Projects per year
Personal profile
Biography
Peter Wark is a conjoint Professor of Medicine at Monash University, and the Director of Cystic Fibrosis and RES2, AIRMED, Alfred Health, Melbourne. He holds an honorary position as a senior staff specialist in Respiratory and Sleep Medicine at John Hunter Hospital, Newcastle and is an adjunct Professor with the University of Newcastle and senior affiliate researcher at the Hunter Medical Research Institute (HMRI) Immune Health Research programme at HMRI.
He is the Director for the Adult Cystic Fibrosis clinic at the Alfred Hospital that manages the Victorian state-wide Cystic Fibrosis service, providing support to over 340 adult patients with CF in the context of a multidisciplinary team. As director of RES2 he also provides support to people with bronchiectasis and chronic suppurative lung disease. He works in the severe asthma clinic and general respiratory clinics at the Alfred with a special interest in complex airways disease. Since 2009 he has worked within the Commonwealth funded MOICD programme to provide respiratory and sleep outreach support at Narrabri and Moree working with the Kamillori people.
Professor Wark qualified as a Bachelor of Medicine at the University of Newcastle, Australia in 1991. He qualified as a specialist in General and Respiratory and Sleep Medicine and was made a Fellow of the Royal Australasian College of Physicians in 1999. He was awarded a PhD under the supervision of Professors Peter Gibson and Michael Hensley at the University of Newcastle, Australia in 2001.
He was made a Fellow of the Thoracic Society of Australia and New Zealand in 2017. He was awarded a Masters in Clinical trial design from the University of Sydney in 2023.
From 2001-2005, Professor Wark was a post-doctoral research fellow under an NHMRC Neil Hamilton Fairley Travelling Fellowship at the University of Southampton and University College London, under the supervision of Professors Stephen Holgate, Donna Davies and Sebastian Johnston.
He was a member of the TSANZ executive board and chairman of the clinical care and resources subcommittee from 2011 to 2015.
Professor Wark was a senior staff specialist in Respiratory and Sleep Medicine John Hunter Hospital and director of the adult Cystic Fibrosis centre from 2005 to 2023.
He was the medical director for the Respiratory Community of practice with the Agency of Clinical Innovation, NSW health, responsible for supporting respiratory services and practice throughout NSW from February 2020 to June 2023 (during the COVID-19 pandemic) and a member of clinical expert advisory group from August 2022 to June 2023.
Professor Wark is currently on the board of directors for Cystic Fibrosis Australia and the National Asthma Council.
Research interests
Professor Wark's research interests are; airway inflammation in the context of chronic airways disease, innate immunity, the role of infection in chronic airways disease and translational clinical trial design. His group has developed expertise in identifying respiratory viruses in airway secretions and developing an in-vitro cell culture model of the airway epithelium that we use to model the effect of infection and inflammation. His research focuses upon factors that increase susceptibility to virus infection in asthma, COPD, Cystic Fibrosis and bronchiectasis. Characterising airway inflammation and innate immune responses in chronic airways disease and applying this to clinical care, as well as the development of precise individualised management strategies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Newcastle
Award Date: 1 Jun 2001
External positions
Senior Staff Specialist and Consultant Respiratory Physician , Hunter New England Local Health District
Jan 2005 → …
Conjoint Professor and Co-director Priority Research Centre for Healthy Lungs, University of Newcastle
Jan 2005 → …
Research area keywords
- Cystic Fibrosis
- Asthma
- Airway inflammation
- Respiratory virus infection
- Bronchiectasis
Collaborations and top research areas from the last five years
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A Phase 2a, Randomized, Double-Blind, Parallel-Group,Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerabilityof Fexlamose (AER-01) Inhalation Solution in the Treatment of Adults with Moderate to Severe Chronic Obstructive Pulmonary Disease
Wark, P. (Primary Chief Investigator (PCI))
13/03/25 → 13/03/27
Project: Research
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A Randomized, Double-Blind, Multicenter, Active-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Fixed Dose Combination on Severe Asthma Exacerbations in Patients with Asthma
Wark, P. (Primary Chief Investigator (PCI))
17/10/24 → 1/09/27
Project: Research
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Exercise as an adjuvant to vaccination in COPD: feasibility randomised controlled trial
Jones, A. (Primary Chief Investigator (PCI)), Holland, A. (Chief Investigator (CI)), Wark, P. (Chief Investigator (CI)) & van Zelm, M. (Chief Investigator (CI))
3/06/24 → 3/06/25
Project: Research
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A Double-Blind, Active-Controlled, Multiple-Ascending Dose, Phase 1b/2a Study of Aerosolized RSP-1502 Delivered Via the PARI LC Plus® Nebulizer in Subjects with Cystic Fibrosis and Chronic Pseudomonas aeruginosa Lung InfectionA Double-Blind, Active-Controlled, Multiple-Ascending Dose, Phase 1b/2a Study of Aerosolized RSP-1502 Delivered Via the PARI LC Plus® Nebulizer in Subjects with Cystic Fibrosis and Chronic Pseudomonas aeruginosa Lung Infection
Wark, P. (Primary Chief Investigator (PCI)), Allen-Graham, J. (Project Manager) & Smith, D. (Chief Investigator (CI))
16/02/24 → 15/02/26
Project: Research
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Strengthening Healthcare Systems with Patient Reported Outcome Measures (PROMs)
Morton, R. L. (Primary Chief Investigator (PCI)), King, M. (Chief Investigator (CI)), Mercieca-Bebber, R. (Chief Investigator (CI)), Fulcher, G. (Chief Investigator (CI)), Martin, A. J. (Chief Investigator (CI)), Rutherford, C. (Chief Investigator (CI)), Levesque, J.-F. (Chief Investigator (CI)), Sutherland, K. (Chief Investigator (CI)) & Wark, P. (Chief Investigator (CI))
1/09/22 → 31/08/26
Project: Research
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Allergic broncho-pulmonary aspergillosis: Old disease, new frontiers
Denton, E., Wark, P. & Hew, M., Aug 2024, In: Respirology. 29, 8, 3 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
Open Access -
Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients
Thomas, D., McDonald, V. M., Stevens, S., Harvey, E. S., Baraket, M., Bardin, P., Bowden, J. J., Bowler, S., Chien, J., Chung, L. P., Gillman, A., Hew, M., Hodge, S., James, A., Jenkins, C., Katelaris, C. H., Katsoulotos, G. P., Langton, D., Lee, J. & Marks, G. & 9 others, , Feb 2024, In: Allergy. 79, 2, p. 384-392 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access33 Citations (Scopus) -
Cough in Children and Adults: Diagnosis, Assessment and Management (CICADA). Summary of an updated position statement on chronic cough in Australia
Marchant, J. M., Chang, A. B., Kennedy, E., King, D., Perret, J. L., Schultz, A., Toombs, M. R., Versteegh, L., Dharmage, S. C., Dingle, R., Fitzakerley, N., George, J., Holland, A., Rigby, D., Mann, J., Mazzone, S., OBrien, M., O'Grady, K. A., Petsky, H. L. & Pham, J. & 4 others, , Jan 2024, In: The Medical Journal of Australia. 220, 1, p. 35-45 11 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access13 Citations (Scopus) -
BEAT CF pulmonary exacerbations core protocol for evaluating the management of pulmonary exacerbations in people with cystic fibrosis
Schultz, A., McLeod, C., Berry, S., Marsh, J., McKenzie, A., Messer, M., Wood, J., Saville, B., Jaffe, A., Ranganathan, S., Stick, S., Wark, P., Webb, S. & Snelling, T., Dec 2023, In: Trials. 24, 1, 15 p., 211.Research output: Contribution to journal › Article › Other › peer-review
Open Access3 Citations (Scopus) -
Regional variation in prevalence of difficult-to-treat asthma and oral corticosteroid use for patients in Australia: heat map analysis
Wark, P. A. B., Hew, M., Xu, Y., Ghisla, C., Nguyen, T. M., Erdemli, B., Samant, A. & Nan, C., 3 Apr 2023, In: Journal of Asthma. 60, 4, p. 727-736 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)
Prizes
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Fellow of the Thoracic Society of Australia and New Zealand
Wark, P. (Recipient), 2016
Prize: Prize (including medals and awards)
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The Asia Pacific Society of Respirology, Fukuci Award, Best original research paper in Respirology
Wark, P. (Recipient), 2021
Prize: Prize (including medals and awards)
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The Vice Chancellor’s Award for collaboration in research for the Severe Asthma Online Toolkit
Wark, P. (Recipient), 2018
Prize: Prize (including medals and awards)