Projects per year
Personal profile
Biography
Ralf studied Biochemistry at the University of Bayreuth, Germany, and received his PhD from the University of Zurich, Switzerland, in 2009 for his work on cell cycle regulation and the composition of centromeres and kinetochores in Drosophila melanogaster.
After his PhD, he joined the group of Prof. Dr. Ernst Hafen at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland. In close collaboration with the group of Prof. Dr. Ruedi Aebersold, he identified and validated novel components of the insulin receptor / target of rapamycin (InR/TOR) pathway using mass spectrometric approaches in combination with biochemical assays.
In 2012, Ralf was awarded a Swiss National Foundation (SNF) Fellowship for Prospective Researchers and joined the group of Prof. Dr. Anthony Purcell at Monash University in Melbourne, Australia. During that time, he utilized high-resolution mass spectrometry to study the onset and progression of a variety of clinically relevant diseases known as spondyloarthropathies. Because of his work, Ralf was awarded with a SFGBM (Swiss Foundation for Grants in Biology and Medicine) Fellowship for Advanced Researchers in 2013.
In 2016, Ralf was appointed as the Director of the Monash Biomedical Proteomics Platform to provide mass spectrometric expertise to researchers and the broader community.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2016 2020
Mechanisms of Ligand-Selective Signalling by Chemokine Receptors
Stone, M. J., Canals, M., Lane, R. & Schittenhelm, R. B.
1/01/18 → 31/12/20
Project: Research
Mapping pathways of human Z-antitrypsin turnover in transgenic zebrafish
Bird, P. I., Bryson-Richardson, R. J., Ramialison, M. S. M. & Schittenhelm, R. B.
1/07/16 → 30/06/18
Project: Research
Research Output 2005 2019
Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation
Ma, X., Zhang, L., Song, J., Nguyen, E., Lee, R. S., Rodgers, S. J., Li, F., Huang, C., Schittenhelm, R. B., Chan, H., Chheang, C., Wu, J., Brown, K. K., Mitchell, C. A., Simpson, K. J. & Daly, R. J., 17 Jan 2019, In : Nature Communications. 10, 1, 16 p., 296.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
Watt, M. J., Clark, A. K., Selth, L. A., Haynes, V. R., Lister, N., Rebello, R., Porter, L. H., Niranjan, B., Whitby, S. T., Lo, J., Huang, C., Schittenhelm, R. B., Anderson, K. E., Furic, L., Wijayaratne, P. R., Matzaris, M., Montgomery, M. K., Papargiris, M., Norden, S., Febbraio, M. & 4 others, 6 Feb 2019, In : Science Translational Medicine. 11, 478, 12 p., eaau5758.Research output: Contribution to journal › Article › Research › peer-review
AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning
Reichenbach, A., Stark, R., Mequinion, M., Denis, R. R. G., Goularte, J. F., Clarke, R. E., Lockie, S. H., Lemus, M. B., Kowalski, G. M., Bruce, C. R., Huang, C., Schittenhelm, R. B., Mynatt, R. L., Oldfield, B. J., Watt, M. J., Luquet, S. & Andrews, Z. B., 13 Feb 2018, In : Cell Reports. 22, 7, p. 1745-1759 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
Koch, B., Barugahare, A. A., Lo, T. L., Huang, C., Schittenhelm, R. B., Powell, D. R., Beilharz, T. H. & Traven, A., 20 Nov 2018, In : Cell Reports. 25, 8, p. 2244-2258 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Biodosimetric transcriptional and proteomic changes are conserved in irradiated human tissue
Keam, S. P., Gulati, T., Gamell, C., Caramia, F., Arnau, G. M., Huang, C., Schittenhelm, R. B., Kleifeld, O., Neeson, P. J., Williams, S. G. & Haupt, Y., 30 May 2018, (Accepted/In press) In : Radiation and Environmental Biophysics. 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File