1986 …2020

Research output per year

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Personal profile

Biography

Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences

Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences

Research interests

  • Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
  • The design and synthesis of cancer therapeutics based on Noscapine
  • New methodology for the preparation of semi-synthetic opioid pharmaceuticals
  • The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
  • Applications of ionic liquids in pharmaceutical synthesis and drug delivery

Monash teaching commitment

Bachelor of Pharmaceutical Science:

  • PSC2021 Structural Organic Chemistry I (Unit Coordinator)
  • PSC3121 Synthetic Medicinal Chemistry (Lecturer)

Education/Academic qualification

PhD, Griffith University

Award Date: 2 Apr 1991

B.Sc. (Hons), Griffith University

Award Date: 2 Apr 1986

External positions

Adjunct Professor, Deakin University

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Projects

Research Output

Ionic liquid forms of the antimalarial lumefantrine in combination with LFCS type IIIB lipid-based formulations preferentially increase lipid solubility, in vitro solubilization behavior and in vivo exposure

Tay, E., Nguyen, T. H., Ford, L., Williams, H. D., Benameur, H., Scammells, P. J. & Porter, C. J. H., Jan 2020, In : Pharmaceutics. 12, 1, 25 p., 17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor

Comeo, E., Kindon, N. D., Soave, M., Stoddart, L. A., Kilpatrick, L. E., Scammells, P. J., Hill, S. J. & Kellam, B., 12 Mar 2020, In : Journal of Medicinal Chemistry. 63, 5, p. 2656-2672 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The effect of two selective A1-receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats

Cooper, S. L., March, J., Sabbatini, A. R., Hill, S. J., Jörg, M., Scammells, P. J. & Woolard, J., Jan 2020, In : British Journal of Pharmacology. 177, 2, p. 346-359 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells

Yong, C., Devine, S. M., Gao, X., Yan, A., Callaghan, R., Capuano, B. & Scammells, P. J., 4 Dec 2019, In : ChemMedChem. 14, 23, p. 1968-1981 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Activities

  • 1 Grant review responsibilities

Theme Leader

Peter Scammells (Member)

12 Aug 2013

Activity: External Academic EngagementGrant review responsibilities