Projects per year
Personal profile
Biography
Dr. Rakesh Naidu is a Professor in Biomedical Science at the Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia. He was a lecturer in International Medical University and Department of Molecular Medicine, Faculty of Medicine, University of Malaya prior to his appointment at Monash University. He is involved in the teaching of biochemistry, genetics, and cancer. His current research focuses on the molecular biology of cancer, cancer therapeutics, and cancer venomics. He has been successful in securing several internal and external research grants in the research areas of molecular oncology and cancer therapeutics. He has published peer-reviewed research papers in several international and national journals and book chapters in cancer. He has supervised and currently supervising several graduate students including PhD and Masters over the years.
Research interests
Dr Rakesh Naidu is actively involved in cancer research. One of the research interests is to understand the molecular alterations that lead to cancer development with particular focus on breast, prostate and colon cancers. Genomics and proteomics analysis were performed on human cancer samples to determine and identify several genetics alteration that could potentially be used as biomarkers and to understand mechanisms underlying cancer development. Some of the genetic alterations noted were distinct than that reported by other investigators perhaps of different demographics and ethnic population. Currently, his research group focuses on identification and understanding the underlying molecular mechanisms of synthetic compounds and analogues derived from natural compounds as well as natural components from venoms that contribute to anti-cancer activities in human cancer cells such as cervical, prostate, colon, breast and lung. Several ‘omics’ platform technologies such as transcriptomics and proteomics are used to identify specific target mRNAs, miRNAs and proteins as well as relevant biological pathways modulated by these potential anticancer compounds. High-density microarrays, sequencing and mass spectrometry are used to achieve these outcomes which contribute to the understanding of targeted anti-cancer therapy by these compounds that may lead to future development of novel anti-cancer drugs.
Monash teaching commitment
- Student Project Cases
- Problem Based Learning
- Biochemistry
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Molecular Oncology, MSc, Universiti Malaya (University of Malaya)
Molecular Oncology, PhD, Universiti Malaya (University of Malaya)
BSc(Ed), Universiti Sains Malaysia (University of Science Malaysia)
Research area keywords
- Biomedical Science
- Cancer Therapeutics
- Molecular Oncology
- Genomics
- Transcriptomics
- Proteomics
- Cancer Venomics
- Cancer Biology
Collaborations and top research areas from the last five years
Projects
- 7 Finished
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Induction of Apoptosis and Identification of Molecular Pathways and Molecular Targets in Human Lung Cancer Cells Treated by a Selected Synthetic Diarylpentanoid
Naidu, R., Abas, F., Kia Fatt, Q. & Othman, I.
1/11/20 → 31/10/22
Project: Research
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Investigating the underlying cause of downregulation of semaphorin 5A and the loss of its tumor suppressor function in human glioblastomas
Lee, A. Y. W. & Naidu, R.
1/09/19 → 30/11/22
Project: Research
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Anticancer Mechanism of Flavonoids on High-Grade Adult-Type Diffuse Gliomas
Wong, S. C., Kamarudin, M. N. A. & Naidu, R., Feb 2023, In: Nutrients. 15, 4, 25 p., 797.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile4 Citations (Scopus) -
Editorial: Curcuminoids: their pleiotropism against hallmarks of cancers
Pouliquen, D. L., Gall Trošelj, K., Anto, R. J. & Naidu, R., 18 Aug 2023, In: Frontiers in Pharmacology. 14, 3 p., 1266793.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access -
Environmental Enrichment and Metformin Improve Metabolic Functions, Hippocampal Neuron Survival, and Hippocampal-Dependent Memory in High-Fat/High-Sucrose Diet-Induced Type 2 Diabetic Rats
Ismail, T. R., Yap, C. G., Naidu, R. & Pamidi, N., Mar 2023, In: Biology. 12, 3, 22 p., 480.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile -
Flavonoids as receptor tyrosine kinase inhibitors in lung cancer
Sudhesh Dev, S., Farghadani, R., Zainal Abidin, S. A., Othman, I. & Naidu, R., Nov 2023, In: Journal of Functional Foods. 110, 22 p., 105845.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile -
KISSPEPTIN INDUCES MESENCHYMAL TRANSITION (MES) VIA PROTEOMIC REGULATION OF MES-TRANSCRIPTION FACTORS AND CYTOSKELETAL REMODELLING PROTEINS FOR THE PROMOTION OF CELL INVASION IN KISS1R-EXPRESSING GLIOBLASTOMA CELLS
Chow, M. Y., Zainal Abidin, S. A., Eswaran, J., Naidu, R. & Kamarudin, M. N. A., Oct 2023, In: IBRO Neuroscience Reports. 15, Supplement 1, p. S546 1 p.Research output: Contribution to journal › Meeting Abstract › peer-review
Open AccessFile
Activities
- 4 Contribution to conference
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The 35th Annual Lorne Cancer Conference 2023
MNA Kamarudin (Speaker), Rakesh Naidu (Speaker), Min Yee Chow (Speaker) & Syafiq Asnawi (Speaker)
9 Feb 2023 → 11 Feb 2023Activity: Participating in or organising an event types › Contribution to conference
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The 35th Annual Lorne Cancer Conference 2023
Isra Saif Eldin Eisa Sati (Speaker), MNA Kamarudin (Organiser), Rakesh Naidu (Speaker) & Tomoko Soga (Speaker)
9 Feb 2023 → 11 Feb 2023Activity: Participating in or organising an event types › Contribution to conference
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IBRO World Congress of Neuroscience 2023
Min Yee Chow (Speaker), MNA Kamarudin (Speaker), Rakesh Naidu (Speaker) & Syafiq Asnawi (Speaker)
9 Sept 2023 → 13 Sept 2023Activity: Participating in or organising an event types › Contribution to conference
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The 35th Annual Lorne Cancer Conference 2023
Prakrithi Narayanan (Speaker), MNA Kamarudin (Speaker), Rakesh Naidu (Speaker) & Syafiq Asnawi (Speaker)
9 Feb 2023 → 11 Feb 2023Activity: Participating in or organising an event types › Contribution to conference