I am a professor in the Department of Biochemistry and Molecular Biology at Monash University. The Department is part of the School of Biomedical Sciences and the Biomedicine Discovery Institute within the Faculty of Medicine, Nursing and Health Sciences.

I am a molecular cell biologist interested in proteases and their regulators operating in the immune and neural systems. I use biochemistry, structural biology, model cell systems and model organisms (mice, zebrafish) in my research.

I received my PhD in E.coli molecular genetics from the University of Melbourne in 1984. I then spent three years in the USA as a Damon Runyon-Walter Winchell Cancer Foundation Fellow working with Professor Joe Sambrook (FRS) on eukaryotic protein trafficking, first at the Cold Spring Harbor Laboratory and then at the University of Texas in Dallas. On my return to Australia I worked at the Commonwealth Serum Laboratories on the cloning and characterizing of pathogen antigens, and then joined the Department of Medicine at Monash University to work on the molecular regulation of blood coagulation. During this time I discovered a new group of human intracellular protease inhibitors (serpins), and my current research interests are focused on the biology of these proteins and their target proteases.