Projects per year
Personal profile
Biography
Dr Poh-Yi Gan is an NHMRC Research Fellow and Head of the Targeted Nanomedicines Group at the Centre for Inflammatory Diseases, Monash University. Dr Gan completed her PhD in 2014 at Monash University under the supervision of Prof Stephen Holdsworth to study the role of CD4+ T cell subsets in autoimmune kidney disease. Dr Gan is funded by NHMRC, Department of Health Medical Research Future Fund, Heart Foundation and School of Clinical Sciences at Monash Health.
Dr Gan’s research program focuses on discovering injurious cellular effector mediators that can be specifically targeted using biologicals and developing novel therapeutics capable of inducing antigen specific tolerance in autoimmune kidney disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Autoimmunity
- Immunotherapy
- Kidney Disease
- Vasculitis
- Tolerance
- MPO-ANCA
- Biologicals
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
A novel pharmaco-genetic treatment for auto-immune kidney disease
Logan, G. (Primary Chief Investigator (PCI)), O'Sullivan, K. (Chief Investigator (CI)), Lisowski, L. (Associate Investigator (AI)), Thomas, B. (Associate Investigator (AI)), Alexander, I. (Associate Investigator (AI)) & Gan, P. Y. (Associate Investigator (AI))
1/01/23 → 31/12/25
Project: Research
-
Boosting regulatory T cells with kidney-targeted nanoparticles to treat diabetic kidney disease
Coughlan, M. (Primary Chief Investigator (PCI)), Ooi, J. (Chief Investigator (CI)), Tan, M. (Chief Investigator (CI)) & Gan, P. Y. (Chief Investigator (CI))
1/01/23 → 30/12/23
Project: Research
-
Human Amniotic Epithelial Stem Cells as Novel Treatment for Autoimmune Vasculitis
Holdsworth, S. (Primary Chief Investigator (PCI)), Odobasic, D. (Chief Investigator (CI)), Gan, P. Y. (Chief Investigator (CI)) & O'Sullivan, K. (Chief Investigator (CI))
1/06/20 → 30/11/22
Project: Research
-
Immunomodulatory Mast Cells as Therapeutic Agents in Chronic Autoimmune and Acute Inflammatory Kidney Disease
Gan, P. Y. (Primary Chief Investigator (PCI)) & Holdsworth, S. (Chief Investigator (CI))
1/01/19 → 31/12/22
Project: Research
-
Stabilizing mast cells to prevent cardiac ischaemia-reperfusion injury
Holdsworth, S. (Primary Chief Investigator (PCI)), Smith, J. (Chief Investigator (CI)), Polkinghorne, K. (Chief Investigator (CI)) & Gan, P. Y. (Chief Investigator (CI))
National Heart Foundation of Australia
1/07/21 → 1/08/24
Project: Research
-
Engineered antigen-specific T regulatory cells suppress autoreactivity to the anti–glomerular basement membrane disease antigen
Eggenhuizen, P. J., Ng, B. H., Lo, C., Chang, J., Snelgrove, S. L., Cheong, R. M. Y., Shen, C., Lim, S., Zhong, Y., Gan, P. Y. & Ooi, J. D., Apr 2025, In: Kidney International. 107, 4, p. 751-756 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Corrigendum: Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT) (Frontiers in Neuroscience, (2023), 17, (1153231), 10.3389/fnins.2023.1153231)
Phan, T. G., Lim, R., Krause, M., Chan, S. T., McDonald, H., Gan, P. Y., Zhang, S. R., Barreto Arce, L. J., Vuong, J., Thirugnanachandran, T., Clissold, B., Ly, J., Singhal, S., Hervet, M. V., Kim, H. A., Drummond, G. R., Wallace, E. M., Ma, H. & Sobey, C. G., 2023, In: Frontiers in Neuroscience. 17, 1 p., 1237920.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Phase I trial outcome of amnion cell therapy in patients with ischemic stroke (I-ACT)
Phan, T. G., Lim, R., Krause, M., Chan, S. T., McDonald, H., Gan, P. Y., Zhang, S. R., Barreto Arce, L. J., Vuong, J., Thirugnanachandran, T., Clissold, B., Ly, J., Singhal, S., Hervet, M. V., Kim, H. A., Drummond, G. R., Wallace, E. M., Ma, H. & Sobey, C. G., 2023, In: Frontiers in Neuroscience. 17, 10 p., 1153231.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis
Ford, S. L., O’Sullivan, K. M., Kitching, A. R., Holdsworth, S. R., Gan, P. Y. & Summers, S. A., Jan 2023, In: International Journal of Molecular Sciences. 24, 2, 17 p., 1339.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Heterologous Immunity Between SARS-CoV-2 and Pathogenic Bacteria
Eggenhuizen, P. J., Ng, B. H., Chang, J., Cheong, R. M. Y., Yellapragada, A., Wong, W. Y., Ting, Y. T., Monk, J. A., Gan, P.-Y., Holdsworth, S. R. & Ooi, J. D., 27 Jan 2022, In: Frontiers in Immunology. 13, 18 p., 821595.Research output: Contribution to journal › Article › Research › peer-review
Open Access19 Citations (Scopus)
Prizes
-
Australian and New Zealand Society of Nephrology Best Basic Science (Winner)
Gan, P. Y. (Recipient), 2014
Prize: Prize (including medals and awards)
-
Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, P. Y. (Recipient), 2013
Prize: Prize (including medals and awards)
-
Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, P. Y. (Recipient), 2015
Prize: Prize (including medals and awards)
-
Australian and New Zealand Society of Nephrology Best Basic Science Award (First Runner Up)
Gan, P. Y. (Recipient), 2017
Prize: Prize (including medals and awards)
-
Australian and New Zealand Society of Nephrology Young Investigator Award (Winner)
Gan, P. Y. (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
- 2 Hosting an academic or industry visitor
-
Kei Nagai
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2016 → 2018Activity: Hosting a visitor types › Hosting an academic or industry visitor
-
Takeshi Fujita
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2014 → 2016Activity: Hosting a visitor types › Hosting an academic or industry visitor