Piero Perucca

Assoc Professor

Accepting PhD Students

20062022
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Research Output 2006 2019

2019

Electrophysiological biomarkers of epileptogenicity after traumatic brain injury

Perucca, P., Smith, G., Santana-Gomez, C., Bragin, A. & Staba, R., Mar 2019, In : Neurobiology of Disease. 123, p. 69-74 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis

Santana-Gomez, C., Andrade, P., Hudson, M. R., Paananen, T., Ciszek, R., Smith, G., Ali, I., Rundle, B. K., Ndode-Ekane, X. E., Casillas-Espinosa, P. M., Immonen, R., Puhakka, N., Jones, N., Brady, R. D., Perucca, P., Shultz, S. R., Pitkänen, A., O'Brien, T. J. & Staba, R., 1 Jan 2019, (Accepted/In press) In : Epilepsy Research. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis

Casillas-Espinosa, P. M., Andrade, P., Santana-Gomez, C., Paananen, T., Smith, G., Ali, I., Ciszek, R., Ndode-Ekane, X. E., Brady, R. D., Tohka, J., Hudson, M. R., Perucca, P., Braine, E. L., Immonen, R., Puhakka, N., Shultz, S. R., Jones, N. C., Staba, R. J., Pitkänen, A. & O'Brien, T. J., 1 Jan 2019, (Accepted/In press) In : Epilepsy Research. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Identifying mutations in epilepsy genes: Impact on treatment selection

Perucca, P. & Perucca, E., 1 May 2019, In : Epilepsy Research. 152, p. 18-30 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring

Sivathamboo, S., Farrand, S., Chen, Z., White, E. J., Pattichis, A. A., Hollis, C., Carino, J., Roberts, C. J., Minogue, T., Jones, N. C., Yerra, R., French, C., Perucca, P., Kwan, P., Velakoulis, D., O'Brien, T. J. & Goldin, J., 15 Jan 2019, In : Neurology. 92, 3, p. e194-e204 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Epilepsy

Devinsky, O., Vezzani, A., O'Brien, T. J., Jette, N., Scheffer, I. E., De Curtis, M. & Perucca, P., 3 May 2018, In : Nature Reviews Disease Primers. 4, 24 p., 18024.

Research output: Contribution to journalReview ArticleOtherpeer-review

Generalized polyspike train: An EEG biomarker of drug-resistant idiopathic generalized epilepsy

Sun, Y., Seneviratne, U. K., Perucca, P. C., Chen, Z., Tan, M., O'Brien, T. J., D'souza, W. & Kwan, K. L. P., 6 Nov 2018, In : Neurology. 91, 19, p. e1822-e1830 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Genetics of focal epilepsies: What do we know and where are we heading?

Perucca, P., 1 Nov 2018, In : Epilepsy Currents. 18, 6, p. 356-362 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Heart rate variability measurement in epilepsy: How can we move from research to clinical practice?

Myers, K. A., Sivathamboo, S. & Perucca, P., Dec 2018, In : Epilepsia. 59, 12, p. 2169-2178 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Removing high-frequency oscillations: A prospective multicenter study on seizure outcome

Jacobs, J., Wu, J. Y., Perucca, P. C., Zelmann, R., Mader, M., Dubeau, F., Mathern, G. W., Schulze-Bonhage, A. & Gotman, J., 11 Sep 2018, In : Neurology. 91, 11, p. e1040-e1052 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Sleep-disordered breathing in epilepsy: epidemiology, mechanisms, and treatment

Sivathamboo, S., Perucca, P., Velakoulis, D., Jones, N. C., Goldin, J., Kwan, P. & O'Brien, T. J., 1 Apr 2018, In : Sleep. 41, 4, 15 p., UNSP zsy015.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

The management of epilepsy in children and adults

Perucca, P., Scheffer, I. E. & Kiley, M., 19 Mar 2018, In : Medical Journal of Australia. 208, 5, p. 226-233 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

The phenotype of bilateral hippocampal sclerosis and its management in “real life” clinical settings

Sen, A., Dugan, P., Perucca, P., Costello, D., Choi, H., Bazil, C., Radtke, R., Andrade, D., Depondt, C., Heavin, S., Adcock, J., Pickrell, W. O., McGinty, R., Nascimento, F., Smith, P., Rees, M. I., Kwan, P., O'Brien, T. J., Goldstein, D. & Delanty, N., 1 Jul 2018, In : Epilepsia. 59, 7, p. 1410-1420 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Familial mesial temporal lobe epilepsy and the borderland of déjà vu

Perucca, P., Crompton, D. E., Bellows, S. T., McIntosh, A. M., Kalincik, T., Newton, M. R., Vajda, F. J. E., Scheffer, I. E., Kwan, P., O'Brien, T. J., Tan, K. M. & Berkovic, S. F., 1 Aug 2017, In : Annals of Neurology. 82, 2, p. 166-176 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Real-world utility of whole exome sequencing with targeted gene analysis for focal epilepsy

Perucca, P., Scheffer, I. E., Harvey, A. S., James, P. A., Lunke, S., Thorne, N., Gaff, C., Regan, B. M., Damiano, J. A., Hildebrand, M. S., Berkovic, S. F., O'Brien, T. J. & Kwan, P., 1 Mar 2017, In : Epilepsy Research. 131, p. 1-8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Intracranial EEG seizure onset-patterns correlate with high-frequency oscillations in patients with drug-resistant epilepsy

Ferrari-Marinho, T., Perucca, P., Dubeau, F. & Gotman, J., 1 Nov 2016, In : Epilepsy Research. 127, p. 200-206 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity

Oxley, T. J., Opie, N. L., John, S. E., Rind, G. S., Ronayne, S. M., Wheeler, T. L., Judy, J. W., McDonald, A. J., Dornom, A., Lovell, T. J. H., Steward, C., Garrett, D. J., Moffat, B. A., Lui, E. H., Yassi, N., Campbell, B. C. V., Wong, Y. T., Fox, K. E., Nurse, E. S., Bennett, I. E. & 19 othersBauquier, S. H., Liyanage, K. A., Van Der Nagel, N. R., Perucca, P., Ahnood, A., Gill, K. P., Yan, B., Churilov, L., French, C. R., Desmond, P. M., Horne, M. K., Kiers, L., Prawer, S., Davis, S. M., Burkitt, A. N., Mitchell, P. J., Grayden, D. B., May, C. N. & O'Brien, T. J., 1 Mar 2016, In : Nature Biotechnology. 34, 3, p. 320-327 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Prevention and Management of Side‐effects of Antiepileptic Drugs

Zaccara, G. & Perucca, P. C., 2016, The Treatment of Epilepsy. Shorvon, S., Perucca, E. & Engel, Jr., J. (eds.). Fourth ed. UK: Wiley-Blackwell, p. 275-287 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2015

Adverse effects in epilepsy: Recognition, measurement, and taxonomy

Gilliam, F. G., Snavely, L. S. & Perucca, P., 3 Aug 2015, Epilepsy and the Interictal State: Co-morbidities and Quality of Life. St. Louis, E. K., Ficker, D. M. & O’Brien, T. J. (eds.). United State : John Wiley & Sons, p. 102-109 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Epilepsy in 2014: Novel and large collaborations drive advances in epilepsy

Perucca, P. & O'Brien, T. J., 1 Jan 2015, In : Nature Reviews Gastroenterology and Hepatology. 12, 1, p. 60-62 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Epilepsy in 2014: Novel and large collaborations drive advances in epilepsy

Perucca, P. & O'Brien, T. J., 1 Jan 2015, In : Nature Reviews Neurology. 11, 2, p. 74-76 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Gabapentin and pregabalin

Perucca, P. & Dopp, J. M., 16 Jan 2015, Wyllie's Treatment of Epilepsy: Principles and Practice. Wyllie, E. (ed.). 6th ed. Philadelphia : Lippincott Williams & Wilkins, p. 647-657 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Pathologic substrates of focal epilepsy influence the generation of high-frequency oscillations

Ferrari-Marinho, T., Perucca, P., Mok, K., Olivier, A., Hall, J., Dubeau, F. & Gotman, J., 1 Apr 2015, In : Epilepsia. 56, 4, p. 592-598 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Valproate still has a place in women with epilepsy

Perucca, P., O'Brien, T. J., Eadie, M. & Vajda, F. J. E., 1 Jul 2015, In : Epilepsia. 56, 7, p. 1175-1176 2 p.

Research output: Contribution to journalLetterOtherpeer-review

2014

Does gender influence susceptibility and consequences of acquired epilepsies?

Perucca, P., Camfield, P. & Camfield, C., 1 Dec 2014, In : Neurobiology of Disease. 72, PB, p. 125-130 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Intracranial electroencephalographic seizure-onset patterns: Effect of underlying pathology

Perucca, P., Dubeau, F. & Gotman, J., Jan 2014, In : Brain. 137, 1, p. 183-196 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Size of cortical generators of epileptic interictal events and visibility on scalp EEG

von Ellenrieder, N., Beltrachini, L., Perucca, P. & Gotman, J., 1 Jul 2014, In : NeuroImage. 94, p. 47-54 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Antiepileptic drug effects on mood and behavior: Molecular targets

Perucca, P. & Mula, M., Mar 2013, In : Epilepsy and Behavior. 26, 3, p. 440-449 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

High-frequency oscillations, extent of surgical resection, and surgical outcome in drug-resistant focal epilepsy

Haegelen, C., Perucca, P., Châtillon, C. E., Andrade-Valença, L., Zelmann, R., Jacobs, J., Collins, D. L., Dubeau, F., Olivier, A. & Gotman, J., May 2013, In : Epilepsia. 54, 5, p. 848-857 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The adverse event profile of lacosamide: A systematic review and meta-analysis of randomized controlled trials

Zaccara, G., Perucca, P., Loiacono, G., Giovannelli, F. & Verrotti, A., Jan 2013, In : Epilepsia. 54, 1, p. 66-74 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Widespread EEG changes precede focal seizures

Perucca, P., Dubeau, F. & Gotman, J., 19 Nov 2013, In : PLoS ONE. 8, 11, e80972.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2012

Adverse effects of antiepileptic drugs

Perucca, P. & Gilliam, F. G., Sep 2012, In : The Lancet Neurology. 11, 9, p. 792-802 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The adverse effects of antiepileptic drugs differ in patients with migraine - Authors' reply

Gilliam, F. G. & Perucca, P., Nov 2012, In : The Lancet Neurology. 11, 11, p. 935 1 p.

Research output: Contribution to journalLetterOtherpeer-review

The adverse event profile of pregabalin across different disorders: A meta-analysis

Zaccara, G., Perucca, P. & Gangemi, P. F., Jun 2012, In : European Journal of Clinical Pharmacology. 68, 6, p. 903-912 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Adverse antiepileptic drug effects in new-onset seizures: A case-control study

Perucca, P., Jacoby, A., Marson, A. G., Baker, G. A., Lane, S., Benn, E. K. T., Thurman, D. J., Hauser, W. A., Gilliam, F. G. & Hesdorffer, D. C., 18 Jan 2011, In : Neurology. 76, 3, p. 273-279 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Reply from the authors

Perucca, P., Terzaghi, M. & Manni, R., 22 Feb 2011, In : Neurology. 76, 8, p. 761 1 p.

Research output: Contribution to journalLetterOtherpeer-review

Response to first antiepileptic drug trial predicts health outcome in epilepsy

Perucca, P., Hesdorffer, D. C. & Gilliam, F. G., Dec 2011, In : Epilepsia. 52, 12, p. 2209-2215 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The adverse event profile of pregabalin: A systematic review and meta-analysis of randomized controlled trials

Zaccara, G., Gangemi, P., Perucca, P. & Specchio, L., Apr 2011, In : Epilepsia. 52, 4, p. 826-836 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2010

Status epilepticus migrainosus: Clinical, electrophysiologic, and imaging characteristics

Perucca, P., Terzaghi, M. & Manni, R., 27 Jul 2010, In : Neurology. 75, 4, p. 373-374 2 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Adverse antiepileptic drug effects: Toward a clinically and neurobiologically relevant taxonomy

Perucca, P., Carter, J., Vahle, V. & Gilliam, F. G., 7 Apr 2009, In : Neurology. 72, 14, p. 1223-1229 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Broad screening for human herpesviridae DNA in multiple sclerosis cerebrospinal fluid and serum

Franciotta, D., Bestetti, A., Sala, S., Perucca, P., Jarius, S., Price, R. W., Di Stefano, A. L. & Cinque, P., 2009, In : Acta Neurologica Belgica. 109, 4, p. 277-282 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Changes in sex steroid levels in women with epilepsy on treatment: Relationship with antiepileptic therapies and seizure frequency

Galimberti, C. A., Magri, F., Copello, F., Arbasino, C., Chytiris, S., Casu, M., Ameri, P., Perucca, P. & Murialdo, G., Jan 2009, In : Epilepsia. 50, SUPPL. 1, p. 28-32 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Epilepsy treatment as a predeterminant of psychosocial ill health

Perucca, P., Gilliam, F. G. & Schmitz, B., Jun 2009, In : Epilepsy and Behavior. 15, 2 SUPPL. 1

Research output: Contribution to journalArticleResearchpeer-review

Migralepsy: A call for a revision of the definition

Sances, G., Guaschino, E., Perucca, P., Allena, M., Ghiotto, N. & Manni, R., Nov 2009, In : Epilepsia. 50, 11, p. 2487-2496 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Seizure frequency and sex steroids in women with partial epilepsy on antiepileptic therapy

Murialdo, G., Magri, F., Tamagno, G., Ameri, P., Camera, A., Colnaghi, S., Perucca, P., Ravera, G. & Galimberti, C. A., Aug 2009, In : Epilepsia. 50, 8, p. 1920-1926 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Crisi epilettiche e sclerosi multipla: Prevalenza, aspetti clinici e prognostici della comorbilità

Galimberti, C. A., Bergaimaschi, R., Pavan, G. & Perucca, P., May 2008, In : Bollettino - Lega Italiana contro l'Epilessia. 136-137, p. 131-132 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Psychotic disorder and focal epilepsy in a left-handed patient with chromosome XYY abnormality

Verri, A. P., Galimberti, C. A., Perucca, P., Cremante, A., Vernice, M. & Uggetti, A., 2008, In : Genetic Counseling. 19, 4, p. 373-379 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Alterazioni dei livelli sierici di ormoni della sfera riproduttiva, cortisolo e deidroepiandrosterone solfato (DHEAS) in donne con epilessia in trattamento: Ruolo dei farmaci antiepilettici e della frequenza delle crisi

Galimberti, C. A., Magri, F., Copello, F., Arbasino, C., Cravello, L., Casu, M., Patrone, V., Perucca, P. & Murialdo, G., Jul 2006, In : Bollettino - Lega Italiana contro l'Epilessia. 133-134, p. 217-219 3 p.

Research output: Contribution to journalArticleResearchpeer-review