Pradeep Nathan

Professor

20012018
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Personal profile

Biography

Professor Pradeep Nathan is an Adjunct Professor in the School of Psychology and Psychiatry.

He is a clinical pharmacologist with research interests in the neuropharmacology and neural substrates of cognition and emotion and psychiatric and neurological endophenotypes. He uses cognitive, functional and molecular neuroimaging techniques (i.e. fMRI, Electrophysiology, PET) to understand where and how neuropharmacological agents modulate cognitive and emotional processes and associated neural networks. He is also interested in the application of these approaches to CNS drug discovery through development of functional biomarkers which might aid in the development of more refined and targeted treatment approaches for cognitive and emotional dysfunction in psychiatric and neurological disorders.

He is Senior Director, Neuroscience Discovery Medicine at UCB Pharma where he is involved in research and development of small molecules and antibodies for cognition in Schizophrenia, Epilepsy, Alzheimer's disease and Parkinson's disease.

Keywords

  • Alzheimer's disease
  • Drug discovery
  • Parkinson's disease
  • brain imaging
  • cognition
  • drug development
  • neuropharmacology
  • schizophrenia

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Projects 2005 2011

Research Output 2001 2018

The effects of glycine on auditory mismatch negativity in schizophrenia

Greenwood, L-M., Leung, S., Michie, P. T., Green, A., Nathan, P. J., Fitzgerald, P., Johnston, P., Solowij, N., Kulkarni, J. & Croft, R. J., Jan 2018, In : Schizophrenia Research. 191, p. 61-69 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI)

Nathan, P. J., Lim, Y. Y., Abbott, R., Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Bartres-Faz, D., Didic, M., Farotti, L., Parnetti, L., Salvadori, N., Müller, B. W., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J. L. & 15 othersNobili, F., Pariente, J., Payoux, P., Ranjeva, J. P., Rolandi, E., Rossini, P. M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P. J., Wiltfang, J., Richardson, J. C., Bordet, R., Blin, O. J. & Frisoni, G. B., 1 May 2017, In : Neurobiology of Aging. 53, p. 1-10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Evidence for a differential contribution of early perceptual and late cognitive processes during encoding to episodic memory impairment in schizophrenia

Green, A. E., Fitzgerald, P. B., Johnston, P. J., Nathan, P. J., Kulkarni, J. & Croft, R. J., 4 Jul 2017, In : World Journal of Biological Psychiatry. 18, 5, p. 369-381 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Assessment of cognitive safety in clinical drug development

Roiser, J. P., Nathan, P. J., Mander, A. P., Adusei, G., Zavitz, K. H. & Blackwell, A. D., 1 Mar 2016, In : Drug Discovery Today. 21, 3, p. 445-453 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Impact of 5-HTTLPR on SSRI serotonin transporter blockade during emotion regulation: A preliminary fMRI study

Outhred, T., Das, P., Dobson-Stone, C., Felmingham, K. L., Bryant, R. A., Nathan, P. J., Malhi, G. S. & Kemp, A. H., 15 May 2016, In : Journal of Affective Disorders. 196, p. 11-19 9 p.

Research output: Contribution to journalArticleResearchpeer-review