Research output per year
Research output per year
Personal profile
Biography
Dr Polly Yap obtained her BSc (Hons) Medical Biotechnology and MSc (By Research) Medical Sciences from International Medical University, Malaysia. She obtained her PhD in Medical Microbiology from University of Malaya. Her PhD thesis involved studying the temporal dynamics of gut microbiome and metabolome of preterm neonates. Her research has also targeted to elucidate the resistance mechanism of intestinal carriage of multidrug resistant bacteria. She is also interested in improving methods and knowledge of the sources and transmission data of antimicrobial resistance between humans, animals from food, and the environment.
Research interests
Dr Polly Yap started her research career with her master project heavily involved in elucidating the mechanisms of antibiotic resistance reversal potential of essential oils against the clinically important and multidrug resistant bacteria. Since then, she hopes her work will contribute in reducing and combating the burden of antimicrobial resistance.
Her PhD training has enabled her to gain technical skills in 16S data processing, whole genome sequencing, and nuclear magnetic resonance spectroscopy. She is also experienced in troubleshooting and library sample preparation on the Next-Generation Sequencing (NGS) platforms.
Dr Polly’s main research interests include analysis of sources and transmission pathways of multidrug resistant bacteria in a One Health perspective, using techniques such as genomics, multivariate analyses, and machine learning. She is also interested to investigate the human health consequences of intestinal carriage of multidrug resistant bacteria. She hopes to use her work to bring awareness to the wider population that human health is closely related to the animal, environmental and public health.
Research Interest and Area of Expertise
- Medical Microbiology – NGS of clinically important pathogens; Antimicrobial Resistance; Molecular Genomics; Molecular Epidemiology
- Urban and Rural Health – Gut microbiome; One Health; infectious diseases
- Omics Technologies – Metagenomics and Metabolomics
- Natural products – Drug discovery; Reversal of antimicrobial resistance and mechanism
Community service
Dr Polly is also passionate about science communication. She is a Lesson Leader of One Health Lessons, taking on a mission to get every child on the planet caring about One Health.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medical Microbiology, PhD, Universiti Malaya (University of Malaya)
Research area keywords
- Microbial genomics
- Infectious disease genomics
- Metagenomics
- Metabolomics
- Gut microbiome
- Klebsiella pneumoniae
- Multidrug-Resistant Pathogens
- Antimicrobial Resistance
- One Health
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Anti- and pro-oxidant properties of essential oils against antimicrobial resistance
Kong, A. S-Y., Maran, S., Yap, P. S-X., Lim, S-H. E., Yang, S-K., Cheng, W-H., Tan, Y-H. & Lai, K-S., Sep 2022, In: Antioxidants. 11, 9, 12 p., 1819.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile1 Citation (Scopus) -
Host–bacterial interactions: Outcomes of antimicrobial peptide applications
Alkatheri, A. H., Yap, P. S-X., Abushelaibi, A., Lai, K-S., Cheng, W-H. & Lim, S-H. E., Jul 2022, In: Membranes. 12, 7, 21 p., 715.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile -
MgrB mutations and altered cell permeability in colistin resistance in Klebsiella pneumoniae
Yap, P. S-X., Cheng, W-H., Chang, S-K., Lim, S-H. E. & Lai, K-S., 1 Oct 2022, In: Cells. 11, 19, 11 p., 2995.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile1 Citation (Scopus) -
Overview of the distribution of Burkholderia pseudomallei sequence types and the Emergence of sequence type 1342 in Malaysia
Teh, C. S. J., Yap, P. S. X., Zulkefli, N. J., Subramaniam, P., Sit, P. S., Kong, Z. X., Chong, C. W., Vellasamy, K. M., Mariappan, V., Ponnampalavanar, S. & Vadivelu, J., Mar 2022, In: Transboundary and Emerging Diseases. 69, 2, p. 477-484 8 p.Research output: Contribution to journal › Article › Research › peer-review
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The potential use of essential oils as natural biocides against plant pathogens
Aljaafari, M. N., Yap, P. S. X., Seboussi, R., Lai, K. S. & Lim, S. H. E., 2022, Pesticides in the Natural Environment: Sources, Health Risks, and Remediation. Singh, P., Singh, S. & Sillanpää, M. (eds.). 1st ed. Amsterdam Netherlands: Elsevier, p. 317-328 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Prizes
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Best Oral Presenter - 2nd runner up
Yap, Polly (Recipient), 2022
Prize: Prize (including medals and awards)
Activities
- 2 Peer review responsibility
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Scientific Reports (Journal)
Polly Yap (Peer reviewer)
2022Activity: Publication peer-review and editorial work types › Peer review responsibility
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PLoS ONE (Journal)
Polly Yap (Peer reviewer)
2022Activity: Publication peer-review and editorial work types › Peer review responsibility