Projects per year
Personal profile
Biography
Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences
Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences
Research interests
- Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
- The design and synthesis of cancer therapeutics based on Noscapine
- New methodology for the preparation of semi-synthetic opioid pharmaceuticals
- The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
- Applications of ionic liquids in pharmaceutical synthesis and drug delivery
Monash teaching commitment
Bachelor of Pharmaceutical Science:
- PSC2021 Structural Organic Chemistry I (Unit Coordinator)
- PSC3121 Synthetic Medicinal Chemistry (Lecturer)
Education/Academic qualification
PhD, Griffith University
B.Sc. (Hons), Griffith University
External positions
Adjunct Professor, Deakin University
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2001 2022
New aminobenzimidazole antimalarial agents with a novel mechanism of action
Creek, D., Scammells, P., Ralph, S. A., Norton, R. & Devine, S.
1/01/19 → 31/12/21
Project: Research
Melbourne Biomolecular NMR Network
Stone, M., Bottomley, S., Gooley, P., Langford, S., Reynolds, E., Scammells, P., Scanlon, M., Separovic, F., Tuck, K., Whisstock, J. & Wilce, J.
Australian Research Council (ARC), The University of Melbourne, Monash University
1/01/09 → …
Project: Research
Norbornyl Substituted Adenosine Receptor Ligands: Potential Cardiovascular Pharmaceuticals
Scammells, P. & Baker, S. G.
Australian Research Council (ARC)
1/10/01 → …
Project: Research
Chemical-Biology Approaches to Pathway Selective Adenosine Receptor Ligands
Scammells, P. & Christopoulos, A.
1/07/19 → 30/06/22
Project: Research
Research Output 1986 2019
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases
Vinh, N. B., Drinkwater, N., Malcolm, T. R., Kassiou, M., Lucantoni, L., Grin, P. M., Butler, G. S., Duffy, S., Overall, C. M., Avery, V. M., Scammells, P. J. & McGowan, S., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 622-640 19 p.Research output: Contribution to journal › Article › Research › peer-review
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe
Akter, M., Drinkwater, N., Devine, S. M., Drew, S. C., Krishnarjuna, B., Debono, C. O., Wang, G., Scanlon, M. J., Scammells, P. J., McGowan, S., MacRaild, C. A. & Norton, R. S., 5 Mar 2019, In : ChemMedChem. 14, 5, p. 603-612 10 p.Research output: Contribution to journal › Article › Research › peer-review
Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
Van Der Westhuizen, E. T., Spathis, A., Khajehali, E., Jorg, M., Mistry, S. N., Capuano, B., Tobin, A. B., Sexton, P. M., Scammells, P. J., Valant, C. & Christopoulos, A., 1 May 2018, In : Molecular Pharmacology. 94, 1, p. 770-783 14 p.Research output: Contribution to journal › Article › Research › peer-review
A Structure-Activity Relationship Study of Bitopic N 6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
Aurelio, L., Baltos, J. A., Ford, L., Nguyen, A. T. N., Jörg, M., Devine, S. M., Valant, C., White, P. J., Christopoulos, A., May, L. T. & Scammells, P. J., 8 Mar 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2087-2103 17 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2013 2013
- 1 Grant review responsibilities
Theme Leader
Peter Scammells (Member)12 Aug 2013
Activity: External Academic Engagement › Grant review responsibilities