Projects per year
Personal profile
Biography
Dr Pouya Faridi is the head of the Translational Antigen Discovery Laboratory at the School of Clinical Sciences, Monash University. After completing his pharmacy doctorate and PhD at the Shiraz University of Medical Sciences, Iran, he joined Prof Ruedi Aebersold’s laboratory at Institute for Molecular Systems Biology at the ETH Zurich, Switzerland. In 2016, he moved to Australia and joined Prof Tony Purcell’s lab at Biomedicine Discovery Institute, Monash University. In 2021, he established his own laboratory at the Department of Medicine, Monash University.
Dr Faridi has developed several mass-spectrometry and proteomics technologies to identify and quantify peptides, proteins, and metabolites. He has applied these technologies to identify and validate actionable targets for cancer immunotherapy. Some of the peptides he identified are currently used for cancer vaccination clinical studies. In addition to his research lab, Dr Faridi is the co-director of the Monash Clinical Proteomics Facility.
Dr Faridi’s research excellence is shown by the mid-career fellowship from the Victorian Cancer Agency for the development of precision vaccines for devastating paediatric brain tumours. He has several patents in the antigen discovery field, and his research has been published in prestigious journals, including Cell, Science Immunology, Nature Communications and Cancer Immunology Research. Faridi lab is supported by NHMRC, Cancer Australia, Australian Melanoma Research Foundation and Isabella & Marcus Foundation.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Honorary Research Associate, Hudson Institute of Medical Research
12 Aug 2021 → …
Collaborations and top research areas from the last five years
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Determination of “actionable vaccine targets” for breast cancer immunotherapy
Faridi, P., Dolcetti, R., Purcell, A., Mazzieri, R. & Southey, M.
1/01/23 → 31/12/26
Project: Research
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Targeted Regulatory T Cells to Treat SLE
Ooi, J., Faridi, P. & Morand, E.
United States Department of Defense (DOD)
1/09/22 → 31/08/25
Project: Research
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Pioneering novel therapeutic strategies to enhance an anti-tumour immune response in Neuroblastoma
Vittorio, O., Saletta, F., Murray, J., Mayoh, C. & Faridi, P.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/22 → 31/12/24
Project: Research
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Dominant classes of tumour specific antigens in Melanoma
Purcell, A., Faridi, P., Shackleton, M., Linette, G. & Behren, A.
1/01/22 → 31/12/24
Project: Research
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The development of precision vaccines for devastating paediatric brain tumours
Faridi, P., Purcell, A., Nazarian, J., Hansford, J. R., Jabado, N., Linette, G., Behren, A., Cain, J. & Ludlow, L.
19/03/21 → 18/03/25
Project: Research
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Benchmarking Bioinformatics Pipelines in Data-Independent Acquisition Mass Spectrometry for Immunopeptidomics
Shahbazy, M., Ramarathinam, S. H., Illing, P. T., Jappe, E. C., Faridi, P., Croft, N. P. & Purcell, A. W., Apr 2023, In: Molecular and Cellular Proteomics. 22, 4, 14 p., 100515.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Engineering Cell Lines for Specific Human Leukocyte Antigen Presentation
Jin, D., Loh, K. L., Shamekhi, T., Ting, Y. T., Lim Kam Sian, T. C. C., Roest, J., Ooi, J. D., Vivian, J. P. & Faridi, P., 25 Jun 2023, Infammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). 2nd ed. New York NY USA: Humana Press, p. 351-369 19 p. (Methods in Molecular Biology; vol. 2691).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
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Immunolyser: A web-based computational pipeline for analysing and mining immunopeptidomic data
Munday, P. R., Fehring, J., Revote, J., Pandey, K., Shahbazy, M., Scull, K. E., Ramarathinam, S. H., Faridi, P., Croft, N. P., Braun, A., Li, C. & Purcell, A. W., Jan 2023, In: Computational and Structural Biotechnology Journal. 21, p. 1678-1687 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
SAPrIm, a semi-automated protocol for mid-throughput immunopeptidomics
Lim Kam Sian, T. C. C., Goncalves, G., Steele, J. R., Shamekhi, T., Bramberger, L., Jin, D., Shahbazy, M., Purcell, A. W., Ramarathinam, S., Stoychev, S. & Faridi, P., 2 Jun 2023, In: Frontiers in Immunology. 14, 10 p., 1107576.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF
Dannappel, M. V., Zhu, D., Sun, X., Chua, H. K., Poppelaars, M., Suehiro, M., Khadka, S., Lim Kam Sian, T. C. C., Sooraj, D., Loi, M., Gao, H., Croagh, D., Daly, R. J., Faridi, P., Boyer, T. G. & Firestein, R., 17 Oct 2022, In: The Journal of Clinical Investigation. 132, 20, 15 p., e158593.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)
Prizes
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Australasian Proteomics Society Early Career Researcher Award
Faridi, Pouya (Recipient), Feb 2019
Prize: Prize (including medals and awards)
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Australasian Proteomics Society Early Career Researcher Travel Grant
Faridi, Pouya (Recipient), 2017
Prize: Prize (including medals and awards)
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Australian Melanoma Research Foundation Early Career Researcher award
Faridi, Pouya (Recipient), 2021
Prize: National/international honour
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European Molecular Biology Organization (EMBO) Postdoctoral Travel Grant
Faridi, Pouya (Recipient), May 2019
Prize: Prize (including medals and awards)
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Monash University BDI Awards for Outstanding International Collaboration
Faridi, Pouya (Recipient), 6 Dec 2019
Prize: Prize (including medals and awards)
Activities
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Cancers (Journal)
Pouya Faridi (Guest editor)
2022 → 2023Activity: Publication peer-review and editorial work types › Editorial responsibility
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The Human Immunopeptidome Project summer school
Pouya Faridi (Organiser)
2022 → …Activity: Participating in or organising an event types › Contribution to workshop, seminar, course
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Trends in Microbiology (Journal)
Pouya Faridi (Peer reviewer)
2021 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Nature Biotechnology (Journal)
Pouya Faridi (Peer reviewer)
2021 → …Activity: Publication peer-review and editorial work types › Editorial responsibility
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Frontiers in Immunology (Journal)
Pouya Faridi (Editorial board member)
2021 → …Activity: Publication peer-review and editorial work types › Editorial responsibility