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Personal profile


Prof. Peter Gibson is Head of Luminal Gastroenterology Research, in the Department of Gastroenterology at the Central Clinical School.  

This diverse program targets many chronic and common gastrointestinal conditions:

Clinical Inflammatory Bowel Disease (IBD)

Clinical IBD research projects are investigating several aspects of the disease and its treatment.

Optimising the use of thiopurine immunomodulators

Two studies are focusing on the use of metabolite monitoring to optimize thiopurine immunomodulators - AAA study examining the use of concomitant allopurinol thiopurines in selected patients, and the EATME study in which the rational use of metabolites during the initiation of theipurine therapy is being addressed

The clinical value of anti-TNF drug level monitoring

The use of serum drug and antibody levels in improving outcomes with anti-TNF agents

Multi-centre clinical trials of new therapies

We are an investigating centre for industry-sponsored randomised controlled trials. These include the use of adhesion-molecule blocking antibodies and chemokine-receptor blocking small molecules in patients with refractory Crohn’s disease, and adhesion-molecule blocking antibodies in ulcerative colitis.

Collaborative research projects

Collaborative research projects include the study of mesenchymal stem cells as a therapy for Crohn’s disease patients refractory to biological therapies, and others as part of the Australia and New Zealand IBD Consortium.

Basic mechanisms in IBD

Current projects involve the role of vitamin D and the renin-angiotensin system in the pathogenesis and treatment of IBD.

Functional gastrointestinal disorders

Work includes defining mechanisms underlying the success or otherwise of the Low FODMAP diet, and evaluation of specific nutriceuticals in IBS.

Coeliac disease

Work on new ways of treating patients with coeliac disease and how coeliac disease might influence cognitive function.

Eosinophilic oesophagitis

A new program of studies on the pathogenesis and treatment of this increasingly common condition has been launched.

Research area keywords

  • Digestive disease
  • Gastroenterology
  • Nutrition/Dietetics
  • Inflammatory bowel disease

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2002 2021

Research Output 1992 2019

2 Citations (Scopus)

Controversies and reality of the FODMAP diet for patients with irritable bowel syndrome

Halmos, E. P. & Gibson, P. R., 8 Mar 2019, (Accepted/In press) In : Journal of Gastroenterology and Hepatology (Australia). 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
5 Citations (Scopus)

Gluten-free and low-FODMAP sourdoughs for patients with coeliac disease and irritable bowel syndrome: A clinical perspective

Muir, J. G., Varney, J. E., Ajamian, M. & Gibson, P. R., 2 Feb 2019, In : International Journal of Food Microbiology. 290, p. 237-246 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn’s Disease

Vasudevan, A., Raghunath, A., Anthony, S., Scanlon, C., Sparrow, M. P., Gibson, P. R. & van Langenberg, D. R., 15 Jun 2019, In : Digestive Diseases and Sciences. 64, 6, p. 1622-1631 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: Novel therapeutic target?

Garg, M., Royce, S. G., Tikellis, C., Shallue, C., Batu, D., Velkoska, E., Burrell, L. M., Patel, S. K., Beswick, L., Jackson, A., Britto, K., Lukies, M., Sluka, P., Wardan, H., Hirokawa, Y., Tan, C. W., Faux, M., Burgess, A. W., Hosking, P., Monagle, S. & 3 others, Thomas, M., Gibson, P. R. & Lubel, J., 13 Aug 2019, (Accepted/In press) In : Gut. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Intestinal gases: influence on gut disorders and the role of dietary manipulations

Kalantar-Zadeh, K., Berean, K. J., Burgell, R., Muir, J. & Gibson, P. R., Sep 2019, (Accepted/In press) In : Nature Reviews Gastroenterology & Hepatology. 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review