Projects per year
Personal profile
Biography
Prof. Peter Gibson is Head of Luminal Gastroenterology Research, in the Department of Gastroenterology at the Central Clinical School.
This diverse program targets many chronic and common gastrointestinal conditions:
Clinical Inflammatory Bowel Disease (IBD)
Clinical IBD research projects are investigating several aspects of the disease and its treatment.
Optimising the use of thiopurine immunomodulators
Two studies are focusing on the use of metabolite monitoring to optimize thiopurine immunomodulators - AAA study examining the use of concomitant allopurinol thiopurines in selected patients, and the EATME study in which the rational use of metabolites during the initiation of theipurine therapy is being addressed
The clinical value of anti-TNF drug level monitoring
The use of serum drug and antibody levels in improving outcomes with anti-TNF agents
Multi-centre clinical trials of new therapies
We are an investigating centre for industry-sponsored randomised controlled trials. These include the use of adhesion-molecule blocking antibodies and chemokine-receptor blocking small molecules in patients with refractory Crohn’s disease, and adhesion-molecule blocking antibodies in ulcerative colitis.
Collaborative research projects
Collaborative research projects include the study of mesenchymal stem cells as a therapy for Crohn’s disease patients refractory to biological therapies, and others as part of the Australia and New Zealand IBD Consortium.
Basic mechanisms in IBD
Current projects involve the role of vitamin D and the renin-angiotensin system in the pathogenesis and treatment of IBD.
Functional gastrointestinal disorders
Work includes defining mechanisms underlying the success or otherwise of the Low FODMAP diet, and evaluation of specific nutriceuticals in IBS.
Coeliac disease
Work on new ways of treating patients with coeliac disease and how coeliac disease might influence cognitive function.
Eosinophilic oesophagitis
A new program of studies on the pathogenesis and treatment of this increasingly common condition has been launched.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Digestive disease
- Gastroenterology
- Nutrition/Dietetics
- Inflammatory bowel disease
- FODMAPS
Collaborations and top research areas from the last five years
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FAD-UC: Investigating the therapeutic potential of a diet low in sulphite- & carrageenan food additives for ulcerative colitis
Yao, C., Gibson, P., Biesiekierski, J., Halmos, E., Fitzpatrick, J. W. & Ardalan, Z.
1/09/23 → 30/11/24
Project: Research
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Centre for Research Excellence in Digestive Health
Talley, N., Holtmann, G. J., Walker, M. M., Jones, M., Morrison, M., Keely, S., Gibson, P., Chan, S., Tack, J. & Coombes, J. S.
1/11/19 → 31/10/24
Project: Research
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Asia-Pacific guidelines for managing functional dyspepsia overlapping with other gastrointestinal symptoms
Gwee, K. A., Lee, Y. Y., Suzuki, H., Ghoshal, U. C., Holtmann, G., Bai, T., Barbara, G., Chen, M. H., Chua, A. S. B., Gibson, P. R., Hou, X., Liu, J., Nakajima, A., Pratap, N., Sachdeva, S., Siah, K. T. H., Soh, A. Y. S., Sugano, K., Tack, J., Tan, V. P. Y., & 6 others , Feb 2023, In: Journal of Gastroenterology and Hepatology. 38, 2, p. 197-209 13 p.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access5 Citations (Scopus) -
Lessons from an audit of exclusive enteral nutrition in adult inpatients and outpatients with active Crohn's disease: A single-centre experience
Melton, S. L., Fitzpatrick, J. A., Taylor, K. M., Halmos, E. P. & Gibson, P. R., Jan 2023, In: Frontline Gastroenterology. 14, 1, 8 p.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Letter: dietitians are more than coaches
Gibson, P. R., Apr 2023, In: Alimentary Pharmacology and Therapeutics. 57, 8, p. 926-927 2 p.Research output: Contribution to journal › Letter › Other › peer-review
Open Access -
Pharmacist-Driven Therapeutic Infliximab Monitoring at the Point of Care Using Rapidly Assessed Drug Levels in Patients with Inflammatory Bowel Disease
Rentsch, C. A., Ward, M. G., Luber, R. P., Taylor, K. M., Gibson, D. J., Headon, B., Rosella, O., Su, H. Y., Friedman, A. B., Dooley, M., Sparrow, M. P. & Gibson, P. R., Jun 2023, In: Therapeutic Drug Monitoring. 45, 3, p. 383-391 9 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Review article: Mechanisms underlying the effectiveness of exclusive enteral nutrition in Crohn's disease
Melton, S. L., Taylor, K. M., Gibson, P. R. & Halmos, E. P., May 2023, In: Alimentary Pharmacology and Therapeutics. 57, 9, p. 932-947 16 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus)