Projects per year
Personal profile
Biography
Dr Poh-Yi Gan is an NHMRC Research Fellow and Head of the Translational Kidney Therapies Group at the Centre for Inflammatory Diseases at Monash University. She completed her PhD in 2014 at Monash University under the supervision of Prof Stephen Holdsworth to study the role of CD4+ T cell subsets in autoimmune kidney disease. Dr Gan is funded by NHMRC, Department of Health Medical Research Future Fund, Heart Foundation and School of Clinical Sciences at Monash Health.
Dr Gan’s research program focuses on discovering injurious cellular effector mediators that can be specifically targeted using biologicals and developing novel therapeutics capable of inducing antigen specific tolerance in autoimmune kidney disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Autoimmunity
- Immunotherapy
- Kidney Disease
- Vasculitis
- Tolerance
- MPO-ANCA
- Biologicals
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Boosting regulatory T cells with kidney-targeted nanoparticles to treat diabetic kidney disease
Coughlan, M., Ooi, J., Tan, M. & Gan, P. Y.
1/01/23 → 30/12/23
Project: Research
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A novel pharmaco-genetic treatment for auto-immune kidney disease
Logan, G., O'Sullivan, K., Lisowski, L., Thomas, B., Alexander, I. & Gan, P. Y.
1/01/23 → 31/01/25
Project: Research
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Stabilizing mast cells to prevent cardiac ischaemia-reperfusion injury
Holdsworth, S., Smith, J., Polkinghorne, K. & Gan, P. Y.
1/07/21 → 30/06/24
Project: Research
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Human Amniotic Epithelial Stem Cells as Novel Treatment for Autoimmune Vasculitis
Holdsworth, S., Odobasic, D., Gan, P. Y. & O'Sullivan, K.
1/06/20 → 30/11/22
Project: Research
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Immunomodulatory Mast Cells as Therapeutic Agents in Chronic Autoimmune and Acute Inflammatory Kidney Disease
Gan, P. Y. & Holdsworth, S.
1/01/19 → 31/12/22
Project: Research
Research output
- 41 Article
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Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis
Ford, S. L., O’Sullivan, K. M., Kitching, A. R., Holdsworth, S. R., Gan, P. Y. & Summers, S. A., Jan 2023, In: International Journal of Molecular Sciences. 24, 2, 17 p., 1339.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Heterologous Immunity Between SARS-CoV-2 and Pathogenic Bacteria
Eggenhuizen, P. J., Ng, B. H., Chang, J., Cheong, R. M. Y., Yellapragada, A., Wong, W. Y., Ting, Y. T., Monk, J. A., Gan, P-Y., Holdsworth, S. R. & Ooi, J. D., 27 Jan 2022, In: Frontiers in Immunology. 13, 18 p., 821595.Research output: Contribution to journal › Article › Research › peer-review
Open Access8 Citations (Scopus) -
Anti-CD20 mAb-Induced B Cell Apoptosis Generates T Cell Regulation of Experimental Myeloperoxidase ANCA-Associated Vasculitis
Gan, P. Y., Dick, J., O'Sullivan, K. M., Oudin, V., Cao Le, A., Koo Yuk Cheong, D., Shim, R., Alikhan, M., Kitching, A. R., Ooi, J. D. & Holdsworth, S. R., 3 May 2021, In: Journal of the American Society of Nephrology. 32, 5, p. 1071-1083 13 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity
Eggenhuizen, P. J., Ng, B. H., Chang, J., Fell, A. L., Cheong, R. M. Y., Wong, W. Y., Gan, P-Y., Holdsworth, S. R. & Ooi, J. D., 5 Aug 2021, In: Frontiers in Immunology. 12, 12 p., 692729.Research output: Contribution to journal › Article › Research › peer-review
Open Access22 Citations (Scopus) -
Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
O'Sullivan, K. M., Creed, S. J., Gan, P. Y. & Holdsworth, S. R., 18 Jun 2020, In: Journal of Visualized Experiments. 2020, 160, 19 p., e61180.Research output: Contribution to journal › Article › Other › peer-review
1 Citation (Scopus)
Prizes
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Australian and New Zealand Society of Nephrology Best Basic Science (Winner)
Gan, Poh Yi (Recipient), 2014
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, Poh Yi (Recipient), 2015
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, Poh Yi (Recipient), 2013
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (First Runner Up)
Gan, Poh Yi (Recipient), 2017
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Young Investigator Award (Winner)
Gan, Poh Yi (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
- 2 Hosting an academic or industry visitor
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Kei Nagai
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2016 → 2018Activity: Hosting a visitor types › Hosting an academic or industry visitor
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Takeshi Fujita
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2014 → 2016Activity: Hosting a visitor types › Hosting an academic or industry visitor