Projects per year
Personal profile
Biography
Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences
Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences
Research interests
- Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
- The design and synthesis of cancer therapeutics based on Noscapine
- New methodology for the preparation of semi-synthetic opioid pharmaceuticals
- The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
- Applications of ionic liquids in pharmaceutical synthesis and drug delivery
Monash teaching commitment
Bachelor of Pharmaceutical Science:
- PSC2021 Structural Organic Chemistry I (Unit Coordinator)
- PSC3121 Synthetic Medicinal Chemistry (Lecturer)
Education/Academic qualification
PhD, Griffith University
B.Sc. (Hons), Griffith University
External positions
Adjunct Professor, Deakin University
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2001 2024
Multidisciplinary catalyst to discover and progress novel antimalarial drugs
Charman, S., Creek, D., de Koning-Ward, T. F., Gilson, P., McGowan, S. & Scammells, P.
National Health & Medical Research Council (NHMRC)
1/01/20 → 31/12/24
Project: Research
Chemical-Biology Approaches to Pathway Selective Adenosine Receptor Ligands
Scammells, P. & Christopoulos, A.
1/07/19 → 30/06/22
Project: Research
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
New aminobenzimidazole antimalarial agents with a novel mechanism of action
Creek, D., Scammells, P., Ralph, S. A., Norton, R. & Devine, S.
1/01/19 → 31/12/21
Project: Research
Melbourne Biomolecular NMR Network
Stone, M., Bottomley, S., Gooley, P., Langford, S., Reynolds, E., Scammells, P., Scanlon, M., Separovic, F., Tuck, K., Whisstock, J. & Wilce, J.
Australian Research Council (ARC), University of Melbourne, Monash University
1/01/09 → …
Project: Research
Research Output 1986 2019
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells
Yong, C., Devine, S. M., Gao, X., Yan, A., Callaghan, R., Capuano, B. & Scammells, P. J., 1 Jan 2019, (Accepted/In press) In : ChemMedChem.Research output: Contribution to journal › Article › Research › peer-review
2
Citations
(Scopus)
A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor
Fyfe, T. J., Zarzycka, B., Lim, H. D., Kellam, B., Mistry, S. N., Katrich, V., Scammells, P. J., Lane, J. R. & Capuano, B., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 174-206 33 p.Research output: Contribution to journal › Article › Research › peer-review
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
1
Citation
(Scopus)
Effects of VCP979 Novel p38 Mitogen Activated Protein Kinase Inhibitor on Progression of Pancreatic Cancer in Mouse Model with Diabetic Conditions
Xu, T., Ding, J., Ge, H., Xu, X., Scammells, P., Wang, B. & Ju, S., 1 Jun 2019, In : Journal of Biomedical Nanotechnology. 15, 6, p. 1325-1333 9 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2013 2013
- 1 Grant review responsibilities
Theme Leader
Peter Scammells (Member)12 Aug 2013
Activity: External Academic Engagement › Grant review responsibilities