Projects per year
Personal profile
Biography
Dr Poh-Yi Gan is an NHMRC Research Fellow and Head of the Translational Kidney Therapies Group at the Centre for Inflammatory Diseases at Monash University. She completed her PhD in 2014 at Monash University under the supervision of Prof Stephen Holdsworth to study the role of CD4+ T cell subsets in autoimmune kidney disease. Dr Gan is funded by NHMRC, Department of Health Medical Research Future Fund, Heart Foundation and School of Clinical Sciences at Monash Health.
Dr Gan’s research program focuses on discovering injurious cellular effector mediators that can be specifically targeted using biologicals and developing novel therapeutics capable of inducing antigen specific tolerance in autoimmune kidney disease.
Research area keywords
- Autoimmunity
- Immunotherapy
- Kidney Disease
- Vasculitis
- Tolerance
- MPO-ANCA
- Biologicals
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 3 Active
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Stabilizing mast cells to prevent cardiac ischaemia-reperfusion injury
Holdsworth, S., Smith, J., Polkinghorne, K. & Gan, P. Y.
1/07/21 → 30/06/23
Project: Research
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Human Amniotic Epithelial Stem Cells as Novel Treatment for Autoimmune Vasculitis
Holdsworth, S., Odobasic, D., Gan, P. Y. & O'Sullivan, K.
1/06/20 → 30/11/22
Project: Research
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Immunomodulatory Mast Cells as Therapeutic Agents in Chronic Autoimmune and Acute Inflammatory Kidney Disease
Gan, P. Y. & Holdsworth, S.
1/01/19 → 31/12/22
Project: Research
Research output
- 39 Article
-
Anti-CD20 mAb-Induced B Cell Apoptosis Generates T Cell Regulation of Experimental Myeloperoxidase ANCA-Associated Vasculitis
Gan, P. Y., Dick, J., O'Sullivan, K. M., Oudin, V., Cao Le, A., Koo Yuk Cheong, D., Shim, R., Alikhan, M., Kitching, A. R., Ooi, J. D. & Holdsworth, S. R., 3 May 2021, In: Journal of the American Society of Nephrology. 32, 5, p. 1071-1083 13 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity
Eggenhuizen, P. J., Ng, B. H., Chang, J., Fell, A. L., Cheong, R. M. Y., Wong, W. Y., Gan, P-Y., Holdsworth, S. R. & Ooi, J. D., 5 Aug 2021, In: Frontiers in Immunology. 12, 12 p., 692729.Research output: Contribution to journal › Article › Research › peer-review
Open Access10 Citations (Scopus) -
Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
O'Sullivan, K. M., Creed, S. J., Gan, P. Y. & Holdsworth, S. R., 18 Jun 2020, In: Journal of Visualized Experiments. 2020, 160, 19 p., e61180.Research output: Contribution to journal › Article › Other › peer-review
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A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity
Ooi, J. D., Jiang, J-H., Eggenhuizen, P. J., Chua, L. L., van Timmeren, M., Loh, K. L., O’Sullivan, K. M., Gan, P. Y., Zhong, Y., Tsyganov, K., Shochet, L. R., Ryan, J., Stegeman, C. A., Fugger, L., Reid, H. H., Rossjohn, J., Heeringa, P., Holdsworth, S. R., Peleg, A. Y. & Kitching, A. R., 29 Jul 2019, In: Nature Communications. 10, 1, 14 p., 3392.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile21 Citations (Scopus) -
Apoptotic Cell-Induced, Antigen-Specific Immunoregulation to Treat Experimental Antimyeloperoxidase GN
Gan, P. Y., Godfrey, A. S., Ooi, J. D., O'Sullivan, K. M., Oudin, V., Kitching, A. R. & Holdsworth, S. R., 1 Aug 2019, In: Journal of the American Society of Nephrology. 30, 8, p. 1365-1374 10 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus)
Prizes
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Australian and New Zealand Society of Nephrology Best Basic Science (Winner)
Gan, Poh Yi (Recipient), 2014
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, Poh Yi (Recipient), 2015
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (Finalist)
Gan, Poh Yi (Recipient), 2013
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Best Basic Science Award (First Runner Up)
Gan, Poh Yi (Recipient), 2017
Prize: Prize (including medals and awards)
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Australian and New Zealand Society of Nephrology Young Investigator Award (Winner)
Gan, Poh Yi (Recipient), 2011
Prize: Prize (including medals and awards)
Activities
- 2 Hosting an academic or industry visitor
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Kei Nagai
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2016 → 2018Activity: Hosting a visitor types › Hosting an academic or industry visitor
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Takeshi Fujita
Poh Yi Gan (Host) & Stephen Holdsworth (Host)
2014 → 2016Activity: Hosting a visitor types › Hosting an academic or industry visitor