Projects per year
Personal profile
Biography
Medicinal Chemistry Theme Leader, Monash Institute of Pharmaceutical Sciences
Associate Dean, Research, Faculty of Pharmacy & Pharmaceutical Sciences
Research interests
- Allosteric modulators and bitopic ligands acting at G protein-coupled receptors
- The design and synthesis of cancer therapeutics based on Noscapine
- New methodology for the preparation of semi-synthetic opioid pharmaceuticals
- The development of M1 and M17 aminopeptidase inhibitors as antimalarial agents
- Applications of ionic liquids in pharmaceutical synthesis and drug delivery
Monash teaching commitment
Bachelor of Pharmaceutical Science:
-
BPS2021 Synthetic Chemistry I: Structure & Reactivity (Unit Coordinator)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Griffith University
Award Date: 2 Apr 1991
B.Sc. (Hons), Griffith University
Award Date: 2 Apr 1986
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Harnessing Endogenous Opioids to Treat Gut Motility Disorders and Pain
Poole, D., Valant, C., Carbone, S., Mobbs, J., Thal, D., Scammells, P., King, S. K., Imlach, W., Hamilton, J. A. & Veldhuis, N.
1/01/23 → 31/12/26
Project: Research
-
Pre-clinical evaluation of selective adenosine A1 receptor positive allosteric modulators for the treatment of drug-resistant epilepsy
Kwan, P., May, L., Rollo, B., O'Brien, T., Casillas-Espinosa, P., Howden, S., Christopoulos, A., Gregory, K., Scammells, P., Baltos, J., Elliot, D., TN Nguyen, A., Langmead, C., Antonic-Baker, A., Sumer, H., Javaid, S. & Gu, J.
1/06/22 → 31/05/27
Project: Research
-
Positive allosteric modulation of anti-convulsant G protein-coupled receptor signalling to treat drug-resistant epilepsy
May, L., Webb, G., Carlsson, J., Baltos, J., TN Nguyen, A., Christopoulos, A., Miao, Y., O'Brien, T., Rollo, B., Casillas-Espinosa, P., Gregory, K., Scammells, P. & Nguyen, T.
1/01/22 → 31/12/25
Project: Research
-
Multidisciplinary catalyst to discover and progress novel antimalarial drugs
Creek, D., Charman, S., de Koning-Ward, T. F., Gilson, P., McGowan, S. & Scammells, P.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/20 → 31/12/25
Project: Research
-
Newcastle University/Monash Academic Track (NUMAcT) scheme
Mann, D. A., Porter, C. & Scammells, P.
1/08/19 → 31/05/25
Project: Other
-
Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M4 mAChR
Jörg, M., van der Westhuizen, E. T., Lu, Y., Christopher Choy, K. H., Shackleford, D. M., Khajehali, E., Tobin, A. B., Thal, D. M., Capuano, B., Christopoulos, A., Valant, C. & Scammells, P. J., 5 Oct 2023, In: European Journal of Medicinal Chemistry. 258, 20 p., 115588.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1′-region optimisation
Calic, P. P. S., Vinh, N. B., Webb, C. T., Malcolm, T. R., Ngo, A., Lowes, K., Drinkwater, N., McGowan, S. & Scammells, P. J., 15 Feb 2023, In: European Journal of Medicinal Chemistry. 248, 27 p., 115051.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids
Lai, A., Leong, N., Zheng, D., Ford, L., Nguyen, T. H., Williams, H. D., Benameur, H., Scammells, P. J. & Porter, C. J. H., 3 Jun 2022, In: Pharmaceutical Research. 39, p. 2405–2419 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Examining the Role of the Linker in Bitopic N6-Substituted Adenosine Derivatives Acting as Biased Adenosine A1Receptor Agonists
Awalt, J. K., Nguyen, A. T. N., Fyfe, T. J., Thai, B. S., White, P. J., Christopoulos, A., Jörg, M., May, L. T. & Scammells, P. J., 21 Jun 2022, In: Journal of Medicinal Chemistry. 65, 13, p. 9076–9095 20 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway
Edgar, R. C. S., Siddiqui, G., Hjerrild, K., Malcolm, T. R., Vinh, N. B., Webb, C. T., Holmes, C., MacRaild, C. A., Chernih, H. C., Suen, W. W., Counihan, N. A., Creek, D. J., Scammells, P. J., McGowan, S. & de Koning-Ward, T. F., 13 Sept 2022, In: eLife. 11, 32 p., e80813.Research output: Contribution to journal › Article › Research › peer-review
Open Access13 Citations (Scopus)
-
MONASH UNIVERSITY (Organisational unit)
Peter Scammells (Inventor) & Gaik Orbell (Inventor)
3 Aug 2016Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
-
MONASH UNIVERSITY (Organisational unit)
Peter Scammells (Inventor) & Gaik Orbell (Inventor)
14 Apr 2016Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
-
MONASH UNIVERSITY (Organisational unit)
Gaik Orbell (Inventor) & Peter Scammells (Inventor)
7 Jul 2015Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent
-
Theme Leader
Peter Scammells (Member)
12 Aug 2013Activity: External Academic Engagement › Grant review responsibilities