform to provide mass spectrometric expertise to researchers and the broader community.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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Understanding the metabolic landscape in the human kidney in diabetes
Coughlan, M., Watt, M., Stroud, D. A., Ramm, G., Schittenhelm, R., Lazarou, M., McLean, C., Lawton, P. & Ekinci, E.
1/01/24 → 31/12/28
Project: Research
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Drug Target Identification Platform
Creek, D., Avery, V. M., Pitson, S. M., George, A. J., Olechnowicz, S., Baell, J., Schittenhelm, R., Li, J., Langmead, C., Stupple, P., Drinkwater, C., Flynn, B., Brouwer, K., Arndt, G. M. & Newman, S.
Department of Health and Aged Care (Australia)
30/06/23 → 6/12/28
Project: Research
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Preventing a nephron deficit in premature offspring
Bertram, J., Cullen-McEwen, L., Charlton, J., Simpson, S. J., Solon-Biet, S., Rose, A., Schittenhelm, R., Barlow, C., Combes, A., Tan, K., Johnstone, L., Wlodek, M. & Stanford, K. I.
1/01/23 → 31/12/26
Project: Research
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Uncovering novel mechanisms of treatment resistance in lethal colorectal cancers
Abud, H., Engel, R., McMurrick, P., Schittenhelm, R., Lum, C. D. R. & Archer, S.
1/01/23 → 31/12/25
Project: Research
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Characterization of the Germline Regulatory Landscape
Pocock, R., Cao, W., Fan, Q., Hutt, K., Gopal, S., Schittenhelm, R., Hobbs, R., Archer, S. & Coutts, S.
1/01/23 → 31/12/27
Project: Research
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Acute exercise-induced release of innate immune proteins via small extracellular vesicles changes with aerobic fitness and age
Chong, M. C., Shah, A. D., Schittenhelm, R. B., Silva, A., James, P. F., Wu, S. S. X. & Howitt, J., Mar 2024, In: Acta Physiologica. 240, 3, 16 p., e14095.Research output: Contribution to journal › Article › Research › peer-review
Open Access5 Citations (Scopus) -
A defined diet for pre-adult Drosophila melanogaster
Martelli, F., Quig, A., Mele, S., Lin, J., Fulton, T. L., Wansbrough, M., Barlow, C. K., Schittenhelm, R. B., Johnson, T. K. & Piper, M. D. W., Dec 2024, In: Scientific Reports. 14, 1, 9 p., 6974.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Analysis and visualization of quantitative proteomics data using FragPipe-Analyst
Hsiao, Y., Zhang, H., Li, G. X., Deng, Y., Yu, F., Kahrood, H. V., Steele, J. R., Schittenhelm, R. B. & Nesvizhskii, A. I., 11 Mar 2024, 33 p. bioRxiv.Research output: Other contribution › Research
Open Access -
Analysis and Visualization of Quantitative Proteomics Data Using FragPipe-Analyst
Hsiao, Y., Zhang, H., Li, G. X., Deng, Y., Yu, F., Valipour Kahrood, H., Steele, J. R., Schittenhelm, R. B. & Nesvizhskii, A. I., 4 Oct 2024, In: Journal of Proteome Research. 23, 10, p. 4303-4315 13 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
A Semiautomated Proteomics and Phosphoproteomics Protocol for the Identification of Novel Therapeutic Targets and Predictive Biomarkers in In Vivo Xenograft Models of Pediatric Cancers
Lim Kam Sian, T. CC., Sun, C., Cain, J. E., Steele, J. R., Hanchapola, I., Stoychev, S., Schittenhelm, R. B. & Faridi, P., 2024, Patient-Derived Xenografts: Methods and Protocols. Saad, M. I. (ed.). New York NY USA: Humana Press, p. 229-242 14 p. (Methods in Molecular Biology; vol. 2806).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
1 Citation (Scopus)
Press/Media
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Faculty of Opinions recommendation
Jennifer Payne, Max Cryle, Julien Tailhades, Alex Fulcher, Felix Ellett, Daniel Irima, Xenia Kostoulias, Ryan Leung, Steph Louch, Amy Tran, Severin Weber, Ralf Schittenhelm, Graham Lieschke, Chengxue Helena Qin, Anton Peleg & Ting Fu
3/12/21
1 item of Media coverage
Press/Media: Article/Feature
Equipment
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Monash Proteomics & Metabolomics Facility
Ralf Schittenhelm (Manager)
Faculty of Medicine Nursing and Health Sciences Research PlatformsFacility/equipment: Facility