Projects per year
Personal profile
Biography
Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences
Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences
Research interests
- Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
- The design and synthesis of cancer therapeutics based on Noscapine
- New methodology for the preparation of semi-synthetic opioid pharmaceuticals
- The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
- Applications of ionic liquids in pharmaceutical synthesis and drug delivery
Monash teaching commitment
Bachelor of Pharmaceutical Science:
- PSC2021 Structural Organic Chemistry I (Unit Coordinator)
- PSC3121 Synthetic Medicinal Chemistry (Lecturer)
Education/Academic qualification
PhD, Griffith University
B.Sc. (Hons), Griffith University
External positions
Adjunct Professor, Deakin University
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2001 2022
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
New aminobenzimidazole antimalarial agents with a novel mechanism of action
Creek, D., Scammells, P., Ralph, S. A., Norton, R. & Devine, S.
1/01/19 → 31/12/21
Project: Research
Allosteric and Bitopic Ligands Acting at G Protein-Coupled Receptors
Scammells, P. & Christopoulos, A.
Australian Research Council (ARC), Monash University
1/01/16 → 30/06/19
Project: Research
Melbourne Biomolecular NMR Network
Stone, M., Bottomley, S., Gooley, P., Langford, S., Reynolds, E., Scammells, P., Scanlon, M., Separovic, F., Tuck, K., Whisstock, J. & Wilce, J.
Australian Research Council (ARC), The University of Melbourne, Monash University
1/01/09 → …
Project: Research
Research Output 1986 2019
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor
Fyfe, T. J., Zarzycka, B., Lim, H. D., Kellam, B., Mistry, S. N., Katrich, V., Scammells, P. J., Lane, J. R. & Capuano, B., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 174-206 33 p.Research output: Contribution to journal › Article › Research › peer-review
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases
Vinh, N. B., Drinkwater, N., Malcolm, T. R., Kassiou, M., Lucantoni, L., Grin, P. M., Butler, G. S., Duffy, S., Overall, C. M., Avery, V. M., Scammells, P. J. & McGowan, S., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 622-640 19 p.Research output: Contribution to journal › Article › Research › peer-review
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe
Akter, M., Drinkwater, N., Devine, S. M., Drew, S. C., Krishnarjuna, B., Debono, C. O., Wang, G., Scanlon, M. J., Scammells, P. J., McGowan, S., MacRaild, C. A. & Norton, R. S., 5 Mar 2019, In : ChemMedChem. 14, 5, p. 603-612 10 p.Research output: Contribution to journal › Article › Research › peer-review
Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives
Muthiah, D., Henshaw, G. K., DeBono, A. J., Capuano, B., Scammells, P. J. & Callaghan, R., 1 Feb 2019, In : Drug Metabolism and Disposition. 47, 2, p. 164-172 9 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2013 2013
- 1 Grant review responsibilities
Theme Leader
Peter Scammells (Member)12 Aug 2013
Activity: External Academic Engagement › Grant review responsibilities