Projects per year
Personal profile
Biography
From their birth till their destruction, RNAs are always associated with proteins. Deciphering the language of how RNAs interact with specific RNA-binding proteins is a fundamentally important concept in modern molecular cell biology. Our laboratory has two main focuses. First, we are working on understanding how specific mRNAs are selected for post-transcriptional gene regulation during germ cell development. Second, we are investigating the biogenesis and function of a new family of small RNAs (22G endo-siRNAs) and how they help to maintain the genome integrity by modulation the transcriptional program of germ cells. We use a diverse set of experimental approaches, including cell biology, genetics, biochemistry and genomics to study the RNA pathways of the multicellular eukaryotic model organism C. elegans.
External positions
Adjunct, University of Melbourne
Research area keywords
- Small RNA
- Development
- C. elegans
- Genomics
- RNA Biology
Network
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Harnessing next-generation technologies to tackle major food-borne parasites and design new interventions
Gasser, R., Boag, P., Young, N., Chang, B., Pozio, E. & Sternberg, P.
Australian Research Council (ARC)
Project: Research
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Function and Structure of RIO kinases
Boag, P., Gasser, R. & Hofmann, A.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/13 → 31/12/15
Project: Research
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The 3' UTR codes that control mRNA translation in development
National Health and Medical Research Council (NHMRC) (Australia)
1/01/13 → 31/12/15
Project: Research
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A High-Throughput Phenotypic Screen of the ‘Pandemic Response Box’ Identifies a Quinoline Derivative with Significant Anthelmintic Activity
Shanley, H. T., Taki, A. C., Byrne, J. J., Jabbar, A., Wells, T. N. C., Samby, K., Boag, P. R., Nguyen, N., Sleebs, B. E. & Gasser, R. B., Feb 2022, In: Pharmaceuticals. 15, 2, 15 p., 257.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Natural products are a promising source for anthelmintic drug discovery
Dilrukshi Jayawardene, K. L. T., Palombo, E. A. & Boag, P. R., Oct 2021, In: Biomolecules. 11, 10, 17 p., 1457.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus) -
Practical high-throughput method to screen compounds for anthelmintic activity against caenorhabditis elegans
Taki, A. C., Byrne, J. J., Boag, P. R., Jabbar, A. & Gasser, R. B., Jul 2021, In: Molecules. 26, 14, 7 p., 4156.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Distinct roles of two eIF4E isoforms in the germline of Caenorhabditis elegans
Huggins, H. P., Subash, J. S., Stoffel, H., Henderson, M. A., Hoffman, J. L., Buckner, D. S., Sengupta, M. S., Boag, P. R., Lee, M. H. & Keiper, B. D., 30 Mar 2020, In: Journal of Cell Science. 133, 6, 16 p., jcs237990.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile7 Citations (Scopus) -
WormCat: An online tool for annotation and visualization of caenorhabditis elegans genome-scale data
Holdorf, A. D., Higgins, D. P., Hart, A. C., Boag, P. R., Pazour, G. J., Walhout, A. J. M. & Walker, A. K., 1 Feb 2020, In: Genetics. 214, 2, p. 279-294 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile23 Citations (Scopus)