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Personal profile


Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences

Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences

Research interests

  • Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
  • The design and synthesis of cancer therapeutics based on Noscapine
  • New methodology for the preparation of semi-synthetic opioid pharmaceuticals
  • The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
  • Applications of ionic liquids in pharmaceutical synthesis and drug delivery

Monash teaching commitment

Bachelor of Pharmaceutical Science:

  • PSC2021 Structural Organic Chemistry I (Unit Coordinator)
  • PSC3121 Synthetic Medicinal Chemistry (Lecturer)

External positions

Adjunct Professor, Deakin University

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Projects 2001 2018

Research Output 2000 2018

A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor

Fyfe, T. J., Zarzycka, B., Lim, H. D., Kellam, B., Mistry, S. N., Katrich, V., Scammells, P. J., Lane, J. R. & Capuano, B. 2018 (Accepted/In press) In : Journal of Medicinal Chemistry. 82 p.

Research output: Contribution to journalArticleResearchpeer-review

The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions

Draper-Joyce, C. J., Verma, R. K., Michino, M., Shonberg, J., Kopinathan, A., Klein Herenbrink, C., Scammells, P. J., Capuano, B., Abramyan, A. M., Thal, D. M., Javitch, J. A., Christopoulos, A., Shi, L. & Lane, J. R. 1 Dec 2018 In : Scientific Reports. 8, 1, 12 p., 1208

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Activities 2013 2013

  • 1 Grant review responsibilities

Theme Leader

Scammells, P. J. (Member)
12 Aug 2013

Activity: Grant review responsibilities